Daniel C Py1 Helena Ave, Larchmont, NY 10538

6505622, Jan 14, 2003

Aug 9, 2001

09/927272

Daniel Py - Larchmont NY, 10538

A61M 1508

12820318, 12820328, 12820322, 12820718

A pump-type dispenser for dispensing predetermined doses of medicament in droplets or in spray form to the nasal area incorporates a rigid vial for medicament, an expandable pouch located within the rigid vial, a nasal screen, a one-way actuation mechanism, a one-way valve mechanism in the nozzle area and a spring element, both the valve mechanism and the spring element being formed as integral portions of the pump body. The one-way valve mechanism in the nozzle area ensures a one-way movement of medicament from the dispenser, thereby preserving substantially perfect sterility of the medicament in the dispenser, without requiring the use of preservatives. The one-way actuation mechanism enables the user to load and dispense a uniform quantity of medicament with a uniform actuation force and speed via a single continuous motion of the actuation mechanism. The rigid vial/expandable-pouch combination facilitates improved long term use, as well as uniformity of dosage independent of the pump orientation.

6604561, Aug 12, 2003

Feb 12, 2001

09/781846

Daniel Py - Larchmont NY

Medical Instill Technologies, Inc. - Stamford CT

B65B 104

141329, 141 59, 141 82, 215247, 215355, 604415

A resealable cap for a medicament vial has a base portion formed of vulcanized rubber or like material known for providing a stable environment for the medicament contained within the vial, and a resealable portion overlying the base portion. The resealable portion is made of low-density polyethylene or like material, and can be punctured by a needle or like injection member for dispensing medicament into the vial. Prior to filling, the cap is assembled to the vial and the cap/vial assembly is sterilized. Then, a needle is inserted through the cap and medicament is introduced through the needle and into the vial. Upon withdrawal of the needle, the penetrated region of the cap is fused by laser or direct heat sealing to hermetically seal the needle hole in the cap.

D485365, Jan 13, 2004

Sep 3, 2002

29/166810

Daniel Py - Stamford CT
Norbert M. Assion - Shelton CT
Julian V. Chan - Spring Valley NY
Jacques Thilly - Rixensart, BE
Christian Vandecasserie - Rixensart, BE

Medical Instill Technologies, Inc. - Stamford CT
GlaxoSmithKline Biologicals s.a. - Rixensart

2402

D24224, D24121

6684916, Feb 3, 2004

Mar 21, 2003

10/393966

Daniel Py - Larchmont NY

Medical Instill Technologies, Inc. - Stamford CT

B65B 304

141 2, 141 82, 141 85, 141 94, 141284, 141329, 141285, 53403

A resealable cap for a medicament vial has a base portion formed of vulcanized rubber or like material known for providing a stable environment for the medicament contained within the vial, and a resealable portion overlying the base portion. The resealable portion is made of low-density polyethylene or like material, and can be punctured by a needle or like injection member for dispensing medicament into the vial. Prior to filling, the cap is assembled to the vial and the cap/vial assembly is sterilized. Then, a needle is inserted through the cap and medicament is introduced through the needle and into the vial. Upon withdrawal of the needle, the penetrated region of the cap is fused by laser or direct heat sealing to hermetically seal the needle hole in the cap.

6685109, Feb 3, 2004

Sep 24, 2001

09/962949

Daniel Py - Larchmont NY, 10538

B05B 134

239461, 239333, 239451, 239460, 2395331, 239490, 239491

An aerosol tip mechanism for an aerosol-type dispenser for dispensing liquid content has a flexible outer shell, a rigid cap portion composed of lower and upper portions, and a rigid nozzle portion having a rigid shaft received within the outlet portion of the flexible outer shell. The rigid shaft interfaces the outlet portion of the outer shell, forming a first normally-closed one-way valve. The lower and upper portions of the rigid cap portion form boots adapted to receive an outlet portion of the flexible outer shell, the boots thereby constraining a lateral motion of the outlet portion of the outer shell, and symmetrically centering the outlet portion around the rigid shaft of the nozzle. The rigid nozzle portion includes a plurality of liquid channels for delivering liquid from a reservoir to a swirling chamber defined within the rigid cap portion, which liquid channels are configured to minimize energy losses of the liquid and promote a more homogeneous fluid particle size in the dispensed aerosol. The aerosol tip mechanism provides for long-term sterility of the stored fluid, which in turn allows for preservation of the sterility of non-chemically preserved formulations, which may be in the form of suspension or liquid gels.

6739636, May 25, 2004

May 2, 2002

10/139192

Daniel Py - Stamford CT

Medical Instill Technologies, Inc. - Stamford CT

A61F 900

294 12, 206 51

A contact lens applicator has an elongated housing defining an interior chamber for storing contact lenses, first and second triggers mounted on the housing, a depressor for depressing each eyelid where the depressor is drivingly coupled to the triggers, a pair of opposing wing-shaped members projecting outwardly from opposite sides of the rollers for providing a support surface for facilitating locating the apparatus over the eye, and a pusher assembly slidably mounted within the interior chamber for engaging a contact lens holder and applying a contact lens thereon to the eye when the triggers are actuated. The contact lens is stored in a cartridge within the elongated housing. The lens holder is movable within the cartridge upon actuating the pusher, and includes a predetermined amount of saline or other solution for defining appropriate conditions for storing the lens.

D492192, Jun 29, 2004

Oct 21, 2002

29/169537

Daniel Py - Stamford CT
Julian V. Chan - Spring Valley NY
Catalina M. Aranyi - Easton CT

Medical Instill Technologies, Inc. - Stamford CT

0901

D 9300

6761286, Jul 13, 2004

Oct 23, 2001

10/001745

Daniel Py - Larchmont NY
Joseph M. Ting - Fairfield CT

Medical Instill Technologies, Inc. - Stamford CT

B65D 3556

222105, 2223216, 2223865

A dispenser for dispensing a fluid includes a rigid vial that has a main fluid chamber containing a fluid, and a pump assembly that is in fluid communication with the main fluid chamber and is configured to dispense a predetermined quantity of fluid from the main fluid chamber. A flexible bladder is provided which is located within the main fluid chamber and is configured to expand to fill the ullage created within the main fluid chamber during dispensing of fluid by the pump assembly. The resilient bladder tends to force itself outwardly toward the rigid vial and, in turn, increases the pressure within the main fluid chamber in comparison to the interior of the bladder to thereby prevent the ingress of air or vapors through the bladder or otherwise into the main fluid chamber.