Daniel CafaroOrange, CA

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Orange, CA

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Us Patents

Composition For Preventing The Accumulation Of Inorganic Deposits On Contact Lenses

US Patent:
5447650, Sep 5, 1995
Filed:
Oct 6, 1993
Appl. No.:
8/132606
Inventors:
Daniel P. Cafaro - Santa Ana CA
Assignee:
Allergan, Inc. - Irvine CA
International Classification:
C11D 306
C11D 716
US Classification:
252135
Abstract:
A composition including a neutralizing system and a sequestering agent is described which prevents the accumulation of inorganic deposits on contact lenses, particularly when used regularly in a conventional hydrogen peroxide disinfection regimen. The neutralizing system includes at least one reducing agent, a reductase, or both. The sequestering agent preferably is gluconic acid, a polymetaphosphate or their salts. Sodium hexametaphosphate is the most preferred sequestering agent; catalase is the most preferred agent for use as the neutralizing system.

Compositions And Methods For Disinfecting Contact Lenses And Preserving Contact Lens Care Products

US Patent:
6024954, Feb 15, 2000
Filed:
Aug 2, 1996
Appl. No.:
8/692867
Inventors:
John Y. Park - Santa Ana CA
Lin Peng - Tustin CA
Daniel P. Cafaro - Santa Ana CA
Anthony J. Dziabo - Lake Forest CA
Assignee:
Allergan - Waco TX
International Classification:
A61K 3854
US Classification:
424 942
Abstract:
Compositions for disinfecting contact lenses include a liquid medium containing a chlorite component, preferably a water soluble chlorite component, in a contact lens disinfecting amount, and a polyanionic component, preferably a water soluble polyanionic component, in an amount effective to do at least one of the following: inhibit formation of protein deposit material on a contact lens immersed in the composition; reduce the toxicity of the composition to the human eye, and reduce the damage to a contact lens caused by immersing the contact lens in the composition. The composition has a viscosity of less than 50 cps at 25. degree. C. , an osmolality of at least about 200 mOsmol/kg, and preferably a pH in the range of about 6 to about 9.

Method For Preventing The Accumulation Of Inorganic Deposits On Contact Lenses

US Patent:
5589387, Dec 31, 1996
Filed:
Jun 6, 1995
Appl. No.:
8/470910
Inventors:
Daniel P. Cafaro - Santa Ana CA
Assignee:
Allergan, Inc. - Irvine CA
International Classification:
C11D 306
C11D 716
US Classification:
435264
Abstract:
A method for using a composition including a neutralizing system and a sequestering agent which prevents the accumulation of inorganic deposits on contact lenses, particularly when used regularly in a conventional hydrogen peroxide disinfection regimen. The neutralizing system includes at least one reducing agent, a reductase, or both. The sequestering agent preferably is gluconic acid, a polymetaphosphate or their salts. Sodium hexametaphosphate is the most preferred sequestering agent; catalase is the most preferred agent for use as the neutralizing system.

Compositions And Methods For Storing Contact Lenses

US Patent:
5882687, Mar 16, 1999
Filed:
Jan 10, 1997
Appl. No.:
8/781869
Inventors:
John Y. Park - Tustin CA
Daniel Cafaro - Walnut Creek CA
Anthony J. Dziabo - Lake Forest CA
Assignee:
Allergan - Waco TX
International Classification:
A61K 3016
US Classification:
424682
Abstract:
Compositions for storing contact lenses include a liquid medium containing a polyanionic component, preferably a water soluble polyanionic component, in an amount effective to provide a hydration layer on the surface of said contact lens. The composition has a viscosity of less than 50 cps at 25. degree. C. , an osmolality of at least about 200 mOsm/kg, and preferably a pH in the range of about 6 to about 9.

Compositions And Methods For Disinfecting And Cleaning Contact Lenses

US Patent:
5746972, May 5, 1998
Filed:
Nov 1, 1996
Appl. No.:
8/742356
Inventors:
John Y. Park - Santa Ana CA
Larry K. Thomas - Irvine CA
Lin Peng - Sunnyvale CA
Daniel P. Cafaro - Walnut Creek CA
Assignee:
Allergan - Waco TX
International Classification:
A61L 218
C12N 908
US Classification:
422 30
Abstract:
Compositions and methods for disinfecting and cleaning contact lenses include a liquid medium containing hydrogen peroxide and a defined ethylene oxide/propylene oxide block copolymer. An advantageously reduced amount of foaming occurs when the hydrogen peroxide is destroyed, particularly by the action of catalase.

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