Craig Allan Leach, Age 50100 Lee Cir, Bryn Mawr, PA 19010

Craig Leach Phones & Addresses

100 Lee Cir, Bryn Mawr, PA 19010 (484) 941-4695

222 Chestnut Ave, Ardmore, PA 19003 (610) 658-1915

44 Davis St, Belmont, MA 02478 (617) 484-3130 (617) 932-1849

Norristown, PA

Fairfax, VA

Havertown, PA

Arlington, MA

Charlottesville, VA

Cambridge, MA

Havertown, PA

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Mentions for Craig Allan Leach

Craig Leach resumes & CV records

Resumes

Craig Leach Photo 46

Craig Leach

Skills:
Microsoft Office, Management
Craig Leach Photo 47

Craig Leach

Craig Leach Photo 48

Craig Leach

Publications & IP owners

Us Patents

Di- And Poly-Ubiquitin Deubiquitinase Substrates And Uses Thereof

US Patent:
2012010, May 3, 2012
Filed:
Jun 24, 2011
Appl. No.:
13/168073
Inventors:
Dattananda Chelur - Chesterbrook PA, US
Michael Eddins - West Chester PA, US
Craig Leach - Ardmore PA, US
Steven J. Orcutt - Audubon PA, US
Raymond J. Peroutka - Baltimore MD, US
James Strickler - Havertown PA, US
Yilin Yan - , US
Kathryn Longenecker - West Chester PA, US
International Classification:
C12Q 1/37
C07K 1/107
C12P 21/02
C07K 14/47
US Classification:
435 23, 530409, 435 681, 530408
Abstract:
Methods for detection of the activity of proteolytic enzymes, particularly isopeptidases, are disclosed.

Anti-Neoplastic Compounds, Compositions And Methods

US Patent:
2012011, May 10, 2012
Filed:
Mar 31, 2010
Appl. No.:
13/262422
Inventors:
Ping Cao - Savoy IL, US
Joseph Weinstock - Wayne PA, US
William D. Kingsbury - Wilmington NC, US
Craig A. Leach - Ardmore PA, US
Benjamin Nicholson - Merion Station PA, US
International Classification:
A61K 33/24
A61K 31/381
C07D 417/12
A61K 31/427
C07D 409/12
A61K 31/4178
A61K 31/4436
A61K 31/498
C07D 413/14
A61K 31/5377
C07D 409/14
A61K 31/496
A61K 31/4545
A61K 31/538
A61K 31/704
A61K 38/14
A61K 31/7048
A61K 31/675
A61K 31/475
A61K 31/4745
A61K 31/415
A61P 35/00
A61P 35/02
A61N 5/10
C07D 333/42
US Classification:
424649, 549 63, 514445, 548186, 514369, 5483151, 514397, 5462814, 514336, 544354, 514249, 549 60, 514444, 544131, 5142355, 544364, 51425311, 546193, 514318, 544105, 5142305, 514 34, 514 193, 514 27, 514110, 514283, 514407, 5142358, 600 1
Abstract:
Disclosed are novel compounds which are useful as therapeutics, especially in anti-neoplastic therapy and in other therapeutic regimes where cysteine protease inhibition is implicated.

Di- And Poly-Ubiquitin Deubiquitinase Substrates And Uses Thereof

US Patent:
2014007, Mar 13, 2014
Filed:
Aug 26, 2013
Appl. No.:
13/975941
Inventors:
Craig Leach - Ardmore PA, US
Steven J. Orcutt - Audubon PA, US
Raymond J. Peroutka - Baltimore MD, US
James Strickler - Havertown PA, US
Yilin Yan - Troy NY, US
Kathryn Longenecker - West Chester PA, US
Assignee:
Progenra, Inc. - Malvern PA
Lifesensors, Inc. - Malvern PA
International Classification:
C12Q 1/37
US Classification:
435 24, 530350, 530402, 435 681, 530408
Abstract:
Methods for detection of the activity of proteolytic enzymes, particularly isopeptidases, are disclosed.

Non Peptidic Heterobivalent Molecules For Treating Inflammatory Diseases

US Patent:
2021037, Dec 9, 2021
Filed:
Aug 25, 2021
Appl. No.:
17/412070
Inventors:
- Brentford, GB
Yao CHEN - Collegeville PA, US
Mark HURLE - Collegeville PA, US
Craig LEACH - Collegeville PA, US
Brandon TURUNEN - Collegeville PA, US
International Classification:
A61K 31/454
A61K 31/4375
A61K 31/438
A61K 31/496
A61K 31/499
A61K 31/506
A61K 31/5375
A61K 31/5377
Abstract:
The present invention relates to non peptidic, heterobivalent molecules (HBM) that are able to simultaneously bind a surface target protein as well as an endogenous or exogenous human antibody protein and induce immune effector function. More specifically, the present invention relates to agents capable of binding to a chemokine receptor and inducing the depletion of chemokine receptor positive subsets of pathogenic cells in a subject for use in the treatment and/or prevention of cancer, inflammatory, autoimmune and allergic disease.

Non Peptide Heterobivalent Molecules For Treating Inflammatory Diseases

US Patent:
2019033, Nov 7, 2019
Filed:
Jan 16, 2018
Appl. No.:
16/478551
Inventors:
- Brentford, GB
Yao CHEN - Collegeville PA, US
Mark HURLE - Collegeville PA, US
Craig LEACH - Collegeville PA, US
Brandon TURUNEN - Collegeville PA, US
International Classification:
A61K 31/454
A61K 31/4375
A61K 31/438
A61K 31/496
A61K 31/506
A61K 31/5375
A61K 31/5377
A61K 31/499
Abstract:
The present invention relates to non peptidic, heterobivalent molecules (HBM) that are able to simultaneously bind a surface target protein as well as an endogenous or exogenous human antibody protein and induce immune effector function. More specifically, the present invention relates to agents capable of binding to a chemokine receptor and inducing the depletion of chemokine receptor positive subsets of pathogenic cells in a subject for use in the treatment and/or prevention of cancer, inflammatory, autoimmune and allergic disease.

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