Jonathan G Lebowitz, Age 52570 Guerrero St UNIT 1, San Francisco, CA 94110

Jonathan Lebowitz Phones & Addresses

129 Precita Ave, San Francisco, CA 94110

3475 16Th St, San Francisco, CA 94114 (415) 355-1977

609 Alamo Ct, Mountain View, CA 94043 (650) 967-1598

Los Gatos, CA

Malibu, CA

Social networks

Jonathan G Lebowitz

Linkedin

Work

Company: City of sunnyvale Position: Teacher at city of sunnyvale

Industries

Government Administration

Mentions for Jonathan G Lebowitz

Career records & work history

Medicine Doctors

Jonathan L. Lebowitz

Specialties:
Plastic Surgery, Cosmetic Surgery
Work:
Jonathan L Lebowitz MD
29 Grn St, Huntington, NY 11743
(631) 424-0101 (phone) (631) 424-0165 (fax)
Education:
Medical School
Case Western Reserve University School of Medicine
Graduated: 1982
Procedures:
Breast Reduction, Hallux Valgus Repair, Pilonidal Cyst Excision, Skull/Facial Bone Fractures and Dislocations
Conditions:
Breast Disorders, Cleft Palate and Cleft Lip, Melanoma, Skin Cancer
Languages:
English, Spanish
Description:
Dr. Lebowitz graduated from the Case Western Reserve University School of Medicine in 1982. He works in Huntington, NY and specializes in Plastic Surgery and Cosmetic Surgery. Dr. Lebowitz is affiliated with Huntington Hospital.

Jonathan J. Lebowitz

Specialties:
Nephrology
Work:
Rutgers Robert Wood Johnson Medical School Nephrology
1 Robert Wood Johnson Pl, New Brunswick, NJ 08901
(732) 235-4453 (phone) (732) 235-7919 (fax)
Education:
Medical School
SUNY Downstate Medical Center College of Medicine
Graduated: 1995
Procedures:
Dialysis Procedures
Conditions:
Acute Renal Failure, Chronic Renal Disease, Kidney Cancer, Nephrotic Syndrome
Languages:
English, Spanish
Description:
Dr. Lebowitz graduated from the SUNY Downstate Medical Center College of Medicine in 1995. He works in New Brunswick, NJ and specializes in Nephrology. Dr. Lebowitz is affiliated with Robert Wood Johnson University Hospital.

Jonathan A. Lebowitz

Specialties:
Diagnostic Radiology
Work:
Princeton Radiology Associates
9 Ctr Dr STE 115, Monroe Township, NJ 08831
(732) 821-5563 (phone) (732) 821-6675 (fax)
Site
Princeton Radiology Associates
419 N Harrison St STE G1, Princeton, NJ 08540
(609) 921-3345 (phone) (609) 683-8847 (fax)
Site
Associated Radiologists PAHillsborough Radiology Associates
375 Us Hwy 206, Hillsborough, NJ 08844
(908) 874-7600 (phone) (908) 874-7052 (fax)
Site
Princeton Radiology Associates
300A Princeton Hightstown Rd STE 101, Hightstown, NJ 08520
(609) 921-3345 (phone) (609) 683-8847 (fax)
Site
Education:
Medical School
UMDNJ Robert Wood Johnson Medical School
Graduated: 1991
Languages:
English
Description:
Dr. Lebowitz graduated from the UMDNJ Robert Wood Johnson Medical School in 1991. He works in Princeton, NJ and 3 other locations and specializes in Diagnostic Radiology. Dr. Lebowitz is affiliated with Robert Wood Johnson University Hospital Somerset and University Medical Center Of Princeton At Plainsboro.
Jonathan Lebowitz Photo 1

Jonathan Louis Lebowitz

Specialties:
Plastic Surgery
Plastic and Reconstructive Surgery
Surgery of the Hand
Education:
Case Western Reserve University(1982)
Cleveland Clinic Foundation (1990) *Plastic Surgery
Umdnj-Univ Hosp (1986) *Surgery
UMDNJ Robert Wood Johnson (1986) *Surgery
Cleveland Clinic Fndn (1990) *Plastic Surgery
Umdnj-Univ Hosp (1987) *Surgery
UMDNJ Robert Wood Johnson (1987) *Surgery

License Records

Jonathan Joseph Lebowitz

Licenses:
License #: MT036544T - Expired
Category: Medicine
Type: Graduate Medical Trainee

Jonathan Lebowitz resumes & CV records

Resumes

Jonathan Lebowitz Photo 14

Teacher At City Of Sunnyvale

Location:
San Francisco, CA
Industry:
Government Administration
Work:
City of Sunnyvale
Teacher at City of Sunnyvale

Publications & IP owners

Us Patents

Targeted Therapeutic Proteins

US Patent:
8492338, Jul 23, 2013
Filed:
May 25, 2012
Appl. No.:
13/481244
Inventors:
Jonathan LeBowitz - Novato CA, US
Stephen M. Beverley - Clayton MO, US
William S. Sly - St. Louis MO, US
Assignee:
Biomarin Pharmaceutical Inc. - Novato CA
International Classification:
A61K 38/00
A61K 38/30
A61K 38/43
A61K 38/46
US Classification:
514 85, 424 941, 530399
Abstract:
Targeted therapeutics that localize to a specific subcellular compartment such as the lysosome are provided. The targeted therapeutics include a therapeutic agent and a targeting moiety that binds a receptor on an exterior surface of the cell, permitting proper subcellular localization of the targeted therapeutic upon internalization of the receptor. Nucleic acids, cells, and methods relating to the practice of the invention are also provided.

Lysosomal Targeting Peptides And Uses Thereof

US Patent:
8563691, Oct 22, 2013
Filed:
Feb 17, 2012
Appl. No.:
13/399844
Inventors:
Jonathan LeBowitz - Novato CA, US
John Maga - Whitefish Bay WI, US
Assignee:
Biomarin Pharmaceutical, Inc. - Novato CA
International Classification:
C07K 1/00
A61K 38/00
US Classification:
530350, 514 175
Abstract:
The present invention provides further improved compositions and methods for efficient lysosomal targeting based on the GILT technology. Among other things, the present invention provides methods and compositions for targeting lysosomal enzymes to lysosomes using furin-resistant lysosomal targeting peptides. The present invention also provides methods and compositions for targeting lysosomal enzymes to lysosomes using a lysosomal targeting peptide that has reduced or diminished binding affinity for the insulin receptor.

Formulations For Lysosomal Enzymes

US Patent:
2012014, Jun 14, 2012
Filed:
Jun 17, 2010
Appl. No.:
13/378745
Inventors:
Jonathan LeBowitz - Novato CA, US
Byeong Chang - Sherman Oaks CA, US
Assignee:
BIOMARIN PHARMACEUTICAL INC. - Novato CA
International Classification:
A61K 38/47
A61P 43/00
US Classification:
424 943
Abstract:
The present invention provides improved formulations for lysosomal enzymes useful for enzyme replacement therapy. Among other things, the present invention provides formulations that preserve or enhance the stability and/or efficacy of a lysosomal enzyme such as acid alpha-glucosidase.

Targeted Therapeutic Proteins

US Patent:
2014005, Feb 27, 2014
Filed:
Jun 18, 2013
Appl. No.:
13/920761
Inventors:
Jonathan LeBowitz - Novato CA, US
Stephen M. Beverley - Clayton MO, US
Assignee:
BIOMARIN PHARMACEUTICAL - Novato CA
International Classification:
A61K 47/48
US Classification:
424 943, 435188
Abstract:
Targeted therapeutics that localize to a specific subcellular compartment such as the lysosome are provided. The targeted therapeutics include a therapeutic agent and a targeting moiety that binds a receptor on an exterior surface of the cell, permitting proper subcellular localization of the targeted therapeutic upon internalization of the receptor. Nucleic acids, cells, and methods relating to the practice of the invention are also provided.

Hydrophobic Peptide Salts For Extended Release Compositions

US Patent:
2022028, Sep 8, 2022
Filed:
Aug 12, 2020
Appl. No.:
17/634034
Inventors:
- Novato CA, US
Sunil Kumar Battu - Novato CA, US
Joshua Laber - Novato CA, US
Karol Estrada - Navato CA, US
Jonathan LeBowitz - Novato CA, US
Joyce Chou - Novato CA, US
International Classification:
A61K 47/52
A61K 47/54
A61K 9/00
A61K 9/14
A61P 19/00
Abstract:
The present disclosure, relates, in general, to hydrophobic salts of hydrophilic peptides that form low solubility materials in aqueous solutions and are capable of extended or sustained release of the peptide component when administered to a subject. Hydrophobic salts of C-type natriuretic peptides and uses thereof are also disclosed.

Targeted Therapeutic Lysosomal Enzyme Fusion Proteins And Uses Thereof

US Patent:
2019022, Jul 25, 2019
Filed:
Apr 8, 2019
Appl. No.:
16/378163
Inventors:
- Novato CA, US
Teresa Margaret Christianson - Novato CA, US
Melita Dvorak-Ewell - Berkeley CA, US
Daniel J. Wendt - Novato CA, US
Shinong Long - Novato CA, US
Jonathan LeBowitz - Novato CA, US
Daniel Solomon Gold - Novato CA, US
International Classification:
C07K 14/65
C12N 9/24
Abstract:
The present invention relates in general to therapeutic fusion proteins useful to treat lysosomal storage diseases and methods for treating such diseases. Exemplary therapeutic fusion proteins comprise a lysosomal enzyme, a lysosomal targeting moiety, e.g., an IGF-II peptide, and a spacer peptide. Also provided are compositions and methods for treating Mucopolysaccharidosis Type IIIB (Sanfilippo B Syndrome), comprising a targeted therapeutic fusion protein comprising alpha-N-acetylglucosaminidase (Naglu), a lysosomal targeting moiety, e.g., an IGF-II peptide, and a spacer peptide.

Targeted Therapeutic Lysosomal Enzyme Fusion Proteins And Uses Thereof

US Patent:
2017035, Dec 14, 2017
Filed:
Aug 28, 2017
Appl. No.:
15/688438
Inventors:
- Novato CA, US
TERESA MARGARET CHRISTIANSON - NOVATO CA, US
MELITA DVORAK-EWELL - NOVATO CA, US
DANIEL J. WENDT - NOVATO CA, US
SHINONG LONG - NOVATO CA, US
JONATHAN LeBOWITZ - NOVATO CA, US
DANIEL SOLOMON GOLD - NOVATO CA, US
Assignee:
BIOMARIN PHARMACEUTICAL INC. - NOVATO CA
International Classification:
C07K 14/65
C12N 9/24
A61K 38/00
A61K 38/47
Abstract:
The present invention relates in general to therapeutic fusion proteins useful to treat lysosomal storage diseases and methods for treating such diseases. Exemplary therapeutic fusion proteins comprise a lysosomal enzyme, a lysosomal targeting moiety, e.g., an IGF-II peptide, and a spacer peptide. Also provided are compositions and methods for treating Mucopolysaccharidosis Type IIIB (Sanfilippo B Syndrome), comprising a targeted therapeutic fusion protein comprising alpha-N-acetylglucosaminidase (Naglu), a lysosomal targeting moiety, e.g., an IGF-II peptide, and a spacer peptide.

Targeted Therapeutic Lysosomal Enzyme Fusion Proteins And Uses Thereof

US Patent:
2016003, Feb 11, 2016
Filed:
Oct 14, 2015
Appl. No.:
14/883211
Inventors:
- Novato CA, US
Teresa Margaret Christianson - Novato CA, US
Melita Dvorak-Ewell - Berkeley CA, US
Daniel J. Wendt - Novate CA, US
Shinong Long - Novato CA, US
Jonathan LeBowitz - Novato CA, US
Daniel Solomon Gold - Novato CA, US
International Classification:
C07K 14/65
C12N 9/24
Abstract:
The present invention relates in general to therapeutic fusion proteins useful to treat lysosomal storage diseases and methods for treating such diseases. Exemplary therapeutic fusion proteins comprise a lysosomal enzyme, a lysosomal targeting moiety, e.g., an IGF-II peptide, and a spacer peptide. Also provided are compositions and methods for treating Mucopolysaccharidosis Type IIIB (Sanfilippo B Syndrome), comprising a targeted therapeutic fusion protein comprising alpha-N-acetylglucosaminidase (Naglu), a lysosomal targeting moiety, e.g., an IGF-II peptide, and a spacer peptide.

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