People Background Check
Find People:

Joseph F Krebs, Age 6111413 Cotulla Dr, Austin, TX 78739

Get Report
Known as:
Joseph K Krebs Joseph F Krebbs
Related to:
Nikki L Krebs Veronique J Krebs 27

Joseph Krebs Phones & Addresses

11413 Cotulla Dr, Austin, TX 78739 (512) 280-6773

6235 Buisson St, San Diego, CA 92122 (858) 453-6972

La Jolla, CA

Durham, NC

Del Mar, CA

11413 Cotulla Dr, Austin, TX 78739 (512) 689-6158

Work

Position: Professional/Technical

Mentions for Joseph F Krebs

Joseph Krebs resumes & CV records

Resumes

Joseph Krebs Photo 41

Joseph Krebs

Joseph Krebs Photo 42

Joseph Krebs

Joseph Krebs Photo 43

Joseph Krebs

Joseph Krebs Photo 44

Director, Protein Chemistry And Engineering At Bioo Scientific

Location:
Austin, Texas Area
Industry:
Biotechnology
Joseph Krebs Photo 45

Joseph Krebs

Location:
United States

Publications & IP owners

Us Patents

Methods For Detecting Membrane Derived Caspase Activity And Modulators Thereof

US Patent:
6391575, May 21, 2002
Filed:
Mar 5, 1999
Appl. No.:
09/263590
Inventors:
Lawrence C. Fritz - Rancho Santa Fe CA
Joseph F. Krebs - San Diego CA
Assignee:
IDUN Pharmaceuticals, Inc. - San Diego CA
International Classification:
C12Q 137
US Classification:
435 23, 435219, 435 772
Abstract:
Provided are methods for detecting membrane derived apoptotic activity. In one embodiment, the present invention provides methods for identifying membrane derived caspase activity. In other embodiments, drug discovery methods are provided for screening compounds that inhibit or enhance membrane derived caspase activity. In the various embodiments, heavy membrane fractions are utilized for the screening methodologies described herein.

Membrane Derived Caspase-3, Compositions Comprising The Same And Methods Of Use Therefor

US Patent:
6762045, Jul 13, 2004
Filed:
Mar 20, 2002
Appl. No.:
10/103448
Inventors:
Joseph F. Krebs - San Diego CA
Anupama Srinivasan - Carlsbad CA
Lawrence C. Fritz - Rancho Santa Fe CA
Joe C. Wu - San Diego CA
Assignee:
Idun Pharmaceuticals, Inc. - San Diego CA
International Classification:
C12N 964
US Classification:
435226, 435183, 435219, 435212, 4352523, 4353201, 435325, 435410, 435 6, 435348, 4352542, 536 231, 536 232, 536 235
Abstract:
Provided are isolated nucleic acids encoding a novel membrane derived caspase-3 and polypeptides expressed therefrom. In one embodiment, the nucleic acid expression vectors that produce membrane derived caspase-3 polypeptide may be introduced into host cells as a gene delivery vehicle. In other embodiments, methods are provided for treating pathological disorders caused by altered apoptosis, such as autoimmune disease, cancer, viral infections, and bacterial infections. Another aspect of the invention is the use of the isolated nucleic acid encoding membrane derived caspase-3 and polypeptides expressed therefrom as a means for promoting or inhibiting programmed cell death.

Low-Cost Production Of Peptides

US Patent:
7595173, Sep 29, 2009
Filed:
Oct 22, 2004
Appl. No.:
10/971444
Inventors:
Joseph F. Krebs - Austin TX, US
Paul S. Zorner - Carlsbad CA, US
Ian A. Tomlinson - Midland MI, US
Assignee:
Dow Global Technologies Inc. - Midland MI
International Classification:
C12P 21/06
C07H 21/04
C07K 5/06
US Classification:
435 691, 43525234, 435212, 435471, 530330, 530331, 536 232
Abstract:
The subject invention relates to a low cost method of producing peptides, including antimicrobial peptides (AMPs), by using microbes. The subject methods enable greatly improved yields of the peptide/AMP as compared to those heretofore known in the art. The subject methods also surprisingly enable the use of to produce AMPs and other peptides. There are several components of the subject invention, which can be used alone or in combination. The subject invention provides for the production of peptides/AMPs in concatemeric precursors. The subject invention also provides novel methods of assembling monomers into multimers, and of cleaving the multimers to yield active monomers. The subject invention also relates to the use of these multimers fused to carrier peptides to produce fusion proteins. Preferably, both the multimers and the fusion proteins (multimers with the carrier polypeptides) lack charge balancing. It has been surprisingly determined that it is not necessary to offset the positive charges of multiple copies of AMPs in multimeric constructs.

Methods And Compositions Concerning Sirna's As Mediators Of Rna Interference

US Patent:
8058255, Nov 15, 2011
Filed:
Jun 15, 2009
Appl. No.:
12/484948
Inventors:
Lance P. Ford - Austin TX, US
Joseph Krebs - Austin TX, US
Assignee:
Applied Biosystems, LLC - Carlsbad CA
International Classification:
A01N 43/04
A61K 31/70
US Classification:
514 44A
Abstract:
The present invention concerns an isolated siRNA of from about 5 to about 20 nucleotides that mediates RNA interference. Also disclosed are methods of reducing expression of a target gene in a cell comprising obtaining at least one siRNA of 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, or 20 basepairs in length; and delivering the siRNA into the cell. The siRNAs can be chemically synthesized RNA or an analog of a naturally occurring RNA.

Method For The Detection Of Melamine

US Patent:
8637269, Jan 28, 2014
Filed:
Jul 9, 2010
Appl. No.:
12/833580
Inventors:
Joseph Francis Krebs - Austin TX, US
Assignee:
Bioo Scientific Corporation - Austin TX
International Classification:
C12Q 1/34
US Classification:
435 18, 544203
Abstract:
Melamine is a common industrial chemical contaminant which should be absent from food and feed supplies due to melamine's toxicity. Provided is a method to assess the presence of melamine in samples prepared from compositions. The method may include using a microbial enzyme called melamine deaminase which hydrolyzes melamine to ammeline and ammonia. The method may include assessing the presence of any ammonia produced from an enzymatic reaction between the sample and the enzyme.

Methods For Detecting Membrane Derived Caspase Activity And Modulators Thereof

US Patent:
2002009, Jul 11, 2002
Filed:
Jan 8, 2002
Appl. No.:
10/042484
Inventors:
Lawrence Fritz - Rancho Santa Fe CA, US
Joseph Krebs - San Diego CA, US
Assignee:
Idun Pharmaceuticals, Inc. - San Diego CA
International Classification:
C12Q001/37
US Classification:
435/023000
Abstract:
Provided are methods for detecting membrane derived apoptotic activity. In one embodiment, the present invention provides methods for identifying membrane derived caspase activity. In other embodiments, drug discovery methods are provided for screening compounds that inhibit or enhance membrane derived caspase activity. In the various embodiments, heavy membrane fractions are utilized for the screening methodologies described herein.

Membrane Derived Caspase-3, Compositions Comprising The Same And Methods Of Use Therefor

US Patent:
2002019, Dec 26, 2002
Filed:
Mar 26, 2002
Appl. No.:
10/108929
Inventors:
Joseph Krebs - San Diego CA, US
Anupama Srinivasan - Carlsbad CA, US
Lawrence Fritz - Rancho Santa Fe CA, US
Joe Wu - San Diego CA, US
Assignee:
IDUN Pharmaceuticals, Inc. - San Diego CA
International Classification:
C12N009/64
C07H021/04
C12N001/18
C12N005/06
C12P021/02
C12N001/21
US Classification:
435/226000, 435/320100, 435/325000, 435/252300, 435/348000, 435/254200, 536/023200, 435/069100
Abstract:
Provided are isolated nucleic acids encoding a novel membrane derived caspase-3 and polypeptides expressed therefrom. In one embodiment, the nucleic acid expression vectors that produce membrane derived caspase-3 polypeptide may be introduced into host cells as a gene delivery vehicle. In other embodiments, methods are provided for treating pathological disorders caused by altered apoptosis, such as autoimmune disease, cancer, viral infections, and bacterial infections. Another aspect of the invention is the use of the isolated nucleic acid encoding membrane derived caspase-3 and polypeptides expressed therefrom as a means for promoting or inhibiting programmed cell death.

Methods And Compositions Concerning Sirna's As Mediators Of Rna Interference

US Patent:
2006014, Jun 29, 2006
Filed:
Dec 23, 2004
Appl. No.:
11/020560
Inventors:
Lance Ford - Austin TX, US
Joseph Krebs - Austin TX, US
International Classification:
A61K 48/00
C12Q 1/68
C07H 21/02
US Classification:
514044000, 435006000, 536023100
Abstract:
The present invention concerns an isolated siRNA of from about 5 to about 20 nucleotides that mediates RNA interference. Also disclosed are methods of reducing expression of a target gene in a cell comprising obtaining at least one siRNA of 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, or 20 basepairs in length; and delivering the siRNA into the cell. The siRNAs can be chemically synthesized RNA or an analog of a naturally occurring RNA.

Possible Relatives

Aaron L Krebs  Denise M Krebs  Dennis D Krebs  Donna J Krebs  Emily M Krebs  Evelyn E Krebs  Floyd A Krebs  Joseph C Last  Joseph S Stan  Joseph M Standish 

NOTICE: You may not use PeopleBackgroundCheck or the information it provides to make decisions about employment, credit, housing or any other purpose that would require Fair Credit Reporting Act (FCRA) compliance. PeopleBackgroundCheck is not a Consumer Reporting Agency (CRA) as defined by the FCRA and does not provide consumer reports.