Eric R Gundersen, Age 5054 Sunset Trl, Denville, NJ 07834

6800654, Oct 5, 2004

Jun 13, 2002

10/171041

Scott Christian Mayer - Bridgewater NJ
Eric Gould Gundersen - Hightstown NJ
Hassan Mahmoud Elokdah - Yardley PA
David LeRoy Crandall - Doylestown PA

Wyeth - Madison NJ

C07D20904

514381, 548252, 548243, 548413, 548414, 548491, 549356, 549414, 514414, 514415

This invention provides PAI-1 inhibiting compounds of Formula I: wherein: R , R , R , and R are eachH, alkyl,, alkanoyl, halo, OH, aryl optionally substituted with R , perfluoroalkyl, alkoxy, amino, alkylamino, dialkylamino, perfluoroalkoxy; R is H, alkyl, perfluoroalkyl, aryl optionally substituted with R , alkanoyl, aroyl optionally substituted with R ; R is H, alkyl, alkylaryl, benzyl optionally substituted with R , alkanoyl, aroyl optionally substituted with R ; R is H, alkyl, alkylaryl, aryl optionally substituted with R ; n is 0-6; A is COOH, or an acid mimic such as tetraazole, SO H, PO H , tetronic acid, etc. ; R is H, alkyl, cycloalkyl, alkanoyl, halo, OH, perfluoroalkyl, alkoxy, amino, alkylamino, dialkylamino, perfluoroalkoxy; or a pharmaceutically acceptable salt thereof; as well as pharmaceutical compositions and methods of treatment using these compounds.

6939886, Sep 6, 2005

Jul 20, 2004

10/894618

Scott Christian Mayer - Bridgewater NJ, US
Eric Gould Gundersen - Royersford PA, US
Hassan Mahmoud Elokdah - Yardley PA, US
David LeRoy Crandall - Doylestown PA, US

Wyeth - Madison NJ

A61K031/404
C07D209/04
C07D403/02

514381, 548243, 548252, 548413, 548414, 548491, 549356, 549414, 514414, 514415

This invention provides PAI-1 inhibiting compounds of Formula I: wherein: R, R, R, and Rare each H, alkyl, alkanoyl, halo, OH, aryl optionally substituted with R, perfluoroalkyl, alkoxy, amino, alkylamino, dialkylamino, perfluoroalkoxy; Ris H, alkyl, perfluoroalkyl, aryl optionally substituted with R, alkanoyl, aroyl optionally substituted with R; Ris H, alkyl, alkylaryl, benzyl optionally substituted with R, alkanoyl, aroyl optionally substituted with R; Ris H, alkyl, alkylaryl, aryl optionally substituted with R; n is 0-6; A is COOH, or an acid mimic such as tetraazole, SOH, POH, tetronic acid, etc. ; Ris H, alkyl, cycloalkyl, alkanoyl, halo, OH, perfluoroalkyl, alkoxy, amino, alkylamino, dialkylamino, perfluoroalkoxy; or a pharmaceutically acceptable salt thereof; as well as pharmaceutical compositions and methods of treatment using these compounds.

7342039, Mar 11, 2008

Sep 23, 2004

10/947846

Lisa Marie Havran - Florence NJ, US
John Anthony Butera - Clarksburg NJ, US
Hassan Mahmoud Elokdah - Yardley PA, US
Douglas John Jenkins - Collegeville PA, US
Eric Gould Gundersen - Royersford PA, US

Wyeth - Madison NJ

A61K 31/404
C07D 209/04

514415, 548469, 548490, 548491, 548146, 548182, 548215, 548229, 548125, 548129, 548132, 548250, 548252, 548240, 548243, 5482622, 5483647, 514361, 514364, 514372, 514381

The present invention relates to substituted indole oximes and methods of using them.

7351730, Apr 1, 2008

Jun 22, 2005

11/158881

Scott Christian Mayer - Bridgewater NJ, US
Eric Gould Gundersen - Royersford PA, US
Hassan Mahmoud Elokdah - Yardley PA, US
David LeRoy Crandall - Doylestown PA, US

Wyeth - Madison NJ

A61K 31/404
C07D 209/04
C07D 403/02

514381, 548243, 548252, 548413, 548414, 548491, 549356, 549414, 514414, 514415

This invention provides PAI-1 inhibiting compounds of Formula I:.

7420083, Sep 2, 2008

Sep 23, 2004

10/948611

Lisa Marie Havran - Florence NJ, US
John Anthony Butera - Clarksburg NJ, US
Hassan Mahmoud Elokdah - Yardley PA, US
Douglas John Jenkins - Collegeville PA, US
Eric Gould Gundersen - Royersford PA, US

Wyeth - Madison NJ

C07C 63/06
A61K 31/19

562440, 514568, 514570

The present invention relates to substituted aryl oximes and methods of using them.

5780505, Jul 14, 1998

Jul 7, 1997

8/889166

Madelene M. Antane - Lawrenceville NJ
David R. Herbst - Wayne PA
Geraldine R. McFarlane - Monmouth Junction NJ
Eric G. Gundersen - Plainsboro NJ
Bradford H. Hirth - Littleton MA
Dominick A. Quagliato - Bridgewater NJ
Russell F. Graceffa - Plainsboro NJ
John A. Butera - Clarksburg NJ

American Home Products Corporation - Madison NJ

A61K 31275

514522

The compounds of the formula: ##STR1## wherein R. sub. 1 is straight chain alkyl, branched chain alkyl, cycloalkyl, hydroxyalkyl, fluoroalkyl or polyfluoroalkyl; R. sub. 7 and R. sub. 8 are, independently, hydrogen or an acyl substituent selected from the group consisting of formyl, alkanoyl, alkenoyl, alkoxycarbonyl, alkylsulfonyl, aroyl, arylalkenoyl, arylsulfonyl, arylalkanoyl or arylalkylsulfonyl; A is a phenyl group with either two or three substituents of the following formula: ##STR2## wherein the positions of substitution are R. sub. 2,R. sub. 3 -, R. sub. 2,R. sub. 4 -, R. sub. 2,R. sub. 5 -, R. sub. 2,R. sub. 6 -, R. sub. 3,R. sub. 4 -, R. sub. 3,R. sub. 5 -, and R. sub. 2,R. sub. 4,R. sub. 6 - and R. sub. 2 is methyl, ethyl, fluoro, chloro, methoxy or trifluoromethyl; R. sub. 3 is methyl, ethyl, fluoro, chloro, methoxy or trifluoromethyl; R. sub.

5763474, Jun 9, 1998

Jul 7, 1997

8/889164

David R. Herbst - Wayne PA
Madelene M. Antane - Lawrenceville NJ
Geraldine R. McFarlane - Monmouth Junction NJ
Eric G. Gundersen - Plainsboro NJ
Bradford H. Hirth - Littleton MA
Dominick A. Quagliato - Bridgewater NJ
Russell F. Graceffa - Plainsboro NJ
John A. Butera - Clarksburg NJ

American Home Products Corporation - Madison NJ

A61K 31135
A61K 31165
C07C22520
C07C23582

514399

The compounds of the formula: ##STR1## wherein R. sub. 1 is straight chain alkyl, branched chain alkyl cycloalkyl, hydroxyalkyl, fluoroalkyl or polyfluoroalkyl; R. sub. 2 and R. sub. 3 are, independently, hydrogen or an acyl substituent selected from the group consisting of formyl, alkanoyl, alkenoyl, alkoxycarbonyl, alkylsulfonyl, aroyl, arylalkenoyl, arylsulfonyl, arylalkanoyl or arylalkylsulfonyl; A is a substituted phenyl group of the following formula: ##STR2## wherein R. sub. 4 and R. sub. 5 are, independently, cyano, nitro, amino, alkyl, perfluoroalkyl, fluoroalkyl, alkoxy, perfluoroalkoxy, fluoroalkoxy, amino, alkylamino, dialkylamino, sulfamyl, alkylsulfonamido, arylsulfonamido, carbamoyl, alkylcarbamoyl, dialkylcarbamoyl, alkylcarboxamido, arylcarboxamido, alkylsulfonyl, perfluoroalkylsulfonyl, arylsulfonyl, chloro, bromo, fluoro, iodo, 1-imidazolyl, carboxyl or hydrogen, with the proviso that R. sub. 4 and R. sub. 5 cannot both be hydrogen; or a pharmaceutically acceptable salt thereof, relaxes smooth muscles.

2018003, Feb 1, 2018

Jul 20, 2017

15/655719

- Oberderdingen, DE
Bernd Becker - Kürnbach, DE
Eric Gundersen - Medford NJ, US

E03C 1/05
F16K 11/00
E03C 1/04

In order to provide a faucet comprising a base, a hose spray unit and an arm held on the base, wherein the arm comprises a hose spray unit receptacle on which the hose spray unit is releasably held in a rest position, wherein the passage of water through the hose spray unit is controllable particularly easily and rapidly by an operating person, it is proposed that the faucet comprises a sensor for detecting the presence and/or the movement of a hand of an operating person in a detection region of the sensor, wherein the sensor is arranged on the arm.