James R Empfield, Age 63Natick, MA
James Empfield Phones & Addresses
Natick, MA
Jacksonville, FL
10 Cider Mill Ct, Garnet Valley, PA 19060 (610) 358-9715
Boothwyn, PA
224 Rushes Dr, Bear, DE 19701 (302) 834-9519
33 Antioch Ct, New Castle, DE 19720
Philadelphia, PA
Concordville, PA
Los Angeles, CA
10 Cider Mill Rd, Garnet Valley, PA 19060
Work
Position:
Professional/Technical
Education
Degree:
Graduate or professional degree
Mentions for James R Empfield
Publications & IP owners
Us Patents
Alpha-Substituted Pyridazino Quinoline Compounds
US Patent:
6737424, May 18, 2004
Filed:
Nov 16, 1998
Appl. No.:
09/192713
Inventors:
Thomas Michael Bare - West Chester PA
James Roy Empfield - Bear DE
Janet Marie Forst - Wilmington DE
Keith John Herzog - Wilmington DE
Richard Bruce Sparks - Linwood PA
James Roy Empfield - Bear DE
Janet Marie Forst - Wilmington DE
Keith John Herzog - Wilmington DE
Richard Bruce Sparks - Linwood PA
Assignee:
Zeneca Ltd. - London
International Classification:
A61K 315025
US Classification:
514248, 544230, 544234
Abstract:
Alpha-substituted pyridazino-quinoline compounds of formula Ia useful for the treatment of strokes and neurodegenerative disorders: wherein R is selected from a variety of substituents including halogen, (C -C )alkyl and nitro; R is selected from cycloalkyl moieties of 5-7 carbon atoms and the groups R2â and R2â as defined in the specification, a dashed bond indicates a single or double bond, and R is selected from H and CO(C -C )alkyl.
Compounds For The Treatment Of Dementia Related Diseases
US Patent:
7205314, Apr 17, 2007
Filed:
Dec 18, 2002
Appl. No.:
10/499217
Inventors:
Stefan Berg - Södertälje, SE
Ratan Bhat - Södertälje, SE
James Empfield - Wilmington DE, US
Sven Hellberg - Södertälje, SE
Michael Klimas - Milwaukee WI, US
James Woods - Wilmington DE, US
Ratan Bhat - Södertälje, SE
James Empfield - Wilmington DE, US
Sven Hellberg - Södertälje, SE
Michael Klimas - Milwaukee WI, US
James Woods - Wilmington DE, US
Assignee:
AstraZeneca AB - Sodertalje
International Classification:
A61K 31/47
C07D 217/16
C07D 217/16
US Classification:
514307, 514310, 514301, 514302, 514303, 5142662, 546143, 546144, 546114, 546115, 546117, 546118, 544283
Abstract:
The present invention relates to new compounds of formula (I) wherein Y, P, R, R, R, n, m are defined as in claim , a process for their preparation and new intermediates used therein, pharmaceutical composition containing said therapeutically active compounds and to the use of said active compounds in therapy, especially in the prevention and/or treatment of dementia related disease, Alzheimer's Disease and conditions associated with glycogen synthase kinase-3.
4-Substituted Imidazoles
US Patent:
7384954, Jun 10, 2008
Filed:
Nov 15, 2004
Appl. No.:
10/579609
Inventors:
James R. Empfield - Wilmington DE, US
Eifion Phillips - Boothwyn PA, US
Scott Throner - Wilmington DE, US
Eifion Phillips - Boothwyn PA, US
Scott Throner - Wilmington DE, US
Assignee:
AstraZeneca AB - Sodertalje
International Classification:
A01N 43/42
A61K 31/44
C07D 221/02
A61K 31/44
C07D 221/02
US Classification:
514299, 546112
Abstract:
Compounds of formula I:.
Metabotropic Glutamate Receptor Isoxazole Ligands And Their Use As Potentiators—286
US Patent:
7781434, Aug 24, 2010
Filed:
Oct 8, 2009
Appl. No.:
12/575891
Inventors:
Joseph Cacciola - Wilmington DE, US
James Empfield - Wilmington DE, US
James Folmer - Wilmington DE, US
Angela M Hunter - Wilmington DE, US
Scott Throner - Wilmington DE, US
James Empfield - Wilmington DE, US
James Folmer - Wilmington DE, US
Angela M Hunter - Wilmington DE, US
Scott Throner - Wilmington DE, US
Assignee:
AstraZeneca AB - Sodertalje
International Classification:
A61K 31/5377
C07D 413/14
C07D 413/14
US Classification:
5142352, 544140
Abstract:
Compounds in accord with Formula I:.
Metabotropic Glutamate Receptor Isoxazole Ligands And Their Use As Potentiators 286
US Patent:
7790760, Sep 7, 2010
Filed:
Jun 3, 2009
Appl. No.:
12/477347
Inventors:
Joseph Cacciola - Wilmington DE, US
James Empfield - Wilmington DE, US
James Folmer - Wilmington DE, US
Angela M. Hunter - Wilmington DE, US
Scott Throner - Wilmington DE, US
James Empfield - Wilmington DE, US
James Folmer - Wilmington DE, US
Angela M. Hunter - Wilmington DE, US
Scott Throner - Wilmington DE, US
Assignee:
AstraZeneca AB - Sodertalje
International Classification:
A61K 31/422
C07D 261/18
C07D 261/18
US Classification:
514378, 548248
Abstract:
Compounds in accord with Formula I:.
Metabotropic Glutamate Receptor Oxadiazole Ligands And Their Use As Potentiators 841
US Patent:
7799792, Sep 21, 2010
Filed:
Jun 6, 2008
Appl. No.:
12/134520
Inventors:
Joshua Clayton - Oakville, CA
Ian Egle - North York, CA
James Empfield - Wilmington DE, US
James Folmer - Wilmington DE, US
Methvin Isaac - Brampton, CA
Fupeng Ma - Melrose MA, US
Abdelmalik Slassi - Mississauga, CA
Ian Egle - North York, CA
James Empfield - Wilmington DE, US
James Folmer - Wilmington DE, US
Methvin Isaac - Brampton, CA
Fupeng Ma - Melrose MA, US
Abdelmalik Slassi - Mississauga, CA
Assignee:
AstraZeneca AB - Sodertalje
International Classification:
A61K 31/496
C07D 413/04
C07D 413/14
A61K 31/4245
C07D 413/04
C07D 413/14
A61K 31/4245
US Classification:
51425403, 514364, 544367, 548131
Abstract:
Compounds of Formula I:.
Metabotropic Glutamate Receptor Isoxazole Ligands And Their Use As Potentiators
US Patent:
7888353, Feb 15, 2011
Filed:
Aug 26, 2010
Appl. No.:
12/869263
Inventors:
Joseph Cacciola - Wilmington DE, US
James Empfield - Wilmington DE, US
James Folmer - Wilmington DE, US
Angela M Hunter - Wilmington DE, US
Scott Throner - Wilmington DE, US
James Empfield - Wilmington DE, US
James Folmer - Wilmington DE, US
Angela M Hunter - Wilmington DE, US
Scott Throner - Wilmington DE, US
Assignee:
AstraZeneca AB - Sodertalje
International Classification:
A61K 31/5377
C07D 413/14
C07D 413/14
US Classification:
5142352, 544137
Abstract:
Compounds in accord with Formula I:.
Metabotropic Glutamate Receptor Isoxazole Ligands And Their Use As Potentiators—286
US Patent:
8148372, Apr 3, 2012
Filed:
Aug 20, 2010
Appl. No.:
12/860330
Inventors:
Joseph Cacciola - Wilmington DE, US
James Empfield - Wilmington DE, US
James Folmer - Wilmington DE, US
Angela M Hunter - Wilmington DE, US
Scott Throner - Wilmington DE, US
James Empfield - Wilmington DE, US
James Folmer - Wilmington DE, US
Angela M Hunter - Wilmington DE, US
Scott Throner - Wilmington DE, US
Assignee:
AstraZeneca AB - Sodertalje
International Classification:
A61K 31/5377
C07D 413/14
A61K 31/422
C07D 261/18
C07D 413/14
A61K 31/422
C07D 261/18
US Classification:
5142352, 514378, 544137, 544140, 548248
Abstract:
Compounds in accord with Formula I:.
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