Inventors:
Kyoichi A. Watanabe - Rye Brook NY
Krzysztof W. Pankiewicz - Bronxville NY
Jacek Krzeminski - Bronxville NY
Barbara Nawrot - Zgierz, PL
Assignee:
Sloan-Kettering Institute for Cancer Research - New York NY
International Classification:
C07H 1916
C07H 1919
C07H 19167
C07H 19173
Abstract:
The present invention provides a compound having the structure: ##STR1## wherein R. sup. 1 is hydrogen, benzyl or a substituted benzyl group; X is hydrogen, a flouro, an amino or a substituted amino group; Y is hydrogen, a methoxy, a methylthio, a benzylthio, a methylethyl, a chloro, an amino or a substituted amino group; and Y' is an oxo or a thio group; and Z is hydrogen, a hydroxy, a methoxy, a halogen, an amino or a substituted amino group. The present invention also provides a method of synthesizing a compound having the above-identified structure as well as the intermediate compounds produced according to that method.