Inventors:
David Rank - Palo Alto CA, US
Jonas Korlach - Menlo Park CA, US
Yue Xu - Fremont CA, US
Stephen Turner - Menlo Park CA, US
Jeffrey Wegener - Cupertino CA, US
Daniel Roitman - Menlo Park CA, US
John Lyle - Redwood Shores CA, US
Assignee:
Pacific Biosciences of California, Inc. - Menlo Park CA
International Classification:
C12Q 1/68
US Classification:
514 44, 424 111, 424 851, 424 931, 424 941, 4241301, 435 5, 435 6, 435 911, 4353201, 435325, 436536, 436518, 530300, 530333, 536 231
Abstract:
Methods of producing substrates having selected active chemical regions by employing elements of the substrates in assisting the localization of active chemical groups in desired regions of the substrate. The methods may include optical, chemical and/or mechanical processes for the deposition, removal, activation and/or deactivation of chemical groups in selected regions of the substrate to provide selective active regions of the substrate.