Gregory E Pietz, Age 5110508 1St Ave NW, Seattle, WA 98177

Gregory Pietz Phones & Addresses

10508 1St Ave NW, Seattle, WA 98177

Schofield, WI

330 Amoth Ct, Madison, WI 53704

Cleveland Heights, OH

Menomonee Falls, WI

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Gregory E Pietz

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Gregory Pietz Photo 10

Ncr-Iads Evaluator At Us Army, Test & Evaluation Command

Location:
United States
Industry:
Defense & Space

Publications & IP owners

Us Patents

Recombinant Production Of Polyanionic Polymers, And Uses Thereof

US Patent:
2005011, Jun 2, 2005
Filed:
Sep 14, 2004
Appl. No.:
10/939988
Inventors:
David Leung - Mercer Island WA, US
Philip Bergman - Mountlake Terrace WA, US
Alan Lofquist - Kirkland WA, US
Gregory Pietz - Seattle WA, US
Christopher Tompkins - Bothell WA, US
David Waggoner - Seattle WA, US
International Classification:
A61K038/20
A61K038/19
A61K038/21
A61K039/395
C07K014/535
C07K014/54
US Classification:
424085100, 424085700, 530351000, 424130100
Abstract:
A polyanionic polymer can improve the bioactivity and water-solubility properties of a drug to which it is joined. The inventive method provides a monodispersed preparation of a recombinantly-produced polyanionic polymer that can be easily manipulated, such as lengthened. An active moiety may be chemically or recombinantly joined to a polyanionic polymer to increase its biological half-life and/or solubility. The instant invention also provides a method for targeting the delivery of a polyanionic polymer conjugate or fusion protein to a specific cell type or tissue.

Recombinant Production Of Polyanionic Polymers, And Uses Thereof

US Patent:
2008017, Jul 24, 2008
Filed:
Oct 30, 2007
Appl. No.:
11/928737
Inventors:
David W. Leung - Mercer Island WA, US
Philip A. Bergman - Mountlake Terrace WA, US
Alan Lofquist - Kirkland WA, US
Gregory E. Pietz - Seattle WA, US
Christopher K. Tompkins - Bothell WA, US
David W. Waggoner - Seattle WA, US
International Classification:
C12P 21/00
C07K 1/00
C07K 16/00
C12N 15/64
US Classification:
435 697, 530399, 530351, 5303871, 4353201
Abstract:
A polyanionic polymer can improve the bioactivity and water-solubility properties of a drug to which it is joined. The inventive method provides a monodispersed preparation of a recombinantly-produced polyanionic polymer that can be easily manipulated, such as lengthened. An active moiety may be chemically or recombinantly joined to a polyanionic polymer to increase its biological half-life and/or solubility. The instant invention also provides a method for targeting the delivery of a polyanionic polymer conjugate or fusion protein to a specific cell type or tissue.

Recombinant Production Of Polyanionic Polymers And Uses Thereof

US Patent:
2002016, Nov 14, 2002
Filed:
Mar 20, 2002
Appl. No.:
10/101487
Inventors:
David Leung - Mercer Island WA, US
Philip Bergman - Mountlake Terrace WA, US
Alan Lofquist - Kirkland WA, US
Gregory Pietz - Seattle WA, US
Christopher Tompkins - Bothell WA, US
David Waggoner - Seattle WA, US
Assignee:
CELL THERAPEUTICS, INC.
International Classification:
A61K038/17
A61K038/18
A61K038/19
A61K038/20
A61K038/21
US Classification:
514/012000, 424/085100, 424/085400, 424/085200, 530/350000, 530/351000, 530/399000, 435/069500, 435/069700
Abstract:
A polyanionic polymer can improve the bioactivity and water-solubility properties of a drug to which it is joined. The inventive method provides a monodispersed preparation of a recombinantly-produced polyanionic polymer that can be easily manipulated, such as lengthened. An active moiety may be chemically or recombinantly joined to a polyanionic polymer to increase its biological half-life and/or solubility. The instant invention also provides a method for targeting the delivery of a polyanionic polymer conjugate or fusion protein to a specific cell type or tissue.

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