Jayanta Kumar Saha, Age 69901 Savoy Way, Apex, NC 27502

Jayanta Saha Phones & Addresses

901 Savoy Way, Apex, NC 27502 (919) 303-0194

Durham, NC

106 Hollowoak Ct, Cary, NC 27513 (919) 481-0478

Cambridge, MA

Brighton, MA

Work

Position: Professional/Technical

Education

Degree: Graduate or professional degree

Mentions for Jayanta Kumar Saha

Jayanta Saha resumes & CV records

Resumes

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Jayanta Saha

Location:
United States
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Jayanta Saha

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Jayanta Saha

Publications & IP owners

Us Patents

Compositions And Methods For Cancer Treatment

US Patent:
2010022, Sep 9, 2010
Filed:
May 19, 2010
Appl. No.:
12/782774
Inventors:
Jayanta Saha - Apex NC, US
International Classification:
A61K 31/704
C07H 15/252
C07F 9/535
A61K 31/675
C07H 19/06
A61K 31/7068
A61P 35/00
US Classification:
514 34, 536 64, 546 23, 514 81, 544243, 514 86, 536 268, 514 49
Abstract:
A novel composition of a phosphonoformic acid partial ester chemically linked to an anticancer compound of the general formula:wherein Ris selected from the group consisting of methyl, alkyl, cholesteryl, aryl and aralkyl, Ris selected from the group consisting of hydrogen, methyl, alkyl, and a water-soluble cation, Y is selected from the group consisting of oxygen, sulfur, carbon and nitrogen, and Ris a cytotoxic agent. Methods for making and administering these compositions for treatment of cancer are also disclosed.

Compositions And Methods For Cancer Treatment

US Patent:
2008029, Nov 27, 2008
Filed:
Dec 19, 2007
Appl. No.:
11/960031
Inventors:
Jayanta Saha - Apex NC, US
Assignee:
Saha Pharmaceuticals, Inc. - Research Triangle Park NC
International Classification:
A61K 31/675
A61P 35/00
C07H 15/252
C07F 9/6561
A61K 31/7068
A61P 35/02
C07F 9/6558
C07H 19/10
A61K 31/704
US Classification:
514 34, 536 64, 546 23, 544243, 536 268, 514 81, 514 86, 514 49
Abstract:
This invention provides methods, novel formulations and kits to reduce the toxicity of anticancer drugs. Disclosed are therapeutics and treatment methods employing anticancer drags that exhibit a known toxicity, including, for example, adriamycin, campthothecin, and the like, chemically linked to a phosphonoformic acid partial ester resulting in a novel formulation that significantly decreases drug-related toxicity, enhances synergy with other chemotherapeutic drugs and provides increased efficacy against drug-resistant cancers.

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