Jian Liao resumes & CV records
Resumes
Jian Ying Liao, Age 61256 Alta Loma Ave, Daly City, CA 94015
Jian Liao Phones & Addresses
256 Alta Loma Ave, Daly City, CA 94015 (650) 997-0485
Monterey Park, CA
Danville, CA
6683 Whistling Swan Way, Las Vegas, NV 89118
San Francisco, CA
San Mateo, CA
Mentions for Jian Ying Liao
Publications & IP owners
Us Patents
Difference Detection Methods Using Isoelectric Focusing Chips
US Patent:
2008022, Sep 11, 2008
Filed:
Nov 27, 2007
Appl. No.:
11/998166
Inventors:
Jian Liao - Union City CA, US
International Classification:
G01N 33/53
US Classification:
435 71, 20440301
Abstract:
The present invention provides an isoelectric focusing difference detection method, as well as an isoelectric focusing chip and device. The method entails labeling proteins in the first sample with a first label, and labeling proteins in the second sample with a second, different label, wherein each label has ionic and pH characteristics whereby, upon isoelectric focusing, relative migration of a protein labeled with the first label is substantially the same as relative migration of the same protein labeled with the second label. The samples are subjected to isoelectric focusing to produce a pattern of separated proteins from both samples, which is then detected to compare the protein composition of the samples. The method can be carried with a novel isoelectric focusing chip including a substrate comprising a channel for carrying out isolectric focusing. The substrate includes a non-fluorescent or low-fluorescence material in a detection region of the channel, facilitating direct detection of the pattern of separated proteins, which makes the chip particularly useful for clinical applications, including use disease diagnosis and monitoring.
Possible Relatives
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