Alejandro S ChavezNew York, NY

Alejandro Chavez Phones & Addresses

New York, NY

Windsor, CA

Plantation, FL

Santa Rosa, CA

San Diego, CA

Work

Company: Jcpenney Nov 2009 Position: Sales associate

Education

School / High School: Florida International University- Miami, FL 2011 Specialities: Bachelors of Arts in Psychology

Mentions for Alejandro S Chavez

Career records & work history

Medicine Doctors

Alejandro Chavez Photo 1

Alejandro Chavez

Specialties:
Anatomic Pathology & Clinical Pathology

License Records

Alejandro Chavez

Phone:
(818) 287-1224
Licenses:
License #: 296091 - Expired
Category: Apprentice Electrician
Expiration Date: Nov 13, 2015

Alejandro Chavez resumes & CV records

Resumes

Alejandro Chavez Photo 42

Alejandro Chavez - Pembroke Pines, FL

Work:
JCPenney Nov 2009 to 2000
Sales Associate
Education:
Florida International University - Miami, FL 2011 to 2014
Bachelors of Arts in Psychology
Miami Dade College - Miami, FL 2008 to 2011
Associate of Arts in Psychology
Barbara Goleman Senior High - Miami Lakes, FL 2004 to 2008
High School Diploma

Publications & IP owners

Us Patents

Mutant Cas Proteins

US Patent:
2020029, Sep 17, 2020
Filed:
Mar 16, 2017
Appl. No.:
16/086067
Inventors:
- Cambridge MA, US
Alejandro Chavez - New York NY, US
Assignee:
President and Fellows of Harvard College - Cambridge MA
International Classification:
C12N 9/22
Abstract:
CRISPR/Cas Systems are provided where mutant Cas9 proteins or Cas9 proteins are provided that have improved binding to a target nucleic acid sequence having a functional PAM compared to wild type Cas9 or that bind to a target nucleic acid that lacks a functional PAM.

Methods Of Modulating Expression Of Target Nucleic Acid Sequences In A Cell

US Patent:
2019037, Dec 12, 2019
Filed:
Mar 13, 2018
Appl. No.:
16/486586
Inventors:
- Cambridge MA, US
Alejandro Chavez - New York NY, US
Jing Cheng - Mountain View CA, US
Benjamin W. Pruitt - Cambridge MA, US
Assignee:
President and Fellows of Harvard College - Cambridge MA
International Classification:
C12N 15/11
C12N 9/22
C07K 14/31
C07K 14/315
C12N 15/86
Abstract:
The present disclosure provides methods and compositions of modulating expression of a target nucleic acid sequence in a cell. The method comprises introducing into the cell a nucleic acid sequence encoding a Cas9 fusion protein and a guide RNA, wherein the Cas9 fusion protein and the guide RNA are expressed and co-localize at a target site and modulate the expression of the target nucleic acid sequence.

Mutant Cas9 Proteins

US Patent:
2019036, Dec 5, 2019
Filed:
Jun 13, 2019
Appl. No.:
16/440241
Inventors:
Alejandro Chavez - New York NY, US
Frank J. Poelwijk - Dallas TX, US
George M. Church - Brookline MA, US
Assignee:
President and Fellows of Harvard College - Cambridge MA
International Classification:
C12N 9/22
C07H 21/04
C12Q 1/6897
G01N 33/573
Abstract:
Methods of making mutant Cas9 proteins are described.

Library-Scale Engineering Of Metabolic Pathways

US Patent:
2019026, Aug 29, 2019
Filed:
Jun 12, 2017
Appl. No.:
16/307998
Inventors:
- Cambridge MA, US
Alejandro Chavez - New York NY, US
Max Schubert - Brookline MA, US
Eric Kelsic - Boston MA, US
Assignee:
President and Fellows of Harvard College - Cambridge MA
International Classification:
C12N 15/10
C12N 15/90
Abstract:
Expressing guide nucleic acids (e.g., gRNA) from the same oligonucleotide that contains donor sequence permits the high efficiency, simultaneous transformation of a population of cells with both substrates. Using oligonucleotide chip array technology, one can construct thousands of oligonucleotides with customized gRNA and donor sequence in a cost effective manner. In combination, one can efficiently modify endogenous and exogenous genes.

Methods Of Screening Using Barcoded Libraries

US Patent:
2019016, May 30, 2019
Filed:
Jul 6, 2017
Appl. No.:
16/315230
Inventors:
- Cambridge MA, US
Alejandro Chavez - New York NY, US
International Classification:
C12N 15/10
C12N 9/22
C12N 15/11
Abstract:
A method of screening is provided including providing a combination of a plurality of proliferating cell types wherein each proliferating cell type has a unique associated barcode within its genome that is different from other proliferating cell types of the plurality and wherein each proliferating cell type includes an exogenous gene that when expressed produces an associated phenotype to the proliferating cell type which alters proliferation of the cell type, introducing a perturbation to one or more of the plurality of proliferating cell types, inducing expression of one or more of the exogenous genes, determining the relative number of unique associated barcodes after a period of proliferation, and comparing the relative number of unique associated barcodes to a control relative number of unique associated barcodes to indicate the effect of the perturbation on the one or more of the plurality of proliferating cell types.

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