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Benjamin R Pyles, Age 56Waltham, ME

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Known as:
Benjamin Robert Pyles Ben R Pyles Benjamin Pylas Ben Piles
Related to:
Sean A Pyles

Benjamin Pyles Phones & Addresses

Ellsworth, ME

Columbus, OH

105 2Nd St, Woodland, CA 95695

Davis, CA

39202 Balch Park Rd, Springville, CA 93265 (559) 539-3159

Jericho, VT

Athens, OH

Belle Center, OH

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Mentions for Benjamin R Pyles

Publications & IP owners

Us Patents

Compositions And Methods For Delivering Biotherapeutics

US Patent:
2018034, Dec 6, 2018
Filed:
Aug 23, 2016
Appl. No.:
15/759788
Inventors:
- Oakland CA, US
Benjamin Pyles - Woodland CA, US
Assignee:
Regents of the University of California - Oakland CA
International Classification:
C07K 14/47
A61K 49/00
C07K 14/00
A61P 25/00
Abstract:
Provided herein are compositions and methods relating to cell-penetrating conjugates for the delivery of therapeutic polypeptides or polynucleotides to cells or tissues of the body. The delivery conjugate comprises a cell-penetrating peptide and a nuclear localization signal sequence plus an effector moiety (such as a polypeptide or polynucleotide) as the payload, optionally further including an epitope tag as well as a solubility peptide and a configurating peptide. The delivery conjugate can also include a component capable of specifically directing the conjugate to a target cell or tissue, making the conjugate effective for treating diseases in the target tissue.

Possible Relatives

Deborah S Pyles  Danny L Pyles  Elizabeth A Pyles  Emma J Pyles  Eric B Pyles  Gary G Pyles  George D Pyles  Benjamin B Joiner  Benjamin J Stanton  Benjamin O Staples 

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