Gary S Kath, Age 702671 Skytop Dr, Scotch Plains, NJ 07076

6449827, Sep 17, 2002

Oct 10, 2000

09/686645

Glenn A. Clarke - Flemington NJ
Marc N. Feiglin - East Brunswick NJ
Gary S. Kath - Scotch Plains NJ
Gregory W. King - Carteret NJ

Merck Co., Inc - Rahway NJ

B23Q 700

29559, 29283, 269303, 269309, 269318

An apparatus suitable for securely gripping and holding a microplate or other containers during robotic de-lidding operations. A microplate placed on the apparatus is held by a vacuum drawn through the base thereof, allowing the lid of the microplate to be removed without movement of the plate. Afterwards, the vacuum can be discontinued and the plate removed from the apparatus.

6461345, Oct 8, 2002

Nov 9, 1999

09/436416

Gary S. Kath - Scotch Plains NJ

Merck Co., Inc. - Rahway NJ

A61B 1900

604403, 251 4, 215247

There is disclosed a pinch valve for allowing access to a sterile reaction vessel using a cannula. The valve remains closed until a cannula is inserted. Upon removal of the cannula, the valve automatically closes maintaining the sterile or otherwise controlled conditions of the reaction vessel.

6736783, May 18, 2004

Mar 14, 2001

09/808449

Kevin R. Blake - Green Brook NJ
Kang Cheng - Bridgewater NJ
Glenn A. Clarke - Flemington NJ
Gary S. Kath - Scotch Plains NJ
Gregory W. King - Carteret NJ

Merck Co., Inc. - Rahway NJ

A61B 500

600582, 604327, 600575

An apparatus and process for automatically, repetitively sampling blood from conscious animals. The apparatus can simultaneously extract blood from a number of conscious, catherized animals at programmable time intervals. The apparatus is characterized as a system of computer controlled valves and pumps connected by tubing filled with saline solution to a catherized animal. Blood samples are collected via a cannula from the animal and placed in a fraction collector for analyses.

7276206, Oct 2, 2007

Jul 12, 2002

10/483467

Paul R. Augustine - Carteret NJ, US
Randal M. Bugianesi - Bridgewater NJ, US
Gary S. Kath - Scotch Plains NJ, US
Owen B. McManus - Skillman NJ, US
Paul B. Bennett - Doylestown PA, US
Tina A. Garyantes - Warren NJ, US
John P. Imredy - Lansdale PA, US

Merck & Co., Inc. - Rahway NJ

G01N 21/64
G01N 35/00
G01R 27/00

422 55, 324600, 422 50, 422 67, 436 43

Methods of identifying activators and inhibitors of voltage-gated ion channels are provided in which the methods employ electrical field stimulation of the cells in order to manipulate the open/close state transition of the voltage-gated ion channels. This allows for more convenient, more precise experimental manipulation of these transitions, and, coupled with efficient methods of detecting the result of ion flux through the channels, provides methods that are especially suitable for high throughput screening.

7735366, Jun 15, 2010

May 6, 2006

10/536120

Gary S. Kath - Scotch Plains NJ, US
Michael K. Wismer - Rahway NJ, US
Paul R. Augustine - Carteret NJ, US
Cordelia G. Rasa - Edison NJ, US

Merck Sharp & Dohme Corp. - Rahway NJ

G01N 9/10
G01G 5/00

73437, 33 1 V

Disclosed is an improved method for measuring the volume of an animal paw, suitable for use in a rat paw edema assay. Also disclosed is a novel apparatus for measuring the volume of liquid displaced by the insertion of an object into a liquid filled cup () which is on a cup holder basin (), the liquid filled cup and cup holder basin being inside a rectangular support assembly (), the measurement obtained by determining the buoyant force produced as a result of the displacement of the liquid by the animal paw.

2008031, Dec 25, 2008

Oct 7, 2005

11/664486

Claude Dufresne - East Brunswick NJ, US
Gary S. Kath - Scotch Plains NJ, US
Gregory W. King - Carteret NJ, US
Prakash S. Masurekar - Warren NJ, US
Salvatore J. Siciliano - East Brunswick NJ, US
Janet M. Sigmund - Cranford NJ, US
Neal R. Simpson - Frenchtown NJ, US
Stephen Skwish - East Brunswick NJ, US

MERCK & CO., INC. - Rahway NJ

C12M 1/26

4353091

This invention relates to an apparatus for streaking a sample on a media-coated (agar) plate in a predefined pattern utilizing a plate carousel system to house and retrieve a plate to a fixed location, a streaking mechanism having a floating stylus having a tip capable of gliding over the agar surface and depositing a sample onto the surface of the agar, a sample dispensing system and an optional wash station.

5882601, Mar 16, 1999

Jun 18, 1997

8/877986

Gary S. Kath - Scotch Plains NJ
Lihu Yang - Edison NJ
Gregory W. King - Carteret NJ

Merck & Co., Ltd. - Rhaway NJ

B01L 302

422102

An access port for a reaction or other fluid vessel which maintains the vessel under an inert gas atmosphere and maintains the integrity of the inert gas seal while performing filtered filling or draining operations is presented. The port uses a deflected septum sealing technique. The invention can be used for a number of laboratory and clinical operations on a variety of size and shape vessels. The combination of the appropriate vessel with this access port is very well suited for use in lab automation systems, such as automated solid phase chemical synthesis, biological screening, combinatorial chemistry and other areas where reaction chemistry is conducted.

5516491, May 14, 1996

Jul 28, 1994

8/281813

Gary S. Kath - Scotch Plains NJ
Gregory W. King - Carteret NJ
Kevin Chapman - Scotch Plains NJ

Merck & Co., Inc. - Rahway NJ

B01L 300

422102

A disposable transportable reactor vessel can be prepared by modifying an eye-dropper pipette. A HDPE plug is inserted in one end of the pipette to permit selective passage of fluid while preventing resin flow. The pipette is looped into the shape of a u-tube and inserted into a holder such that the pipette is axially aligned with the holder to facilitate use in a robotic system.