Brian W Craine, Age 431 Lessing Rd, Town Center, NJ 07052

6427022, Jul 30, 2002

Nov 10, 1998

09/189482

Eric R. Craine - Tuscon AZ
Brian L. Craine - Fairfax CA

Western Research Company, Inc. - Tucson AZ

G06K 900

382128, 128922

New or growing skin lesions are identified by providing digital baseline image data of an area of a subjects skin, and storing the baseline image data. An imaging system is operated to produce up-to-date digital image data of the skin area directly from the subject or from a photograph thereof as a real time input to a computer. The stored baseline image data also is provided to the computer. The up-to-date image data and baseline image data are alternately displayed on a monitor in a blinking mode. The orientation, focus, and/or distance of the camera from the actual area or photograph thereof so as to frame, scale, and/or align features of the alternately displayed images. A frame of the aligned up-to-date image is digitized and stored. The stored up-to-date image data and the baseline image data are alternately displayed on a monitor in a blinking mode to visually identify lesions which blink enough to identify a new or significantly growing lesion.

7162063, Jan 9, 2007

Jul 26, 2004

10/899499

Eric R. Craine - Tucson AZ, US
Brian L. Craine - Fairfax CA, US

Western Research Company, Inc. - Tucson AZ

G06K 9/00

382128, 128922

New or significantly changed skin lesions are detected by providing digital baseline image data of an area of a subject's skin by placing a calibration piece on the area and then positioning a digital camera to frame the area within a field of view of the camera and digitally photographing the area to produce a digital baseline image of the area. The digital baseline image is downloaded from the camera to a computer, which digitally filters the baseline image to produce a partially transparent baseline image scaled to fit over a viewfinder display of the camera. The filtered baseline image is printed on a transparent sheet to produce template. Substantially later, a calibration piece is placed on the area, and the template is placed over the viewfinder display of the camera. The camera is positioned to frame that area within the field of view so as to align a live image of the area with the baseline image on the template. The area is photographed to produce a digital current image thereof.

5791346, Aug 11, 1998

Aug 22, 1996

8/670321

Eric R. Craine - Tucson AZ
Brian L. Craine - Fairfax CA

Western Research Company, Inc. - Tucson AZ

A61B 500

1286531

The area of a three-dimensional lesion on a cervix is determined from a two-dimensional image thereof produced by a digital colposcope. A stored reference cervix reflectance map including slant angles and corresponding gray scale intensity levels represents a reference cervix, and is obtained using a shape-assuming target including thereon an array of circular spots of a first reflectivity and a stiff target having thereon a first circular spot of the first reflectivity and a second circular spot of a second reflectivity. An identical stiff target is placed on the cervix, and a two-dimensional image of the lesion and the stiff target is obtained from the digital colposcope. Resulting intensities of the two-dimensional image are calibrated to the gray scale of a standard target reflectance map, and the calibrated intensities of the two-dimensional image are correlated to the intensities of the reference cervix reflectance map to determine slant angles of predetermined points of the cervix. Pixel dimensions of each pixel in the lesion then are corrected in accordance with the slant angles. The lesion area is computed by summing the areas of the pixels with corrected dimensions.