Gregory W Plowman, Age 6222 Seven Sister Rd, Haverhill, MA 01830

Gregory Plowman Phones & Addresses

22 Seven Sister Rd, Haverhill, MA 01830 (617) 966-3693

13 Old Jacobs Rd, Georgetown, MA 01833 (978) 352-3866

13R Old Jacobs Rd, Georgetown, MA 01833

Bennington, NH

58 Bacon St, Winchester, MA 01890 (781) 721-2576 (781) 729-4981

Danvers, MA

Woburn, MA

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Mentions for Gregory W Plowman

Publications & IP owners

Us Patents

Compounds To Fibroblast Growth Factor Receptor-3 (Fgfr3) And Methods Of Treatment

US Patent:
2015016, Jun 18, 2015
Filed:
Dec 11, 2014
Appl. No.:
14/567063
Inventors:
- INDIANAPOLIS IN, US
- WALTHAM MA, US
Hans K. ERICKSON - Waltham MA, US
Dale L. LUDWIG - Denville NJ, US
Christopher M. MOXHAM - Princeton Junction NJ, US
Gregory D. PLOWMAN - New York NY, US
Alan C. RIGBY - Glen Ridge NJ, US
Assignee:
IMCLONE LLC - INDIANAPOLIS IN
IMMUNOGEN, INC. - WALTHAM MA
International Classification:
A61K 47/48
A61K 31/395
A61K 45/06
Abstract:
The invention provides conjugates that consist of a drug moiety agent and a cell binding agent that target human fibroblast growth factor receptor 3 (FGFR3). These conjugates have therapeutic use as they are designed and tailored to target a specific cell population and deliver a powerful cytotoxin inside the cell. The conjugate of the present invention has significant advantages over other conjugates known in the art by providing a targeted tumor therapy as well as bystander activity to neighboring cells in an important oncology receptor that is only moderately expressed.

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