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Joseph Pontillo, Age 503617 Caminito Carmel Lndg, San Diego, CA 92130

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Frank Pontillo Adalyn L Pontillo Deborah Pontillo

Joseph Pontillo Phones & Addresses

3617 Caminito Carmel Lndg, San Diego, CA 92130 (858) 231-6233

5111 Providence Rd, San Diego, CA 92117

7455 Charmant Dr, San Diego, CA 92122

Los Angeles, CA

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Joseph Pontillo resumes & CV records

Resumes

Joseph Pontillo Photo 16

Senior Research Scientist At Vertex Pharmaceuticals

Location:
Greater San Diego Area
Industry:
Pharmaceuticals
Joseph Pontillo Photo 17

Joseph Pontillo

Joseph Pontillo Photo 18

Joseph Pontillo

Location:
United States

Publications & IP owners

Us Patents

Gonadotropin-Releasing Hormone Receptor Antagonists And Methods Relating Thereto

US Patent:
6740656, May 25, 2004
Filed:
Aug 2, 2002
Appl. No.:
10/211993
Inventors:
Joseph Pontillo - San Diego CA
Chen Chen - San Diego CA
Assignee:
Neurocrine Biosciences, Inc. - San Diego CA
International Classification:
C07D49804
US Classification:
5142592, 544282
Abstract:
GnRH receptor antagonists are disclosed which have utility in the treatment of a variety of sex-hormone related conditions in both men and women. The compounds of this invention have the structure: wherein A, R , R , R , R , R , R , R , and n are as defined herein, including stereoisomers, prodrugs and pharmaceutically acceptable salts thereof. Also disclosed are compositions containing a compound of this invention in combination with a pharmaceutically acceptable carrier, as well as methods relating to the use thereof for antagonizing gonadotropin-releasing hormone in a subject in need thereof.

Gonadotropin-Releasing Hormone Receptor Antagonists And Methods Relating Thereto

US Patent:
6951858, Oct 4, 2005
Filed:
Nov 10, 2003
Appl. No.:
10/705762
Inventors:
Joseph Pontillo - San Diego CA, US
Zhiqiang Guo - San Diego CA, US
Dongpei Wu - San Diego CA, US
Assignee:
Neurocrine Biosciences, Inc. - San Diego CA
International Classification:
C07D253/075
A61K031/53
A61P015/00
A61P015/08
A61P015/018
US Classification:
514242, 544182
Abstract:
GnRH receptor antagonists are disclosed which have utility in the treatment of a variety of sex-hormone related conditions in both men and women. The compounds of this invention have the structure: wherein R, R, R, R, R, R, and n are as defined herein, including stereoisomers, prodrugs and pharmaceutically acceptable salts thereof. Also disclosed are compositions containing a compound of this invention in combination with a pharmaceutically acceptable carrier, as well as methods relating to the use thereof for antagonizing gonadotropin-releasing hormone in a subject in need thereof.

Melanin-Concentrating Hormone Receptor Antagonists And Compositions And Methods Related Thereto

US Patent:
7067509, Jun 27, 2006
Filed:
Mar 8, 2004
Appl. No.:
10/797487
Inventors:
Val Goodfellow - Encinitas CA, US
Martin Rowbottom - La Jolla CA, US
Brian P Dyck - San Diego CA, US
Junko Tamiya - Oceanside CA, US
Mingzhu Zhang - San Diego CA, US
Jonathan Grey - San Diego CA, US
Troy D Vickers - San Diego CA, US
Mehrak Kiankarimi - San Diego CA, US
Warren Wade - San Diego CA, US
Sarah Clough - San Diego CA, US
Joseph Pontillo - San Diego CA, US
Dongpei Wu - San Diego CA, US
Assignee:
Neurocrine Biosciences, Inc. - San Diego CA
International Classification:
A61K 31/397
A61K 31/401
A61K 31/4025
C07D 207/14
US Classification:
51421018, 514422, 548524, 548953
Abstract:
Melanin-concentrating hormone (MCH) receptor antagonists are disclosed having utility for the treatment of MCH receptor-based disorders such as obesity. The compounds of this invention have the following structure:.

Monoamine Re-Uptake Inhibitors And Methods Relating Thereto

US Patent:
7378552, May 27, 2008
Filed:
Jun 7, 2006
Appl. No.:
11/422843
Inventors:
Joseph Pontillo - San Diego CA, US
Yinghong Gao - San Diego CA, US
Warren S. Wade - San Diego CA, US
Dongpei Wu - San Diego CA, US
Wendy K. Eccles - San Diego CA, US
Assignee:
Neurocrine Biosciences, Inc. - San Diego CA
International Classification:
C07C 255/00
A61K 31/135
US Classification:
564336, 558411, 514649
Abstract:
Monoamine re-uptake inhibitors and more specifically serotonin and noradrenaline re-uptake inhibitors are disclosed that have utility in the treatment of disorders of the central or peripheral nervous system in both men and women. The compounds of this invention have the structure:.

Heterocyclic Chromene-Spirocyclic Piperidine Amides As Modulators Of Ion Channels

US Patent:
8598164, Dec 3, 2013
Filed:
May 6, 2011
Appl. No.:
13/102335
Inventors:
Edward Adam Kallel - Escondido CA, US
Mark Thomas Miller - San Diego CA, US
Joseph Pontillo - San Diego CA, US
Vijayalaksmi Arumugam - San Marcos CA, US
Nicole Hilgraf - San Diego CA, US
Jason McCartney - Cardiff by the Sea CA, US
Peter Diederik Jan Grootenhuis - San Diego CA, US
Corey Anderson - San Diego CA, US
Mehdi Numa - San Diego CA, US
Bryan A. Frieman - San Diego CA, US
Brian Richard Bear - Oceanside CA, US
Assignee:
Vertex Pharmaceuticals Incorporated - Cambridge MA
International Classification:
C07D 491/22
C07D 498/22
A61K 31/5386
A61K 31/438
US Classification:
5142295, 544 71, 546 17, 514278
Abstract:
The invention relates to heterocyclic chromene-spirocyclic piperidine amides useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.

Gonadotropin-Releasing Hormone Receptor Antagonists And Methods Relating Thereto

US Patent:
2003011, Jun 19, 2003
Filed:
Aug 2, 2002
Appl. No.:
10/211992
Inventors:
Joseph Pontillo - San Diego CA, US
Zhiqiang Guo - San Diego CA, US
Dongpei Wu - San Diego CA, US
Assignee:
Neurocrine Biosciences, Inc. - San Diego CA
International Classification:
A61K031/53
C07D253/00
C 07D 4 3/02
US Classification:
514/242000, 544/182000
Abstract:
GnRH receptor antagonists are disclosed which have utility in the treatment of a variety of sex-hormone related conditions in both men and women. The compounds of this invention have the structure: wherein R, R, R, R, R, R, and n are as defined herein, including stereoisomers, prodrugs and pharmaceutically acceptable salts thereof. Also disclosed are compositions containing a compound of this invention in combination with a pharmaceutically acceptable carrier, as well as methods relating to the use thereof for antagonizing gonadotropin-releasing hormone in a subject in need thereof.

Ligands Of Melanocortin Receptors And Compositions And Methods Related Thereto

US Patent:
2003015, Aug 21, 2003
Filed:
Oct 9, 2002
Appl. No.:
10/268923
Inventors:
Brian Dyck - San Diego CA, US
Val Goodfellow - Encinitas CA, US
Teresa Phillips - San Diego CA, US
Jessica Parker - San Diego CA, US
Xiaohu Zhang - San Diego CA, US
Chen Chen - San Diego CA, US
Joe Tran - San Marcos CA, US
Joseph Pontillo - San Diego CA, US
Fabio Tucci - San Diego CA, US
Assignee:
Neurocrine Biosciences Inc. - San Diego CA
International Classification:
A61K031/496
A61K031/495
C 07D 4 3/02
C07D241/04
US Classification:
514/253010, 514/255010, 544/386000, 544/360000
Abstract:
Compounds which function as melanocortin receptor ligands and having utility in the treatment of melanocortin receptor-based disorders. The compounds have the following structure (I): including stereoisomers, prodrugs, and pharmaceutically acceptable salts thereof, wherein A, m, n, R, R, R, R, R, R, RW, W, W, W, Y, Y, Yand Yare as defined herein. Pharmaceutical compositions containing a compound of structure (I), as well as methods relating to the use thereof, are also disclosed.

Ligands Of Melanocortin Receptors And Compositions And Methods Related Thereto

US Patent:
2004005, Mar 18, 2004
Filed:
May 9, 2003
Appl. No.:
10/434803
Inventors:
Joseph Pontillo - San Diego CA, US
Dragan Marinkovic - Del Mar CA, US
Marion Lanier - San Diego CA, US
Joe Tran - San Marcos CA, US
Melissa Arellano - San Diego CA, US
Jessica Parker - San Diego CA, US
Jodie Nelson - San Diego CA, US
Chen Chen - San Diego CA, US
Fabio Tucci - San Diego CA, US
Caroline Chen - San Diego CA, US
Wanlong Jiang - San Diego CA, US
Nicole White - San Diego CA, US
Assignee:
Neurocrine Biosciences, Inc. - San Diego CA
International Classification:
A61K031/506
A61K031/497
A61K031/501
A61K031/496
C 07D 4 3/02
US Classification:
514/252020, 514/252110, 514/252140, 544/238000, 544/295000, 544/357000, 544/360000, 514/253010
Abstract:
Compounds which function as melanocortin receptor ligands and having utility in the treatment of melanocortin receptor-based disorders. The compounds have the following structure (I): including stereoisomers, prodrugs, and pharmaceutically acceptable salts thereof, wherein Ar, R, R, R, R, R, R, R, R, R, q, r, X, Y, Y, Yand Yare as defined herein. Pharmaceutical compositions containing a compound of structure (I), as well as methods relating to the use thereof, are also disclosed.

Possible Relatives

Emilio A Pontillo  James J Pontillo  John A Pontillo  Maria A Pontillo  Peter W Pontillo  Joseph C Last  Joseph S Stan  Joseph M Standish  Joseph M Standley  Joseph L White 

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