Henry Marshall Fales DeceasedSilver Spring, MD

Henry Fales Phones & Addresses

Silver Spring, MD

63 Orchard Way, Potomac, MD 20854 (301) 294-8788

Bethesda, MD

3160 Gracefield Rd UNIT 2222, Silver Spring, MD 20904 (301) 572-4257

Work

Position: Protective Service Occupations

Education

Degree: Associate degree or higher

Mentions for Henry Marshall Fales

Publications & IP owners

Us Patents

Compounds With Mdr1-Inverse Activity

US Patent:
2010031, Dec 16, 2010
Filed:
Feb 10, 2009
Appl. No.:
12/867206
Inventors:
Matthew D. Hall - Washington DC, US
Michael M. Gottesman - Bethesda MD, US
Jennifer L. Hellawell - Philadelphia PA, US
Joseph A. Ludwig - Houston TX, US
Henry M. Fales - Silver Spring MD, US
Noeris K. Salam - Jersey City NJ, US
Gergely Szakács - Budapest, HU
International Classification:
A61K 39/395
A61K 31/404
A61K 31/44
A61K 31/175
A61K 31/403
A61K 31/351
A61K 31/7068
A61K 31/704
A61K 31/437
A61K 31/7048
A61K 31/337
A61K 31/506
A61K 38/12
A61P 35/00
A61P 35/02
US Classification:
4241741, 514418, 514353, 514583, 514581, 514411, 514459, 514 49, 514 34, 514285, 514 27, 514449, 51425218, 514 199
Abstract:
Disclosed herein are drug compounds that have MDR-inverse activity and thus are effective against multidrug-resistant cells. Exemplary compounds disclosed herein have the structure:Examples of the disclosed compounds have been found to have, inter alia, efficacy in directly treating multidrug resistant cells, rendering multidrug resistant cells susceptible to other chemotherapeutics and in some instances reversing multidrug resistance.

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