Beverly A Pawson, Age 90250 Pantops Mountain Rd APT 7302, Charlottesville, VA 22911

Beverly Pawson Phones & Addresses

250 Pantops Mountain Rd APT 7302, Charlottesvle, VA 22911

425 White Gables Ln, Charlottesvle, VA 22903 (434) 978-4647

Charlottesville, VA

144 Red Cedar Ln, Johns Island, SC 29455 (843) 768-7166

Verona, NJ

Montclair, NJ

Mentions for Beverly A Pawson

Publications & IP owners

Us Patents

Polyene Compounds

US Patent:
4061656, Dec 6, 1977
Filed:
Oct 18, 1976
Appl. No.:
5/733507
Inventors:
Michael Josef Klaus - Weil am Rhine, DT
Beverly Ann Pawson - Montclair NJ
Assignee:
Hoffmann-La Roche Inc. - Nutley NJ
International Classification:
C07D33324
A01N 900
US Classification:
2603322A
Abstract:
Novel 9-substituted or unsubstituted thienyl-3,7-dimethyl-nona-2,4,6,8-tetraene derivatives, useful as antitumor agents as well as processes for their preparation and novel intermediates are disclosed.

Fluorinated Polyenes

US Patent:
4335248, Jun 15, 1982
Filed:
Jun 29, 1981
Appl. No.:
6/278224
Inventors:
Ka-Kong Chan - Hopatcong NJ
Beverly A. Pawson - Verona NJ
Assignee:
Hoffmann-La Roche Inc. - Nutley NJ
International Classification:
C07D33316
C07D30712
A61K 3138
A61K 3134
US Classification:
549 78
Abstract:
9-Substituted, 4- or 6-fluorine substituted retinoic acid derivatives useful as antitumor agents and in the treatment of acne as well as a method for their manufacture are disclosed. Substituents at the 9-position include substituted phenyl, thienyl and furyl groups.

Trifluoromethoxy Analogs Of Aromatic Retinoids

US Patent:
4476056, Oct 9, 1984
Filed:
Nov 5, 1982
Appl. No.:
6/439516
Inventors:
Beverly A. Pawson - Verona NJ
Assignee:
Hoffmann-La Roche Inc. - Nutley NJ
International Classification:
C09F 500
C09F 700
C11C 300
C07C 3318
US Classification:
260404
Abstract:
Aromatic retinoids bearing a trifluoromethoxy substituent on the aromatic nucleus which are useful as antitumor agents and in the treatment of dermatological disorders as well as a method for their manufacture are disclosed.

5(Halophenyl)-2-Fluoro-Pentadienals

US Patent:
4395575, Jul 26, 1983
Filed:
Mar 3, 1982
Appl. No.:
6/354331
Inventors:
Ka-Kong Chan - Hopatcong NJ
Beverly A. Pawson - Verona NJ
Assignee:
Hoffmann-La Roche, Inc. - Nutley NJ
International Classification:
C07C 47238
US Classification:
568442
Abstract:
9-Substituted, 4- or 6-fluorine substituted retinoic acid derivatives useful as antitumor agents and in the treatment of acne as well as a method for their manufacture are disclosed. Substituents at the 9-position include substituted phenyl, thienyl and furyl groups.

Polyene Compounds

US Patent:
4230872, Oct 28, 1980
Filed:
May 11, 1978
Appl. No.:
5/904950
Inventors:
Michael J. Klaus - Weil am Rhein, DE
Beverly A. Pawson - Montclair NJ
Assignee:
Hoffmann-La Roche Inc. - Nutley NJ
International Classification:
C07D33324
C07D33326
C07D33328
C07D33330
US Classification:
549 62
Abstract:
Novel 9-substituted or unsubstituted thienyl-3,7-dimethyl-nona-2,4,6,8-tetraene derivatives, useful as antitumor agents as well as processes for their preparation and novel intermediates are disclosed.

Fluorinated Aromatic Polyenes

US Patent:
4375563, Mar 1, 1983
Filed:
Mar 30, 1982
Appl. No.:
6/363706
Inventors:
Ka-Kong Chan - Hopatcong NJ
Beverly A. Pawson - Montclair NJ
Assignee:
Hoffmann-La Roche Inc. - Nutley NJ
International Classification:
C07C 49248
C07C 47263
C07C 4323
US Classification:
568308
Abstract:
Compounds represented by the formula ##STR1## wherein R. sub. 1, R. sub. 2 and R. sub. 3 are lower alkyl, R. sub. 4 is lower alkoxy, R. sub. 6 and R. sub. 8 are methyl or trifluoro methyl, R. sub. 9 is formyl, hydroxymethyl, alkoxymethyl, alkanoyloxymethyl, carboxyl, alkoxycarbonyl, lower alkenoxycarbonyl, lower alkynoxycarbonyl, carbamoyl, mono(lower alkyl)-carbamoyl, di(lower alkyl)carbamoyl or N-heterocyclylcarbonyl, R. sub. 5, R. sub. 7, R. sub. 10, R. sub. 11, R. sub. 12 and R. sub. 13 are hydrogen or fluorine with the proviso that at least one of R. sub. 5, R. sub. 7, R. sub. 10, R. sub. 11, R. sub. 12 or R. sub. 13 is fluorine or at least one of R. sub. 6 or R. sub. 8 is trifluoro methyl, or pharmaceutically acceptable salts thereof useful as antitumor agents are disclosed.

Fluorinated Polyenes

US Patent:
4231944, Nov 4, 1980
Filed:
May 10, 1979
Appl. No.:
6/037803
Inventors:
Ka-Kong Chan - Hopatcong NJ
Beverly A. Pawson - Verona NJ
Assignee:
Hoffmann-La Roche Inc. - Nutley NJ
International Classification:
C07D30716
C07D30712
C07D33324
US Classification:
2603474
Abstract:
9-substituted, 4- or 6-fluorine substituted retinoic acid derivatives useful as antitumor agents and in the treatment of acne as well as a method for their manufacture are disclosed. Substituents at the 9-position include substituted phenyl, thienyl and furyl groups.

Fluorinated Polyenes

US Patent:
4299995, Nov 10, 1981
Filed:
May 13, 1980
Appl. No.:
6/149389
Inventors:
Ka-Kong Chan - Hopatcong NJ
Beverly A. Pawson - Verona NJ
Assignee:
Hoffmann-La Roche Inc. - Nutley NJ
International Classification:
C07C 4302
C07C 3346
A61K 3109
A61K 3105
US Classification:
568649
Abstract:
9-substituted, 4- or 6-fluorine substituted retinoic acid derivatives useful as antitumor agents and in the treatment of acne as well as a method for their manufacture are disclosed. Substituents at the 9-position include substituted phenyl, thienyl and furyl groups.

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