Jonathan L Ditta, Age 49New Braunfels, TX

Jonathan Ditta Phones & Addresses

New Braunfels, TX

San Antonio, TX

Huntsville, TX

101 Buckingham St, Meriden, CT 06451 (203) 440-0049

211 Pomeroy Ave APT 2417, Meriden, CT 06450 (203) 440-0049

100 Cold Spring Rd, Rocky Hill, CT 06067 (860) 436-2799

Middletown, CT

Malden, MA

Wethersfield, CT

College Station, TX

Durham, NC

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Us Patents

Cyclopropylindole Derivatives As Selective Serotonin Reuptake Inhibitors

US Patent:
6777437, Aug 17, 2004
Filed:
Mar 5, 2002
Appl. No.:
10/091232
Inventors:
Ronald J. Mattson - Meriden CT
Derek John Denhart - Wallingford CT
Jeffrey A. Deskus - Marlborough CT
Jonathan L. Ditta - Middletown CT
Lawrence R. Marcin - Bethany CT
James R. Epperson - Cromwell CT
John D. Catt - Newburgh IN
Dalton King - Hamden CT
Mendi A. Higgins - Middletown CT
Assignee:
Bristol-Myers Squibb Company - Princeton NJ
International Classification:
A61K 31405
US Classification:
514415, 548451
Abstract:
The present invention relates to compounds of Formula (I) and pharmaceutically acceptable salts or solvates thereof and pharmaceutically acceptable formulations comprising said compounds useful for the treatment of depression, anxiety disorders, premature ejaculation, chronic pain, obsessive-compulsive disorder, feeding disorders, premenstrual dysphoric disorder, panic disorders and psychotic disorders including bipolar disorder and schizophrenia.

Tetrahydroisoquinoline Derivatives As Melatonin Mt2 Antagonists

US Patent:
6908931, Jun 21, 2005
Filed:
Mar 29, 2004
Appl. No.:
10/812245
Inventors:
Gene M. Dubowchik - Middlefield CT, US
Jonathan L. Ditta - Middletown CT, US
Stephen R. Bertenshaw - Cheshire CT, US
Assignee:
Bristol-Myers Squibb Company - Princeton NJ
International Classification:
C07D217/00
A61K031/47
US Classification:
514307, 546146
Abstract:
The invention encompasses a series of tetrahydroisoquinolines of formula I which are antagonists of the human melatonin MTreceptor and are useful as chronobiotic and sleep agents.

Compounds For The Treatment Of Premature Ejaculation

US Patent:
7105516, Sep 12, 2006
Filed:
Sep 15, 2003
Appl. No.:
10/662493
Inventors:
Derek John Denhart - Durham CT, US
Jonathan L. Ditta - Middletown CT, US
Dalton King - Hamden CT, US
John E. Macor - Guilford CT, US
Lawrence R. Marcin - Bethany CT, US
Ronald J. Mattson - Meriden CT, US
Zhaoxing Meng - Middletown CT, US
Assignee:
Bristol-Myers Squibb Company - Princeton NJ
International Classification:
A61K 31/535
A61K 31/445
A61K 31/40
C07D 413/06
C07D 209/04
US Classification:
5142352, 514323, 514414, 544143, 546201, 548455, 548465
Abstract:
The present invention relates to compounds of Formula (I) and pharmaceutically acceptable salts or solvates thereof and pharmaceutically acceptable formulations comprising said compounds.

Nk-1 And Serotonin Transporter Inhibitors

US Patent:
8383821, Feb 26, 2013
Filed:
Nov 13, 2009
Appl. No.:
12/618025
Inventors:
Andrew P. Degnan - Rocky Hill CT, US
Kevin W. Gillman - Madison CT, US
Derek J. Denhart - Durham CT, US
Jonathan L. Ditta - Meriden CT, US
Ramkumar Rajamani - Middletown CT, US
Ying Han - Cheshire CT, US
George O. Tora - Langhorne PA, US
Assignee:
Bristol-Meyers Squibb Company - Princeton NJ
International Classification:
A61K 31/4523
C07D 403/14
US Classification:
546194, 546207, 546208, 546211, 546209, 546213, 546214, 514318, 514323, 514326
Abstract:
The invention encompasses compounds of Formula I, including pharmaceutically acceptable salts, their pharmaceutical compositions, and their use in treating disorders associated with an excess or imbalance of tachykinins or serotonin or both.

Nk-1 And Serotonin Transporter Inhibitors

US Patent:
2007024, Oct 25, 2007
Filed:
Apr 13, 2007
Appl. No.:
11/734809
Inventors:
Andrew Degnan - Rocky Hill CT, US
Kevin Gillman - Madison CT, US
Derek Denhart - Durham CT, US
Jonathan Ditta - Middletown CT, US
Ramkumar Rajamani - Middletown CT, US
Ying Han - Cheshire CT, US
George Tora - Meriden CT, US
International Classification:
A61K 31/5377
A61K 31/53
A61K 31/497
A61K 31/496
A61K 31/513
A61K 31/501
A61K 31/4545
A61K 31/454
C07D 413/02
C07D 403/02
C07D 401/02
US Classification:
514235500, 544129000, 544360000, 544333000, 544405000, 544238000, 544209000, 546148000, 546176000, 546208000, 546209000, 546210000, 546184000, 544310000, 514241000, 514252030, 514253010, 514269000, 514255050, 514318000, 514326000, 514317000, 514314000, 514307000
Abstract:
The invention encompasses compounds of Formula I, including pharmaceutically acceptable salts, their pharmaceutical compositions, and their use in treating disorders associated with an excess or imbalance of tachykinins or serotonin or both.

Aryl Lactam Kinase Inhibitors

US Patent:
2014003, Feb 6, 2014
Filed:
Jul 19, 2013
Appl. No.:
13/946344
Inventors:
Senliang Pan - Woodbridge CT, US
Ramkumar Rajamani - Woodbridge CT, US
Susheel Jethanand Nara - Bangalore, IN
Maheswaran Sivasamban Karatholuvhu - Chennai, IN
Tarun Kumar Maishal - Bangalore, IN
Jonathan L. Ditta - Meriden CT, US
Carolyn Diane Dzierba - Middletown CT, US
Joanne J. Bronson - Durham CT, US
John E. Macor - Guilford CT, US
International Classification:
C07D 471/04
US Classification:
514292, 546110
Abstract:
The present disclosure is generally directed to compounds which can inhibit AAK1 (adaptor associated kinase 1), compositions comprising such compounds, and methods for inhibiting AAK1.

Neurotrophic Diamide And Carbamate Agents

US Patent:
6228872, May 8, 2001
Filed:
Nov 8, 1999
Appl. No.:
9/435529
Inventors:
Gene M. Dubowchik - Middlefield CT
Jonathan L. Ditta - Middletown CT
David P. Provencal - Middletown CT
Derek J. Denhart - Wallingford CT
Assignee:
Bristol-Myers Squibb Company - Princeton NJ
International Classification:
A61K 31445
A61K 3140
C07D21118
C07D21130
US Classification:
514343
Abstract:
The present invention relates to the design, synthesis, and the peptidyl-prolyl isomerase (PPIase or rotamase) inhibitory activity of novel pyrrolidinemethyl diamide and carbamate compounds that are neurotrophic agents (i. e. compounds capable of stimulating growth or proliferation of nervous tissue) and that bind to immunophilins such as FKBP12 and inhibit their rotamase activity. This invention also relates to pharmaceutical compositions comprising these compounds.

Biaryl Kinase Inhibitors

US Patent:
2019004, Feb 7, 2019
Filed:
Sep 29, 2016
Appl. No.:
15/763281
Inventors:
- Princeton NJ, US
Ling CHEN - Doylestown PA, US
Jonathan L. DITTA - Meriden CT, US
Carolyn Diane DZIERBA - Middletown CT, US
Prasada Rao JALAGAM - Bangalore, IN
Guanglin LUO - Madison CT, US
John E. MACOR - Washington Crossing PA, US
Tarun Kumar MAISHAL - Bangalore, IN
Susheel Jethanand Nara - Chembur, Mumbai, IN
Ramkumar RAJAMANI - Acton MA, US
Ramesh Kumar SISTLA - Bangalore, IN
Soodamani THANGAVEL - Hosur, IN
International Classification:
C07D 513/04
A61P 25/16
A61P 25/18
A61P 25/28
Abstract:
The present disclosure is directed to biaryl compounds of formula (I) which can inhibit AAK1 (adaptor associated kinase 1), compositions comprising such compounds and their use for treating e.g. pain, Alzheimer's disease, Parkinson's disease and schizophrenia.

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