Career records & work history
Medicine Doctors
David Navarre Reifsnyder
Specialties:
Internal Medicine
Infectious Disease
Infectious Disease
Education:
Columbia University (1963) Internal Medicine
David T Reifsnyder Deceased19 Pueblo Dr, San Rafael, CA 94903
David Reifsnyder Phones & Addresses
19 Pueblo Dr, San Rafael, CA 94903
Azusa, CA
West Covina, CA
Novato, CA
Azusa, CA
Social networks
David T Reifsnyder
Linkedin
Mentions for David T Reifsnyder
David Reifsnyder resumes & CV records
Resumes
David Reifsnyder
Publications & IP owners
Us Patents
Method Of Purifying Tfpi And Tfpi Analogs
US Patent:
7851433, Dec 14, 2010
Filed:
Jan 8, 2004
Appl. No.:
10/753078
Inventors:
David H. Reifsnyder - El Cerrito CA, US
Duane Inlow - Alamo CA, US
Glenn Dorin - San Rafael CA, US
Patricio T. Riquelme - Walnut Creek CA, US
Cynthia A. Cowgill - Berkeley CA, US
Douglas G. Bolesch - Berkeley CA, US
Mark E. Gustafson - St. Charles MO, US
Duane Inlow - Alamo CA, US
Glenn Dorin - San Rafael CA, US
Patricio T. Riquelme - Walnut Creek CA, US
Cynthia A. Cowgill - Berkeley CA, US
Douglas G. Bolesch - Berkeley CA, US
Mark E. Gustafson - St. Charles MO, US
Assignee:
Novartis Vaccines and Diagnostics, Inc. - Emeryville CA
Pharmacia & Upjohn Company - Kalamazoo MI
Pharmacia & Upjohn Company - Kalamazoo MI
International Classification:
C07K 14/00
US Classification:
514 2, 530350
Abstract:
Highly purified preparations of TFPI or TFPI analogs can be prepared using a method that generally involves the following steps: (1) expression of TFPI or TFPI analog in , (2) isolation of refractile bodies, (3) dissolution of the refractile bodies and refolding of the expressed TFPI or TFPI analog, (4) SP-Sepharose fast flow (FF) chromatography, (5) a first concentration and diafiltration step, (6) Q-Sepharose high (HP) performance chromatography, (7) butyl hydrophobic interaction chromatography (HIC), (8) SP-Sepharose HP chromatography, and (9) a second concentration/diafiltration step. Less than about 12% of the TFPI or TFPI analog molecules in such preparations are modified TFPI or TFPI analog species (i. e. , oxidized, carbamylated, acetylated, deamidated, aggregated, or misfolded species).
Purification Of Molecules
US Patent:
6265542, Jul 24, 2001
Filed:
Oct 8, 1998
Appl. No.:
9/168548
Inventors:
Robert Lee Fahrner - San Francisco CA
David Reifsnyder - El Cerrito CA
David Reifsnyder - El Cerrito CA
Assignee:
Genentech, Inc. - South San Francisco CA
International Classification:
C07K 114
C07K 116
C07K 116
US Classification:
530344
Abstract:
A process for purifying molecules from contaminants is provided. In this process a mixture containing the molecule (peptide, polypeptide, or biologically active non-peptidyl compound) and its contaminants is loaded onto a reversed-phase liquid chromatography column and the molecule is eluted from the column with a buffer containing hexylene glycol.
NOTICE: You may not use PeopleBackgroundCheck or the information it provides to make decisions about employment, credit, housing or any other purpose that would require Fair Credit Reporting Act (FCRA) compliance. PeopleBackgroundCheck is not a Consumer Reporting Agency (CRA) as defined by the FCRA and does not provide consumer reports.