Career records & work history
Medicine Doctors
Hao Liu, Age 396731 Holly Heath Dr, Riverview, FL 33578
Hao Liu Phones & Addresses
6731 Holly Heath Dr, Riverview, FL 33578 (813) 528-2261
Brandon, FL
Tampa, FL
Hillsboro Bch, FL
8182 Stone View Dr, Tampa, FL 33647
Work
Company:
H. lee moffitt cancer center Mar 2013
Position:
Postdoctoral fellow
Education
School / High School:
University of York- York, PA 2005
Specialities:
Ph.D in Immunology
Skills
molecular cloning • site-directed mutagenesis • real-time PCR • NGS • mRNA differential display • Southern blot • expression of protein • purification of protein • luciferase reporter assay • Western blot • GST-pull down • co-immunoprecipitation • antibody preparation • in vitro translation • yeast two-hybrid system • conditional knockout mice models • HSC/bone marrow adoptive transfer • tumor bearing mice handling • tissue and primary cell culture • culture of tumor-infiltrating lymphocytes • transient and stable transfection • confocal microscopy • live cell imaging • immunohistochemistry • gene knockdown (shRNA and siRNA) • microarray • lentiviral transduction • multicolor flow cytometry • MACS purification • mixed lymphocyte reaction • chemotaxis assay • ELISA • Elispot • parasite preparation and infection
Mentions for Hao Liu
Hao Liu resumes & CV records
Resumes
Hao Liu
Hao Liu
Hao Liu
Hao Liu
Work:
Hao's Healing Lounge
Omd
Omd
Hao Liu
Hao Jan Max Liu
Hao Liu
Location:
United States
Hao Liu - Tampa, FL
Work:
H. Lee Moffitt Cancer Center Mar 2013 to 2000
Postdoctoral fellow H. Lee Moffitt Cancer Center - Tampa, FL 2009 to 2013
Postdoctoral Fellow School of Pharmacy, The University of Nottingham (UK) - Nottingham, NH Mar 2005 to Aug 2005
Research Associate Dept. of Biochemistry, the University of Leicester (UK) - Leicester, MA Sep 2004 to Feb 2005
Research Assistant Shanghai Genomics Inc 2001 to 2003
Research Assistant/Associate
Postdoctoral fellow H. Lee Moffitt Cancer Center - Tampa, FL 2009 to 2013
Postdoctoral Fellow School of Pharmacy, The University of Nottingham (UK) - Nottingham, NH Mar 2005 to Aug 2005
Research Associate Dept. of Biochemistry, the University of Leicester (UK) - Leicester, MA Sep 2004 to Feb 2005
Research Assistant Shanghai Genomics Inc 2001 to 2003
Research Assistant/Associate
Education:
University of York - York, PA 2005 to 2009
Ph.D in Immunology University of Leicester - Leicester 2003 to 2004
M.Sc in Molecular Genetics School of Life Sciences, Shanghai University 1997 to 2001
B.S. in Bioengineering
Ph.D in Immunology University of Leicester - Leicester 2003 to 2004
M.Sc in Molecular Genetics School of Life Sciences, Shanghai University 1997 to 2001
B.S. in Bioengineering
Skills:
molecular cloning, site-directed mutagenesis, real-time PCR, NGS, mRNA differential display, Southern blot, expression of protein, purification of protein, luciferase reporter assay, Western blot, GST-pull down, co-immunoprecipitation, antibody preparation, in vitro translation, yeast two-hybrid system, conditional knockout mice models, HSC/bone marrow adoptive transfer, tumor bearing mice handling, tissue and primary cell culture, culture of tumor-infiltrating lymphocytes, transient and stable transfection, confocal microscopy, live cell imaging, immunohistochemistry, gene knockdown (shRNA and siRNA), microarray, lentiviral transduction, multicolor flow cytometry, MACS purification, mixed lymphocyte reaction, chemotaxis assay, ELISA, Elispot, parasite preparation and infection
Publications & IP owners
Us Patents
Tumor-Infiltrating Lymphocytes For Adoptive Cell Therapy
US Patent:
2022028, Sep 8, 2022
Filed:
May 24, 2022
Appl. No.:
17/752481
Inventors:
- Tampa FL, US
Mark McLaughlin - Tampa FL, US
Hao Liu - Tampa FL, US
Mark McLaughlin - Tampa FL, US
Hao Liu - Tampa FL, US
International Classification:
C12N 5/0783
A61K 39/00
A61K 35/12
G01N 33/50
A61K 39/00
A61K 35/12
G01N 33/50
Abstract:
Disclosed are compositions and methods for ex vivo expansion of tumorinfiltrating lymphocytes for use in adoptive cell therapy (ACT). Also disclosed are compositions and method for identifying an agent for ex vivo expansion of tumorinfiltrating lymphocytes for use in ACT. Also disclosed are methods for treating cancer using tumor-infiltrating lymphocytes expanded by the disclosed methods.
Tumor-Infiltrating Lymphocytes For Adoptive Cell Therapy
US Patent:
2019017, Jun 13, 2019
Filed:
Feb 11, 2019
Appl. No.:
16/272524
Inventors:
- Tampa FL, US
Mark McLaughlin - Tampa FL, US
Hao Liu - Tampa FL, US
Mark McLaughlin - Tampa FL, US
Hao Liu - Tampa FL, US
International Classification:
C12N 5/0783
G01N 33/50
A61K 39/00
G01N 33/50
A61K 39/00
Abstract:
Disclosed are compositions and methods for ex vivo expansion of tumor-infiltrating lymphocytes for use in adoptive cell therapy (ACT). Also disclosed are compositions and method for identifying an agent for ex vivo expansion of tumor-infiltrating lymphocytes for use in ACT. Also disclosed are methods for treating cancer using tumor-infiltrating lymphocytes expanded by the disclosed methods.
Method Of Ex Vivo Enhancement Of Immune Cell Activity For Cancer Immunotherapy With A Small Molecule Ablative Compound
US Patent:
2019003, Jan 31, 2019
Filed:
Oct 2, 2018
Appl. No.:
16/149468
Inventors:
- Knoxville TN, US
- Tampa FL, US
Amod SARNAIK - Tampa FL, US
Hao LIU - Tampa FL, US
- Tampa FL, US
Amod SARNAIK - Tampa FL, US
Hao LIU - Tampa FL, US
Assignee:
Provectus Pharmatech, Inc. - Knoxville TN
H. Lee Moffitt Cancer Center and Research Institute, Inc. - Tampa FL
H. Lee Moffitt Cancer Center and Research Institute, Inc. - Tampa FL
International Classification:
A61K 35/17
A61K 38/17
A61K 39/395
A61K 38/21
A61K 39/00
A61K 31/352
C12P 21/00
C12P 21/02
A61K 35/15
C07K 16/28
A61K 38/17
A61K 39/395
A61K 38/21
A61K 39/00
A61K 31/352
C12P 21/00
C12P 21/02
A61K 35/15
C07K 16/28
Abstract:
A cancer immunotherapy method is disclosed in which “induced immune anticancer agents” are isolated after being induced in an animal host by intralesional (IL) administration of a halogenated xanthene tumor-ablative compound into a solid cancerous tumor of that host animal. A sample of the induced immune anticancer agents is removed (collected) from the tumor-bearing host, banked if desired, cultured and preferentially expanded to form an immunologically-effective enriched tumor-specific immune anticancer agent composition. That composition is reintroduced in to the host from which the predecessor induced immune anticancer agents were taken, or into another immunologically suitable host in need.
Method Of Ex Vivo Enhancement Of Immune Cell Activity For Cancer Immunotherapy With A Small Molecule Ablative Compound
US Patent:
2017017, Jun 22, 2017
Filed:
Dec 18, 2015
Appl. No.:
14/974357
Inventors:
Jamie Singer - Knoxville TN, US
Eric Wachter - Oak Ridge TN, US
Amod Sarnaik - Tampa FL, US
Shari Pilon-Thomas - Tampa FL, US
Hao Liu - Tampa FL, US
Eric Wachter - Oak Ridge TN, US
Amod Sarnaik - Tampa FL, US
Shari Pilon-Thomas - Tampa FL, US
Hao Liu - Tampa FL, US
Assignee:
PROVECTUS PHARMATECH, INC. - Knoxville TN
International Classification:
A61K 35/17
A61K 35/15
A61K 31/352
C12P 21/02
A61K 38/17
A61K 38/21
C12P 21/00
C07K 16/28
A61K 39/395
A61K 35/15
A61K 31/352
C12P 21/02
A61K 38/17
A61K 38/21
C12P 21/00
C07K 16/28
A61K 39/395
Abstract:
A cancer immunotherapy method is disclosed in which “induced immune anticancer agents” are isolated after being induced in an animal host by intralesional (IL) administration of a halogenated xanthene tumor-ablative compound into a solid cancerous tumor of that host animal. A sample of the induced immune anticancer agents is removed (collected) from the tumor-bearing host, banked if desired, cultured and preferentially expanded to form an immunologically-effective enriched tumor-specific immune anticancer agent composition. That composition is reintroduced in to the host from which the predecessor induced immune anticancer agents were taken, or into another immunologically suitable host in need.
Tumor-Infiltrating Lymphocytes For Adoptive Cell Therapy
US Patent:
2017008, Mar 23, 2017
Filed:
Mar 20, 2015
Appl. No.:
15/126436
Inventors:
- Tampa FL, US
Mark McLaughlin - Tampa FL, US
Hao Liu - Tampa FL, US
Mark McLaughlin - Tampa FL, US
Hao Liu - Tampa FL, US
International Classification:
C12N 5/0783
G01N 33/50
A61K 39/00
G01N 33/50
A61K 39/00
Abstract:
Disclosed are compositions and methods for ex vivo expansion of tumorinfiltrating lymphocytes for use in adoptive cell therapy (ACT). Also disclosed are compositions and method for identifying an agent for ex vivo expansion of tumorinfiltrating lymphocytes for use in ACT. Also disclosed are methods for treating cancer using tumor-infiltrating lymphocytes expanded by the disclosed methods.
Possible Relatives
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