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Erik M Schaefer, Age 6512 Greystone Ln, Hopkinton, MA 01748

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Known as:
Erik Michael Schaefer Erik W Schaefer Erik M Schaeffer Erik Shaefer Eric Schaeffer
Related to:
Mark Schaeffer

Erik Schaefer Phones & Addresses

12 Greystone Ln, Hopkinton, MA 01748 (508) 435-5548

2 Lilac Ct, Hopkinton, MA 01748

Brooklyn, NY

Fitchburg, WI

Ypsilanti, MI

Houston, TX

Fort Worth, TX

Woodstock, NY

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Work

Company: Thermo fisher scientific tmo 2010 Position: Lhc global r&d director

Education

School / High School: University of Vermont College of Medicine- Burlington, VT 1988 Specialities: Doctor of Philosophy in Microbiology & Molecular Genetics

Skills

R&D and Technology Management in life science industry New product development (NPD) across disciplines including engineering • injection molding • biology • chemistry/biochemistry • translational biomarkers • sample preparation and assay development (molecular • proteomic • antibody & cell-based formats) . Creating innovative work flow solutions (instruments • software • consumable plastic or immune and analytical chemistry devices • reagents or kits). Phenotype assessments including creating and characterizing physiologically-relevant cell culture systems and transgenic animal models of disease. Style: High energy and commitment to strong science (internally & working with external thought leaders) and strategic and tactical decision making • clear communication and operational excellence to deliver high-value products that enable basic research • drug discovery or diagnostics to improve human health and drive business performance. In-depth knowledge across scientific disciplines (signal transduction • cell and stem cell biology phenotypes as model cell systems • biochemical and cell-based assays • and transgenic animal models of disease. Strategic Planning (3-5-yr plans) VOC & Customer Observations (IDEO) Project • Program & Portfolio Management • including evaluation of modern PPM software Innovation • Technology and New Product Development Roadmaps & Prioritization Design Control and execution with Phase-gate Product Development Frameworks Software: Agile • Oracle/Enterprise-one • COGNOS (sales) • Microsoft (Outlook • Excel • PowerPoint & Project) Situational Leadership Cross-site • Cross-functional & High-Performing Team Development Human Resource & Succession Planning • GAP Analysis • Performance Management • Ethics Legal Contract Negotiations • NDAs • Collaborative Agreements • Intellectual Property Rights (IPR) & IP Portfolio Mgmt. Continuous improvement via Six Sigma • Lean • PPI • Risk Assessment • DFMEA • PFMEA • Corrective & Preventive Action (CAPA) Compliance: Design Control • Document Version Control (Agile) • ISO 9001 • ISO 13485 • CE & CE-IVD mark

Mentions for Erik M Schaefer

Erik Schaefer resumes & CV records

Resumes

Erik Schaefer Photo 38

Co-Founder, President And Chief Scientific Officer At Assayquant Technologies, Inc

Location:
Hopkinton, MA
Industry:
Biotechnology
Work:
Assayquant Technologies
Co-Founder, President and Chief Scientific Officer at Assayquant Technologies, Inc Thermo Fisher Scientific Nov 2010 - Jan 2015
Global R and D Director, Liquid Handling, Sample Preparation and Analysis and Consumables Business Unit Meso Scale Diagnostics, Llc. Aug 2010 - Oct 2010
Director, External Scientific Affairs Milliporesigma May 2009 - Dec 2009
Leader, Collaborative Alliances and Innovation Strategy Life Technologies Nov 2005 - Jan 2009
Site Director, Signal Transduction Research Center Biosource International 1998 - 2005
Vice President, R and D Signal Transduction Promega Apr 1994 - Jan 1998
Group Leader, R and D Signal Transduction Texas A&M University Jan 1988 - Apr 1994
Research Scientist and Hhmi Fellow
Education:
The Robert Larner, M.d. College of Medicine at the University of Vermont 1982 - 1988
Doctorates, Doctor of Philosophy, Biology, Microbiology, Biochemistry University of Maine 1978 - 1981
Bachelors, Bachelor of Arts, Zoology, Biochemistry Onteora Central High School 1975 - 1978
Skills:
Immunoassays, Drug Discovery, Cell Biology, Cell Culture, Life Sciences, Cell Based Assays, Biochemistry, Cell, Protein Chemistry, Elisa, Molecular Biology, Pcr, Immunology, Biotechnology, Qpcr, Technology Transfer, Protein Purification, Neuroscience, Oncology, Proteomics, Stem Cells, Immunohistochemistry, Fluorescence, Tissue Culture, In Vivo, Genomics, Antibodies, Lifesciences, Assay Development, Work Flow Solutions, Instrument Systems, R&D, Biomarker Discovery, Biomarkers, Biopharmaceuticals, Commercialization, Drug Development, Laboratory, Pharmaceutical Industry, Science, Strategy, Research and Development, Polymerase Chain Reaction, Real Time Polymerase Chain Reaction
Interests:
Development
New Product Development
Fly Fishing
Skiing
Economic Empowerment
Collaboration and Presentations
Hiking
Biking
Collaboration
New Productdevelopment
Presentations
Collaboration Andpresentations
Travel
New Product
Scientific Discovery
Languages:
German
Erik Schaefer Photo 39

Nuclear Product Specialist

Work:

Nuclear Product Specialist
Erik Schaefer Photo 40

Erik Schaefer

Erik Schaefer Photo 41

Erik Schaefer

Location:
United States
Erik Schaefer Photo 42

Erik Schaefer - Hopkinton, MA

Work:
THERMO FISHER SCIENTIFIC TMO 2010 to 2000
LHC Global R&D Director MILLIPORE CORPORATION - Danvers, MA 2009 to 2009
R&D Leader, Collaborative Alliances and Innovation Strategy INVITROGEN / LIFE TECHNOLOGIES LIFE - Hopkinton, MA 2005 to 2009
Site Director/R&D Leader BIOSOURCE INTERNATIONAL - Hopkinton, MA 1998 to 2005
Vice President, R&D PROMEGA CORPORATION - Madison, WI 1994 to 1998
R&D Group Leader
Education:
University of Vermont College of Medicine - Burlington, VT 1988
Doctor of Philosophy in Microbiology & Molecular Genetics University of Maine at Orono - Orono, ME 1981
Bachelor of Arts in Zoology, Minor in Chemistry/Biochemistry
Skills:
R&D and Technology Management in life science industry New product development (NPD) across disciplines including engineering, injection molding, biology, chemistry/biochemistry, translational biomarkers, sample preparation and assay development (molecular, proteomic, antibody & cell-based formats) . Creating innovative work flow solutions (instruments, software, consumable plastic or immune and analytical chemistry devices, reagents or kits). Phenotype assessments including creating and characterizing physiologically-relevant cell culture systems and transgenic animal models of disease. Style: High energy and commitment to strong science (internally & working with external thought leaders) and strategic and tactical decision making, clear communication and operational excellence to deliver high-value products that enable basic research, drug discovery or diagnostics to improve human health and drive business performance. In-depth knowledge across scientific disciplines (signal transduction, cell and stem cell biology phenotypes as model cell systems, biochemical and cell-based assays, and transgenic animal models of disease. Strategic Planning (3-5-yr plans) VOC & Customer Observations (IDEO) Project, Program & Portfolio Management, including evaluation of modern PPM software Innovation, Technology and New Product Development Roadmaps & Prioritization Design Control and execution with Phase-gate Product Development Frameworks Software: Agile, Oracle/Enterprise-one, COGNOS (sales), Microsoft (Outlook, Excel, PowerPoint & Project) Situational Leadership Cross-site, Cross-functional & High-Performing Team Development Human Resource & Succession Planning, GAP Analysis, Performance Management, Ethics Legal Contract Negotiations, NDAs, Collaborative Agreements, Intellectual Property Rights (IPR) & IP Portfolio Mgmt. Continuous improvement via Six Sigma, Lean, PPI, Risk Assessment, DFMEA, PFMEA, Corrective & Preventive Action (CAPA) Compliance: Design Control, Document Version Control (Agile), ISO 9001, ISO 13485, CE & CE-IVD mark

Publications & IP owners

Us Patents

Method For Quantifying Phosphokinase Activity On Proteins

US Patent:
8114617, Feb 14, 2012
Filed:
Dec 16, 2010
Appl. No.:
12/970250
Inventors:
Kevin J. Reagan - Agoura Hills CA, US
Erik Schaefer - Hopkinton MA, US
Jimin Wang - Thousand Oaks CA, US
Assignee:
Life Technologies Corporation - Carlsbad CA
International Classification:
G01N 33/53
G01N 33/543
US Classification:
435 721, 435 71, 436501, 436512, 436518, 436540
Abstract:
The invention involves a method for measuring phosphorylation of proteins at specific sites and, as such, is an indicator of the protein kinase activity of enzymes capable of phosphorylating those sites. The method involves the in vitro or in vivo phosphorylation of a target protein at a specific serine, threonine or tyrosine residue, subjecting that protein (non-phosphorylated) to reaction mixture containing all reagents, including phosphokinase which allow the creation of a phosphorylated form of protein. The phosphorylated protein is measured by contacting it with an antibody specific for the phosphorylation site(s). The invention includes antibodies useful in practicing the methods of the invention. The invention particularly relates to all proteins modified by phosphorylation and dephosphorylation as illustrated by Tau, Rb and EGFR proteins and antibodies specific for the site of phosphorylation of the Tau, Rb or EGFR proteins.

Method For Quantifying Phosphokinase Activity On Proteins

US Patent:
2003016, Aug 28, 2003
Filed:
Sep 7, 2001
Appl. No.:
09/948972
Inventors:
Kevin Reagan - Agoura Hills CA, US
Erik Schaefer - Hopkinton MA, US
Jimin Wang - Thousand Oaks CA, US
International Classification:
G01N033/53
US Classification:
435/007400
Abstract:
The invention involves a method for measuring phosphorylation of proteins at specific sites and, as such, is an indicator of the protein kinase activity of enzymes capable of phosphorylating those sites. The method involves the in vitro or in vivo phosphorylation of a target protein at a specific serine, threonine or tyrosine residue, subjecting that protein (non-phosphorylated) to reaction mixture containing all reagents, including phosphokinase which allow the creation of a phosphorylated form of protein. The phosphorylated protein is measured by contacting it with an antibody specific for the phosphorylation site(s). The invention includes antibodies useful in practicing the methods of the invention. The invention particularly relates to all proteins modified by phosphorylation and dephosphorylation as illustrated by Tau, Rb and EGFR proteins and antibodies specific for the site of phosphorylation of the Tau, Rb or EGFR proteins.

Methods For Measuring Real Time Kinase Activity

US Patent:
2007019, Aug 23, 2007
Filed:
Jan 18, 2007
Appl. No.:
11/624686
Inventors:
Kyle Gee - Springfield OR, US
Min Li - Brookline MA, US
Xiao-Dong Qian - Wellesley MA, US
Erik Schaefer - Hopkinton MA, US
Assignee:
INVITROGEN CORPORATION - Carlsbad CA
International Classification:
G01N 33/53
C07K 16/46
US Classification:
435007100, 530391100, 530409000
Abstract:
The present invention relates to methods for detecting and/or measuring the activity of a specific kinase, with the methods comprising contacting one or more kinases with a binding agent to isolate a specific kinase of interest. The isolated kinase is then contacted with a kinase activity sensor, where the kinase activity sensor is comprised of a kinase recognition motif that is capable of being recognized by the isolated kinase, and at least one phosphorylation site. The isolated kinase phosphorylates the amino acid target of the kinase activity sensor and levels of the phosphorylated target amino acid can then be quantified.

Method For Quantifying Phosphokinase Activity On Proteins

US Patent:
2009010, Apr 23, 2009
Filed:
Jul 24, 2008
Appl. No.:
12/179526
Inventors:
Kevin J. REAGAN - Agoura Hills CA, US
Erik Schaefer - Hopkinton MA, US
Jimin Wang - Newbury Park CA, US
Assignee:
INVITROGEN CORPORATION - Carlsbad CA
International Classification:
G01N 33/573
C07K 16/40
US Classification:
435 74, 5303879
Abstract:
The invention involves a method for measuring phosphorylation of proteins at specific sites and, as such, is an indicator of the protein kinase activity of enzymes capable of phosphorylating those sites. The method involves the in vitro or in vivo phosphorylation of a target protein at a specific serine, threonine or tyrosine residue, subjecting that protein (non-phosphorylated) to reaction mixture containing all reagents, including phosphokinase which allow the creation of a phosphorylated form of protein. The phosphorylated protein is measured by contacting it with an antibody specific for the phosphorylation site(s). The invention includes antibodies useful in practicing the methods of the invention. The invention particularly relates to all proteins modified by phosphorylation and dephosphorylation as illustrated by Tau, Rb and EGFR proteins and antibodies specific for the site of phosphorylation of the Tau, Rb or EGFR proteins.

Method For Quantifying Phosphokinase Activity On Proteins

US Patent:
2012013, May 31, 2012
Filed:
Sep 26, 2011
Appl. No.:
13/245045
Inventors:
Kevin J. Reagan - Agoura Hills CA, US
Erik Schaefer - Hopkinton MA, US
Jimin Wang - Newbury Park CA, US
Assignee:
LIFE TECHNOLOGIES CORPORATION - Carlsbad CA
International Classification:
G01N 33/566
C07K 16/18
US Classification:
435 792, 435 71, 5303898, 5303879
Abstract:
The invention involves a method for measuring phosphorylation of proteins at specific sites and, as such, is an indicator of the protein kinase activity of enzymes capable of phosphorylating those sites. The method involves the in vitro or in vivo phosphorylation of a target protein at a specific serine, threonine or tyrosine residue, subjecting that protein (non-phosphorylated) to reaction mixture containing all reagents, including phosphokinase which allow the creation of a phosphorylated form of protein. The phosphorylated protein is measured by contacting it with an antibody specific for the phosphorylation site(s). The invention includes antibodies useful in practicing the methods of the invention. The invention particularly relates to all proteins modified by phosphorylation and dephosphorylation as illustrated by Tau, Rb and EGFR proteins and antibodies specific for the site of phosphorylation of the Tau, Rb or EGFR proteins.

Possible Relatives

David W Schaefer  Dawn E Schaefer  Dean F Schaefer  Deanna M Schaefer  Dale G Schaefer  Dee A Schaefer  Derek D Schaefer  Erik A White  Erik M Stanger  Erik A Stanley 

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