John M Lipari, Age 71Franksville, WI

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Mount Pleasant, WI

Milwaukee, WI

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Publications & IP owners

Us Patents

Pharmaceutical Composition

US Patent:
6458818, Oct 1, 2002
Filed:
Jul 2, 1999
Appl. No.:
09/347077
Inventors:
John Lipari - Racine WI
Soumojeet Ghosh - Lindenhurst IL
Rong Gao - Park City IL
Dilip Kaul - Gurnee IL
Assignee:
Abbott Laboratories - Abbott Park IL
International Classification:
A61K 31425
US Classification:
514365
Abstract:
A liquid pharmaceutical composition providing improved oral bioavailability is disclosed for compounds which are inhibitors of HIV protease. In particular, the composition comprises a solution in a pharmaceutically acceptable organic solvent of (a) the HIV protease inhibitor and, optionally, (b) a surfactant. The composition can optionally be encapsulated in either hard gelatin capsules or soft elastic capsules (SEC).

Pharmaceutical Composition

US Patent:
6521651, Feb 18, 2003
Filed:
Sep 10, 1999
Appl. No.:
09/393872
Inventors:
John Lipari - Racine WI
Soumojeet Ghosh - Lindenhurst IL
Rong Gao - Park City IL
Dilip Kaul - Gurnee IL
Assignee:
Abbott Laboratories - Abbott Park IL
International Classification:
A61K 31425
US Classification:
514365
Abstract:
A liquid pharmaceutical composition providing improved oral bioavailability is disclosed for compounds which are inhibitors of HIV protease. In particular, the composition comprises a solution in a pharmaceutically acceptable organic solvent of (a) the HIV protease inhibitor and, optionally, (b) a surfactant. The composition can optionally be encapsulated in either hard gelatin capsules or soft elastic capsules (SEC).

Formulations Comprising Lipid-Regulating Agents

US Patent:
6814977, Nov 9, 2004
Filed:
Dec 18, 1998
Appl. No.:
09/216247
Inventors:
John M. Lipari - Racine WI
Dawn M. Raymond - Solana Beach CA
Tom Reiland - Gages Lake IL
Assignee:
Abbott Laboratories - Abbott Park IL
International Classification:
A61K 3119
US Classification:
424451, 514557, 514576
Abstract:
The present invention is directed to a formulation comprising a lipid-regulating agent dissolved in at least one medium chain glycerol ester of a fatty acid as the primary solvent medium for said agent. One or more emulsifiers may be added to the formulation.

Formulations Comprising Lipid-Regulating Agents

US Patent:
6838091, Jan 4, 2005
Filed:
Dec 18, 1998
Appl. No.:
09/215831
Inventors:
John M. Lipari - Racine WI, US
Dawn M. Raymond - Solana Beach CA, US
Tom Reiland - Gages Lake IL, US
Yeshwant D. Sanzgiri - Gurnee IL, US
Assignee:
Abbott Laboratories - Abbott Park IL
International Classification:
A61K 948
A61K 31215
A61K 3119
US Classification:
424451, 424400, 424455, 424456, 514506, 514555
Abstract:
The present invention is directed to a formulation comprising a lipid-regulating agent dissolved in at least one monoglyceride as the primary solvent medium for said agent. One or more emulsifiers may be added to the formulation.

Formulations Comprising Lipid-Regulating Agents

US Patent:
7014864, Mar 21, 2006
Filed:
Dec 18, 1998
Appl. No.:
09/216242
Inventors:
John M. Lipari - Racine WI, US
Dawn M. Raymond - Solana Beach CA, US
Tom Reiland - Gages Lake IL, US
Assignee:
Abbott Laboratories - Abbott Park IL
International Classification:
A61K 31/19
A61K 9/48
A61K 31/215
US Classification:
424451, 424400, 424455, 424456, 514506, 514555, 514576
Abstract:
The present invention is directed to a formulation comprising a lipid-regulating agent dissolved in at least one structured lipid as the primary solvent medium for said agent. One or more emulsifiers may be added to the formulation.

Pharmaceutical Composition

US Patent:
2003003, Feb 13, 2003
Filed:
May 24, 2002
Appl. No.:
10/154727
Inventors:
John Lipari - Racine WI, US
Soumojeet Ghosh - Lindenhurst IL, US
Rong Gao - Park City IL, US
Dilip Kaul - Gurnee IL, US
International Classification:
A61K031/551
A61K031/20
US Classification:
514/050000, 514/220000, 514/558000
Abstract:
A liquid pharmaceutical composition providing improved oral bioavailability is disclosed for compounds which are inhibitors of HIV protease. In particular, the composition comprises a solution in a pharmaceutically acceptable organic solvent of (a) the HIV protease inhibitor and, optionally, (b) a surfactant. The composition can optionally be encapsulated in either hard gelatin capsules or soft elastic capsules (SEC).

Alpha-Hydroxy Acid Ester Drug Delivery Compositions And Methods Of Use

US Patent:
2004019, Sep 30, 2004
Filed:
Mar 31, 2003
Appl. No.:
10/403071
Inventors:
John Lipari - Racine WI, US
Michelle Long - Libertyville IL, US
International Classification:
A61K009/48
A61K031/19
A61K007/06
US Classification:
424/074000, 514/557000
Abstract:
Delivery compositions having an alpha-hydroxy acid ester and an acylglycerol as part of a carrier composition for pharmaceutical drug actives or prodrugs are described. These formulations display unique properties aiding in the delivery of the drug to a subject.

Novel Formulations Comprising Lipid-Regulating Agents

US Patent:
2005011, May 26, 2005
Filed:
Nov 19, 2004
Appl. No.:
10/993239
Inventors:
John Lipari - Racine WI, US
Dawn Raymond - Solana Beach CA, US
Tom Reiland - Gages Lake IL, US
Yeshwant Sanzgiri - Gurnee IL, US
International Classification:
A61K009/48
A61K035/78
A61K031/192
US Classification:
424451000, 514571000, 424731000
Abstract:
The present invention is directed to a formulation comprising a lipid-regulating agent dissolved in at least one monoglyceride as the primary solvent medium for said agent. One or more emulsifiers may be added to the formulation.

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