Daniel Ellen L Mufson, Age 82Fairfield, CA
Daniel Mufson Phones & Addresses
Napa, CA
1301 Grosventres Ct, Fremont, CA 94539
Thiells, NY
Menlo Park, CA
Mentions for Daniel Ellen L Mufson
Publications & IP owners
Us Patents
Method Of Forming An Aerosol For Inhalation Delivery
US Patent:
7537009, May 26, 2009
Filed:
May 13, 2002
Appl. No.:
10/146088
Inventors:
Ron L. Hale - Woodside CA, US
Craig C. Hodges - Walnut Creek CA, US
Peter M. Lloyd - Walnut Creek CA, US
Daniel Mufson - Napa CA, US
Daniel D. Rogers - Oakland CA, US
Soonho Song - Stanford CA, US
Martin J. Wensley - San Francisco CA, US
Daniel J. Myers - Mountain View CA, US
Jeffrey A. McKinney - Foster City CA, US
Reynaldo J. Quintana - Redwood City CA, US
Joshua D. Rabinowitz - Mountain View CA, US
Craig C. Hodges - Walnut Creek CA, US
Peter M. Lloyd - Walnut Creek CA, US
Daniel Mufson - Napa CA, US
Daniel D. Rogers - Oakland CA, US
Soonho Song - Stanford CA, US
Martin J. Wensley - San Francisco CA, US
Daniel J. Myers - Mountain View CA, US
Jeffrey A. McKinney - Foster City CA, US
Reynaldo J. Quintana - Redwood City CA, US
Joshua D. Rabinowitz - Mountain View CA, US
Assignee:
Alexza Pharmaceuticals, Inc. - Mountain View CA
International Classification:
A61L 9/04
US Classification:
12820316, 12820014, 424 46
Abstract:
The present invention relates to the inhalation delivery of aerosols containing small particles. Specifically, it relates to a method of forming an aerosol for use in inhalation therapy. In a method aspect of the present invention, a method of forming an aerosol for use in inhalation therapy is provided. The method involves the following steps: (a) heating a substrate coated with a composition comprising a drug at a rate greater than 1000 C. /s, thereby forming an vapor; and, (b) allowing the vapor to cool, thereby forming an aerosol, which is used in inhalation therapy. In another method aspect of the present invention, a method of forming an aerosol for use in inhalation therapy is provided. The method involves the following steps: (a) heating a substrate coated with a composition comprising a drug to form a vapor, wherein the coated composition is in the form of a film less than 10 μ thick; and, (b) allowing the vapor to cool, thereby forming an aerosol, which is used in inhalation therapy. In another method aspect of the present invention, a method of forming an aerosol for use in inhalation therapy is provided.
Aerosol Generating Method And Device
US Patent:
7766013, Aug 3, 2010
Filed:
Oct 26, 2001
Appl. No.:
10/057197
Inventors:
Martin J. Wensley - San Francisco CA, US
Daniel Mufson - Napa CA, US
Craig C. Hodges - Walnut Creek CA, US
Peter M. Lloyd - Walnut Creek CA, US
Daniel D. Rogers - Oakland CA, US
Daniel Mufson - Napa CA, US
Craig C. Hodges - Walnut Creek CA, US
Peter M. Lloyd - Walnut Creek CA, US
Daniel D. Rogers - Oakland CA, US
Assignee:
Alexza Pharmaceuticals, Inc. - Mountain View CA
International Classification:
H05B 3/00
US Classification:
12820327, 12820014, 12820326, 424 45, 424 46
Abstract:
A method and device are provided to generate an aerosol having a desired particle sizes, i. e. , from molecular to about 10 microns, which can be used to effectively deliver a physiologically active compound to organs and tissues such as the lung, eye, mucosa and skin. The aerosol is formed through vaporization of the compound while mixing the resulting vapor with a gas, in a ratio, to form the desired particle size when a stable concentration of particles in the gas is reached.
Aerosol Forming Device For Use In Inhalation Therapy
US Patent:
7942147, May 17, 2011
Filed:
May 13, 2002
Appl. No.:
10/146080
Inventors:
Craig C. Hodges - Walnut Creek CA, US
Peter M. Lloyd - Walnut Creek CA, US
Daniel Mufson - Napa CA, US
Daniel D. Rogers - Oakland CA, US
Martin J. Wensley - San Francisco CA, US
Peter M. Lloyd - Walnut Creek CA, US
Daniel Mufson - Napa CA, US
Daniel D. Rogers - Oakland CA, US
Martin J. Wensley - San Francisco CA, US
Assignee:
Alexza Pharmaceuticals, Inc. - Mountain View CA
International Classification:
H05B 3/00
US Classification:
12820327, 12820014, 12820326
Abstract:
The present invention relates to the inhalation delivery of aerosols containing small particles. Specifically, it relates to a device that forms drug containing aerosols for use in inhalation therapy. In a device aspect of the present invention, a device for delivering drug containing aerosols for inhalation therapy is provided. The device includes a housing and an airway that has a gas/vapor mixing airway. The airway further includes a subassembly, which has a metallic substrate coated on its surface with a composition comprising a drug.
Method Of Forming An Aerosol For Inhalation Delivery
US Patent:
8074644, Dec 13, 2011
Filed:
May 22, 2009
Appl. No.:
12/471070
Inventors:
Ron L. Hale - Sandia Park NM, US
Craig C. Hodges - Walnut Creek CA, US
Peter M. Lloyd - Walnut Creek CA, US
Daniel Mufson - Napa CA, US
Daniel D. Rogers - Oakland CA, US
Soonho Song - Hillsborough CA, US
Martin J. Wensley - Los Gatos CA, US
Daniel J. Myers - Mountain View CA, US
Jeffrey A. McKinney - Lafayette CA, US
Reynaldo J. Quintana - Redwood City CA, US
Joshua D. Rabinowitz - Princeton NJ, US
Craig C. Hodges - Walnut Creek CA, US
Peter M. Lloyd - Walnut Creek CA, US
Daniel Mufson - Napa CA, US
Daniel D. Rogers - Oakland CA, US
Soonho Song - Hillsborough CA, US
Martin J. Wensley - Los Gatos CA, US
Daniel J. Myers - Mountain View CA, US
Jeffrey A. McKinney - Lafayette CA, US
Reynaldo J. Quintana - Redwood City CA, US
Joshua D. Rabinowitz - Princeton NJ, US
Assignee:
Alexza Pharmaceuticals, Inc. - Mountain View CA
International Classification:
A61L 9/04
US Classification:
12820316, 12820014, 424 46
Abstract:
The present invention relates to the inhalation delivery of aerosols containing small particles. Specifically, it relates to a method of forming an aerosol for use in inhalation therapy. In a method aspect of the present invention, a method of forming an aerosol for use in inhalation therapy is provided. The method involves the following steps: (a) heating a substrate coated with a composition comprising a drug at a rate greater than 1000 C. /s, thereby forming an vapor; and, (b) allowing the vapor to cool, thereby forming an aerosol, which is used in inhalation therapy. In another method aspect of the present invention, a method of forming an aerosol for use in inhalation therapy is provided. The method involves the following steps: (a) heating a substrate coated with a composition comprising a drug to form a vapor, wherein the coated composition is in the form of a film less than 10μ thick; and, (b) allowing the vapor to cool, thereby forming an aerosol, which is used in inhalation therapy. In another method aspect of the present invention, a method of forming an aerosol for use in inhalation therapy is provided.
Delivery Of Aerosols Containing Small Particles Through An Inhalation Route
US Patent:
2003003, Feb 20, 2003
Filed:
May 13, 2002
Appl. No.:
10/146515
Inventors:
Craig Hodges - Walnut Creek CA, US
Peter Lloyd - Walnut Creek CA, US
Daniel Mufson - Napa CA, US
Daniel Rogers - Oakland CA, US
Martin Wensley - San Francisco CA, US
Peter Lloyd - Walnut Creek CA, US
Daniel Mufson - Napa CA, US
Daniel Rogers - Oakland CA, US
Martin Wensley - San Francisco CA, US
International Classification:
A61L009/04
A61K009/14
A61K009/14
US Classification:
424/046000
Abstract:
The present invention relates to the inhalation delivery of aerosols containing small particles. Specifically, it relates to the delivery of drug containing aerosols having particles with a mass median aerodynamic diameter less than 1 for inhalation therapy. In a composition aspect of the present invention the drug containing aerosol comprises particles having a mass median aerodynamic diameter between 10 nm and 1. Preferably, the particles have a mass median aerodynamic diameter between 10 nm and 900 nm. More preferably, the particles have a mass median aerodynamic diameter between 10 nm and 800 nm, 10 nm and 700 nm, 10 nm and 600 nm, 10 nm and 500 nm, 10 nm and 400 nm, 10 nm and 300 nm, 10 nm and 200 nm, or 10 nm and 100 nm.
Method And Device For Delivering A Physiologically Active Compound
US Patent:
2003005, Mar 20, 2003
Filed:
Oct 26, 2001
Appl. No.:
10/057198
Inventors:
Peter Lloyd - Walnut Creek CA, US
Martin Wensley - San Francisco CA, US
Daniel Mufson - Napa CA, US
Craig Hodges - Walnut Creek CA, US
Daniel Rogers - Oakland CA, US
Martin Wensley - San Francisco CA, US
Daniel Mufson - Napa CA, US
Craig Hodges - Walnut Creek CA, US
Daniel Rogers - Oakland CA, US
International Classification:
A61M011/00
F23D011/00
A62B007/00
F23D011/00
A62B007/00
US Classification:
128/203260, 128/200140, 128/204130, 128/204250
Abstract:
A method and device are provided to generate an aerosol having a desired particle sizes, i.e., from molecular to about 10 microns, which can be used to effectively deliver a physiologically active compound to organs and tissues such as the lung, eye, mucosa and skin. The aerosol is formed through vaporization of the compound while simultaneously mixing the resulting vapor with air or other gas. The purity of the compound is maintained meet FDA requirements by closely controlling its degradant levels during vaporization.
Delivery Of Aerosols Containing Small Particles Through An Inhalation Route
US Patent:
2004009, May 20, 2004
Filed:
Oct 30, 2003
Appl. No.:
10/696959
Inventors:
Craig Hodges - Walnut Creek CA, US
Peter Lloyd - Walnut Creek CA, US
Daniel Mufson - Napa CA, US
Daniel Rogers - Oakland CA, US
Martin Wensley - San Francisco CA, US
Peter Lloyd - Walnut Creek CA, US
Daniel Mufson - Napa CA, US
Daniel Rogers - Oakland CA, US
Martin Wensley - San Francisco CA, US
Assignee:
Alexza Molecular Delivery Corporation - Palo Alto CA
International Classification:
B29B009/00
A61L009/04
A61K009/14
A61L009/04
A61K009/14
US Classification:
424/046000, 264/005000
Abstract:
The present invention relates to the inhalation delivery of aerosols containing small particles. Specifically, it relates to the delivery of drug containing aerosols having particles with a mass median aerodynamic diameter less than 1 for inhalation therapy. In an aspect of the present invention the drug containing aerosol comprises particles having a mass median aerodynamic diameter between 10 nm and 1. Preferably, the particles have a mass median aerodynamic diameter between 10 nm and 900 nm. More preferably, the particles have a mass median aerodynamic diameter between 10 nm and 800 nm, 10 nm and 700 nm, 10 nm and 600 nm, 10 nm and 500 nm, 10 nm and 400 nm, 10 nm and 300 nm, 10 nm and 200 nm, or 10 nm and 100 nm.
Methods And Devices For Sustained In-Vivo Release Of An Active Agent
US Patent:
2006008, Apr 27, 2006
Filed:
Sep 27, 2005
Appl. No.:
11/238104
Inventors:
John Higuchi - Salt Lake City UT, US
S. Li - Salt Lake City UT, US
William Higuchi - Salt Lake City UT, US
Daniel Mufson - Napa CA, US
Michael Delmage - Napa CA, US
Anthony Tuitupou - Tooele UT, US
S. Li - Salt Lake City UT, US
William Higuchi - Salt Lake City UT, US
Daniel Mufson - Napa CA, US
Michael Delmage - Napa CA, US
Anthony Tuitupou - Tooele UT, US
International Classification:
A61N 1/30
US Classification:
604020000
Abstract:
The present invention includes methods and devices for providing sustained in-vivo release of an active agent to a subject. In some aspects, such release may be achieved by reacting an active agent in-vivo with a depot forming agent in order to form a sustained release active agent depot inside the subject. The depot can then release the active agent over a sustained period of time.
Isbn (Books And Publications)
Reza Abdoh
Author:
Daniel Mufson
ISBN #:
0801861233
Reza Abdoh
Author:
Daniel Mufson
ISBN #:
0801861241
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