Jonathan Ryan Black, Age 3810 Matthew Dr, Romansville, PA 19320

4430999, Feb 14, 1984

Nov 10, 1981

6/320309

Carl T. Brighton - Malvern PA
Jonathan Black - King of Prussia PA
Joyce K. Eyerly - White Bear Lake MN

Trustees of the University of Pennsylvania
Zimmer, Inc.

A61N 118

128419F

A cathode assembly for use in conjunction with an internal fracture fixation device for the purpose of stimulating osteogenesis (bone growth) within a fracture site. The assembly is comprised of a carrier made from an implantable non-conductive material containing a cathode with a conductive cable leading from the cathode to the patient's electrical bone growth stimulating apparatus. The carrier is mountable on the fixation device for maintenance at the desired location. In a preferred embodiment, a sleeve carrier contains a plurality of ports which allow the current generated by the stimulating device to flow through the cable to the cathode where it is evenly distributed through the ports to the bone tissue. The sleeve can be slipped onto a fracture fixation device, such as a compression hip screw, and is located on the device such that the sleeve containing the cathode lies across the fracture site.

4519394, May 28, 1985

Mar 7, 1983

6/472567

Jonathan Black - King of Prussia PA
Thomas J. Baranowski - Philadelphia PA

Trustees of the University of Pennsylvania - Philadelphia PA

A61N 120

128419F

Disclosed is a method and apparatus for maintaining the potential between a cathode and a reference electrode substantially constant during electrically-induced osteogenesis. Two separate embodiments of electronic circuits are provided which will generate a D. C. current to flow between a cathode and anode while maintaining the potential between the cathode and the reference electrode substantially constant within the range of 0. 1 to 1. 26 Volts and preferably within the range of 1. 0 to 1. 26 Volts. Improvement in the amount of new bone grown over prior art bone growth stimulators is on the order of 200 to 300 percent. The electronic circuits provide the substantially constant cathodic potential over a wide range of load impedances between the anode and cathode. The disclosure is applicable not only to improving osteogenesis in bone fracture sites, but also to applications in which it is desirable to provide bone accretion for any reason.

4549547, Oct 29, 1985

Jul 27, 1982

6/402316

Carl T. Brighton - Malvern PA
Jonathan Black - King of Prussia PA
William Redka - Vineland NJ

Trustees of the University of Pennsylvania - Philadelphia PA

A61N 108

128419F

Disclosed is an implantable bone growth stimulator which needs no internal battery or large buffer capacitor. A receiving coil in a preferred embodiment, a ferrite core coil, receives RF energy from a transmitter external to the patient. The received RF energy is voltage doubled and rectified and provided to a constant current generator which in turn supplies a constant amount of current between implanted cathodes and an implanted anode. In preferred embodiments, the receiving coil, power supply, and cathodes are one unit which is located in place on an internal fixation device attached to the bones near the fracture site. In another embodiment, only the cathodes are located in the vicinity of the fracture site and the receiver coil voltage multiplier circuit and constant current source are located remote from the fracture site. Additionally, the internal fixation device in a preferred embodiment may have a plastic insert therein having one or more holes therethrough for the insertion of cathodes into the vicinity of the fracture site. While a preferred embodiment utilizes the completely implanted bone growth stimulator, the plate is effectively utilized with an external bone growth stimulator power supply and percutaneous cathodes inserted through positioning holes in the plastic insert of the fixation device.

5676700, Oct 14, 1997

Feb 6, 1996

8/595932

Jonathan Black - King of Prussia PA
Michael T. Manley - Franklin Lakes NJ
Paul Serekian - Mahwah NJ

Osteonics Corp. - Allendale NJ

A61F 228

623 16

Structural elements of biocompatible material are interlocked with one another in an array to repair, augment or replace natural bone, the structural elements each including a hub having a center, and a plurality of posts projecting from the hub and spaced from one another to establish inter-post spaces between adjacent posts, each post having a root at the hub, an opposite tip, a length, and a transverse cross-sectional configuration, the number of posts and the relative length, cross-sectional configuration, and location of adjacent posts in each structural element being such that the inter-post spaces of one structural element will receive the posts of adjacent structural elements in the array to promote interlocking of adjacent structural elements in a relatively tightly meshed relationship for resisting shear stress in essentially all directions within the array.

4506674, Mar 26, 1985

Dec 22, 1983

6/564215

Carl T. Brighton - Malvern PA
Jonathan Black - King of Prussia PA

Trustees of the University of Pennsylvania - Philadelphia PA

A61N 118

128419F

Disclosed is an improved bone-piercing cathode for providing electrical stimulation of osteogenesis at a plurality of locations. A conventional bone-piercing cathode is modified by adding a number of "ports" extending through the insulative covering to expose the cathode permitting a flow of osteogenesis stimulating current therethrough. In a preferred embodiment, seven ports are spaced three on one side and four on the other of a conventional bone-piercing cathode which is inserted into the fracture site. Sufficient current is supplied to the cathode in order to insure that each port as well as the insulation-bare wire junction can supply 20 microamperes of osteogenesis stimulating current into the body tissues. This permits bone growth stimulation adjacent a plurality of sites on the cathode.