People Background Check
Find People:

Aaron E Carnes, Age 462733 Jacs Ln, Lincoln, NE 68523

Get Report
Known as:
Aaron E Cames
Related to:
Emmett H Carnes Tracie R Munsch

Aaron Carnes Phones & Addresses

9630 Cotswold Ln, Lincoln, NE 68526 (531) 218-0343

3155 Mayflower Ave, Lincoln, NE 68502

2225 R St, Lincoln, NE 68503 (402) 474-7096

2225 R St #1, Lincoln, NE 68503 (402) 474-7096

Beloit, KS

Beatrice, NE

Work

Position: Professional Specialty Occupations

Mentions for Aaron E Carnes

Aaron Carnes resumes & CV records

Resumes

Aaron Carnes Photo 26

Vice President Of Manufacturing

Location:
4701 Innovation Dr, Lincoln, NE 68521
Industry:
Biotechnology
Work:
Nature Technology Corporation Dec 2001 - Oct 2015
Director of Process Development Nature Technology Corporation Dec 2001 - Oct 2015
Vice President of Manufacturing
Education:
University of Nebraska - Lincoln 1997 - 2001
Skills:
Biotechnology, Purification, Technology Transfer, Biochemistry, Downstream Processing, R&D, Protein Purification, Microbiology, Dna, Fermentation, Process Simulation, Recombinant Dna Technology, Bioprocessing, Virology, Aseptic Processing, Filtration
Certifications:
Vaccine Trials: Methods and Best Practices
Aaron Carnes Photo 27

Aaron Carnes

Publications & IP owners

Us Patents

Process For Plasmid Dna Fermentation

US Patent:
2007025, Nov 1, 2007
Filed:
Aug 16, 2005
Appl. No.:
11/573825
Inventors:
Aaron Carnes - Lincoln NE, US
James Williams - Lincoln NE, US
Assignee:
NATURE TECHNOLOGY CORP. - Lincoln NE
International Classification:
C12P 19/34
C12N 15/64
US Classification:
435091200, 435091100
Abstract:
Improvements in plasmid DNA production technology are needed to insure the economic feasibility of future DNA vaccines and DNA therapeutics. General methods are described, by means of which it is possible to dramatically increase plasmid DNA productivity in a fermentor. These processes feature Fed-batch fermentation strategies, combined with novel growth and induction phase temperature shifts.

Fermentation Process For Continuous Plasmid Dna Production

US Patent:
2008031, Dec 25, 2008
Filed:
Jan 31, 2007
Appl. No.:
12/162689
Inventors:
Aaron E. Carnes - Lincoln NE, US
Assignee:
NATURE TECHNOLOGY CORPORATION - Lincoln NE
International Classification:
C12N 15/64
US Classification:
435 914
Abstract:
A continuous process is described for the production of microbial plasmid DNA for use in biopharmaceutical and biotechnological applications. The process consists of: first growing microbial cells containing a plasmid at a reduced temperature in a continuous stage; followed by a second plasmid induction continuous culture stage with an increased temperature, with a residence time that allows accumulation of the plasmid product. A hold step at a reduced temperature after fermentation further increases the yield of plasmid product. The method enables production of a large quantity of highly purified plasmid DNA from a small bioreactor over time.

E. Coli Plasmid Dna Production

US Patent:
2010018, Jul 22, 2010
Filed:
May 22, 2008
Appl. No.:
12/601504
Inventors:
James A. Williams - Lincoln NE, US
Clague P. Hodgson - Omaha NE, US
Aaron E. Carnes - Lincoln NE, US
Assignee:
NATURE TECHNOLOGY CORPORATION - Lincoln NE
International Classification:
C12N 15/64
C12N 1/21
US Classification:
435 914, 4352523, 43525233
Abstract:
General methods and strains of bacteria are described, that dramatically simplify and streamline plasmid DNA production. In one preferred embodiment, endolysin mediated plasmid extraction combined with flocculation mediated removal of cell debris and host nucleic acids achieves increased yield and purity with simplified downstream purification and reduced waste streams, thus reducing production costs.

Process For Plasmid Dna Fermentation

US Patent:
2011028, Nov 17, 2011
Filed:
May 16, 2011
Appl. No.:
13/108294
Inventors:
Aaron E. CARNES - Lincoln NE, US
James A. Williams - Lincoln NE, US
Assignee:
Nature Technology Corp. - Lincoln NE
International Classification:
C12P 19/34
US Classification:
435 911
Abstract:
Improvements in plasmid DNA production technology are needed to insure the economic feasibility of future DNA vaccines and DNA therapeutics. General methods are described, by means of which it is possible to dramatically increase plasmid DNA productivity in a fermentor. These processes feature fed-batch fermentation strategies, combined with novel growth and induction phase temperature shifts.

E. Coli Plasmid Dna Production

US Patent:
2016035, Dec 8, 2016
Filed:
Feb 3, 2015
Appl. No.:
14/612968
Inventors:
- Lincoln NE, US
CLAGUE P. HODGSON - OMAHA NE, US
AARON E. CARNES - LINCOLN NE, US
International Classification:
C12N 15/64
C12N 15/10
Abstract:
General methods and strains of bacteria are described that dramatically simplify and streamline plasmid DNA production. In one preferred embodiment, endolysin mediated plasmid extraction combined with flocculation mediated removal of cell debris and host nucleic acids achieves increased yield and purity with simplified downstream purification and reduced waste streams, thus reducing production costs.

E. Coli Plasmid Dna Production

US Patent:
2015022, Aug 13, 2015
Filed:
Feb 3, 2015
Appl. No.:
14/612960
Inventors:
- Lincoln NE, US
AARON E. CARNES - LINCOLN NE, US
International Classification:
C12N 15/73
Abstract:
General methods and strains of bacteria are described that dramatically simplify and streamline plasmid DNA production. In one preferred embodiment, endolysin mediated plasmid extraction combined with flocculation mediated removal of cell debris and host nucleic acids achieves increased yield and purity with simplified downstream purification and reduced waste streams, thus reducing production costs.

E. Coli Plasmid Dna Production

US Patent:
2015020, Jul 23, 2015
Filed:
Feb 3, 2015
Appl. No.:
14/612952
Inventors:
- Lincoln NE, US
AARON E. CARNES - LINCOLN NE, US
International Classification:
C12N 15/64
Abstract:
General methods and strains of bacteria are described that dramatically simplify and streamline plasmid DNA production. In one preferred embodiment, endolysin mediated plasmid extraction combined with flocculation mediated removal of cell debris and host nucleic acids achieves increased yield and purity with simplified downstream purification and reduced waste streams, thus reducing production costs.

Possible Relatives

Dale Carnes  Daniel C Carnes  Darren S Carnes  Diana Carnes  Doris M Carnes  Douglas A Carnes  Emily J Carnes  Aaron D Johnson  Aaron M Stang  Aaron M White 

NOTICE: You may not use PeopleBackgroundCheck or the information it provides to make decisions about employment, credit, housing or any other purpose that would require Fair Credit Reporting Act (FCRA) compliance. PeopleBackgroundCheck is not a Consumer Reporting Agency (CRA) as defined by the FCRA and does not provide consumer reports.