Inventors:
Bernard J. Banks - New York NY
Michael J. Witty - New York NY
Assignee:
Pfizer Inc. - New York NY
International Classification:
A61K 3170
C07H 1704
Abstract:
Broad spectrum antiparasitic agents of formula (I) having utility as anthelmintics, ectoparasiticides, insecticides, acaricides and animal growth promotants ##STR1## wherein Y is a single bond or a double bond; R. sup. 1 is OH; provided that when Y is a single bond R. sup. 1 is present and when Y is a double bond R. sup. 1 is absent; R. sup. 2 is. dbd. CH. sub. 2 or a group of the formula --(X)--C(R. sup. 5). dbd. CHR. sup. 6 ; R. sup. 3 is H or CH. sub. 3 ; R. sup. 5 and R. sup. 6 are both H; R. sup. 5 is H and R. sup. 6 is C. sub. 1 -C. sub. 3 alkyl; or one of R. sup. 5 and R. sup. 6 is H and the other is C. sub. 2 -C. sub. 6 alkoxycarbonyl, phenyl, substituted phenyl, heteroaryl or substituted heteroaryl; and X is a direct bond or an alkylene group having from 2 to 6 carbon atoms which may be straight or branched-chain; with the proviso that R. sup. 5 and R. sup. 6 are not both hydrogen when X is --CH(CH. sub. 3)CH. sub. 2 --; processes and intermediates therefor, and compositions thereof.