Amy RosadoOrlando, FL

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Zika Virus Treatment Of Cd24-Positive Tumors And Diseases Associated With Abnormal T Cell Activation And Treating Or Preventing Zika Virus Infections

US Patent:
2019003, Feb 7, 2019
Filed:
Aug 6, 2018
Appl. No.:
16/056086
Inventors:
- Jacksonville FL, US
Terri Helman FINKEL - Orlando FL, US
Joseph MAZAR - Orlando FL, US
Amy Lynn ROSADO - Orlando FL, US
Jiangfang WANG - Orlando FL, US
Tamarah Jeanette WESTMORELAND - Orlando FL, US
Assignee:
THE NEMOURS FOUNDATION - Jacksonville FL
International Classification:
A61K 35/768
C07K 16/28
A61P 35/00
Abstract:
CD24-positive malignant and benign tumors are treated by administration of a naturally occurring or modified oncolytic Zika virus. Diseases associated with abnormal T cell activation or T cell-mediated autoimmunity, wherein CD24 expression is increased, are also expected to be treated by administration of a naturally occurring or modified oncolytic Zika virus. Also contemplated are compounds and methods for treating and/or preventing Zika virus infection in a subject.

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