Eric R Gundersen, Age 49Parsippany, NJ

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Denville, NJ

33 Woodland Dr, Vernon, NJ 07462 (973) 827-3839 (973) 827-8619 (973) 827-3203

113 Drew Rd, Sussex, NJ 07461 (973) 209-4511 (973) 827-5605

32 Wits End Dr, Hamburg, NJ 07419 (973) 209-4511

Highland Lakes, NJ

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Erik Gundersen

Erik Gundersen (born 8 October 1959, in Esbjerg, Denmark was a speedway rider in the late 1970s and 1980s. Gundersen was the Speedway World Championship

Us Patents

2,3,5-Substituted Biphenyls Useful In The Treatment Of Insulin Resistance And Hyperglycemia

US Patent:
6451827, Sep 17, 2002
Filed:
Jan 26, 2001
Appl. No.:
09/771469
Inventors:
John A. Butera - Clarskburg NJ
Craig E. Caufield - New York NY
Russell F. Graceffa - Hampton NH
Alexander Greenfield - Princeton Junction NJ
Eric G. Gundersen - Plainsboro NJ
Lisa Marie Havran - Bordentown NJ
Alan H. Katz - Lawrenceville NJ
Joseph R. Lennox - Morrixville NC
Scott C. Mayer - Robbinsville NJ
Robert E. McDevitt - Somerset NJ
Assignee:
Wyeth - Madison NJ
International Classification:
A61K 3144
US Classification:
514357, 546300, 544162, 548217, 5483355, 548469, 549491, 5142378, 514375, 514399, 514415, 514471
Abstract:
This invention provides compounds of Formula I having the structure wherein: B, C, D, and R are as defined hereinbefore in the specification, or a pharmaceutically acceptable salt thereof, which are useful in treating metabolic disorders related to insulin resistance or hyperglycemia.

2,3,5-Substituted Biphenyls Useful In The Treatment Of Insulin Resistance And Hyperglycemia

US Patent:
6765021, Jul 20, 2004
Filed:
Aug 9, 2002
Appl. No.:
10/215438
Inventors:
John A. Butera - Clarkburg NJ
Craig E. Caufield - New York NY
Russell F. Graceffa - Hampton NH
Alexander Greenfield - Princeton Junction NJ
Eric G. Gundersen - Plainsboro NJ
Lisa Marie Havran - Bordentown NJ
Alan H. Katz - Lawrenceville NJ
Joseph R. Lennox - Morrisville NC
Scott C. Mayer - Robbinsville NJ
Robert E. McDevitt - Somerset NJ
Assignee:
Wyeth - Madison NJ
International Classification:
A61K 3117
US Classification:
514596, 564 48, 562457, 560 19, 560 43, 514572, 514485, 514476
Abstract:
This invention provides compounds of formula I having the structure wherein: B, D, C, and R as defined herein.

Substituted Naphthyl Indole Derivatives As Inhibitors Of Plasminogen Activator Inhibitor Type-1 (Pai-1)

US Patent:
6800654, Oct 5, 2004
Filed:
Jun 13, 2002
Appl. No.:
10/171041
Inventors:
Scott Christian Mayer - Bridgewater NJ
Eric Gould Gundersen - Hightstown NJ
Hassan Mahmoud Elokdah - Yardley PA
David LeRoy Crandall - Doylestown PA
Assignee:
Wyeth - Madison NJ
International Classification:
C07D20904
US Classification:
514381, 548252, 548243, 548413, 548414, 548491, 549356, 549414, 514414, 514415
Abstract:
This invention provides PAI-1 inhibiting compounds of Formula I: wherein: R , R , R , and R are eachH, alkyl,, alkanoyl, halo, OH, aryl optionally substituted with R , perfluoroalkyl, alkoxy, amino, alkylamino, dialkylamino, perfluoroalkoxy; R is H, alkyl, perfluoroalkyl, aryl optionally substituted with R , alkanoyl, aroyl optionally substituted with R ; R is H, alkyl, alkylaryl, benzyl optionally substituted with R , alkanoyl, aroyl optionally substituted with R ; R is H, alkyl, alkylaryl, aryl optionally substituted with R ; n is 0-6; A is COOH, or an acid mimic such as tetraazole, SO H, PO H , tetronic acid, etc. ; R is H, alkyl, cycloalkyl, alkanoyl, halo, OH, perfluoroalkyl, alkoxy, amino, alkylamino, dialkylamino, perfluoroalkoxy; or a pharmaceutically acceptable salt thereof; as well as pharmaceutical compositions and methods of treatment using these compounds.

Substituted Naphthyl Indole Derivatives As Inhibitors Of Plasminogen Activator Inhibitor Type-1 (Pai-1)

US Patent:
6939886, Sep 6, 2005
Filed:
Jul 20, 2004
Appl. No.:
10/894618
Inventors:
Scott Christian Mayer - Bridgewater NJ, US
Eric Gould Gundersen - Royersford PA, US
Hassan Mahmoud Elokdah - Yardley PA, US
David LeRoy Crandall - Doylestown PA, US
Assignee:
Wyeth - Madison NJ
International Classification:
A61K031/404
C07D209/04
C07D403/02
US Classification:
514381, 548243, 548252, 548413, 548414, 548491, 549356, 549414, 514414, 514415
Abstract:
This invention provides PAI-1 inhibiting compounds of Formula I: wherein: R, R, R, and Rare each H, alkyl, alkanoyl, halo, OH, aryl optionally substituted with R, perfluoroalkyl, alkoxy, amino, alkylamino, dialkylamino, perfluoroalkoxy; Ris H, alkyl, perfluoroalkyl, aryl optionally substituted with R, alkanoyl, aroyl optionally substituted with R; Ris H, alkyl, alkylaryl, benzyl optionally substituted with R, alkanoyl, aroyl optionally substituted with R; Ris H, alkyl, alkylaryl, aryl optionally substituted with R; n is 0-6; A is COOH, or an acid mimic such as tetraazole, SOH, POH, tetronic acid, etc. ; Ris H, alkyl, cycloalkyl, alkanoyl, halo, OH, perfluoroalkyl, alkoxy, amino, alkylamino, dialkylamino, perfluoroalkoxy; or a pharmaceutically acceptable salt thereof; as well as pharmaceutical compositions and methods of treatment using these compounds.

Substituted Naphthyl Indole Derivatives As Inhibitors Of Plasminogen Activator Inhibitor Type-1 (Pai-1)

US Patent:
7351730, Apr 1, 2008
Filed:
Jun 22, 2005
Appl. No.:
11/158881
Inventors:
Scott Christian Mayer - Bridgewater NJ, US
Eric Gould Gundersen - Royersford PA, US
Hassan Mahmoud Elokdah - Yardley PA, US
David LeRoy Crandall - Doylestown PA, US
Assignee:
Wyeth - Madison NJ
International Classification:
A61K 31/404
C07D 209/04
C07D 403/02
US Classification:
514381, 548243, 548252, 548413, 548414, 548491, 549356, 549414, 514414, 514415
Abstract:
This invention provides PAI-1 inhibiting compounds of Formula I:.

2,3,5-Substituted Biphenyls Useful In The Treatment Of Insulin Resistance And Hyperglycemia

US Patent:
6214877, Apr 10, 2001
Filed:
May 10, 1999
Appl. No.:
9/307850
Inventors:
John A. Butera - Clarskburg NJ
Craig E. Caufield - New York NY
Russell F. Graceffa - Hampton NH
Alexander Greenfield - Princeton Junction NJ
Eric G. Gundersen - Plainsboro NJ
Lisa Marie Havran - Bordentown NJ
Alan H. Katz - Lawrenceville NJ
Joseph R. Lennox - Morrixville NC
Scott C. Mayer - Robbinsville NJ
Robert E. McDevitt - Somerset NJ
International Classification:
A61K 31166
C07C23544
US Classification:
514563
Abstract:
This invention provides compounds of Formula I having the structure ##STR1## wherein: B, C, D, and R. sup. 1 are as defined hereinbefore in the specification, or a pharmaceutically acceptable salt thereof, which are useful in treating metabolic disorders related to insulin resistance or hyperglycemia.

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