Inventors:
Brian Dyck - San Diego CA, US
Val Goodfellow - Encinitas CA, US
Teresa Phillips - San Diego CA, US
Jessica Parker - San Diego CA, US
Xiaohu Zhang - San Diego CA, US
Chen Chen - San Diego CA, US
Joe Tran - San Marcos CA, US
Joseph Pontillo - San Diego CA, US
Fabio Tucci - San Diego CA, US
Assignee:
Neurocrine Biosciences Inc. - San Diego CA
International Classification:
A61K031/496
A61K031/495
C 07D 4 3/02
C07D241/04
US Classification:
514/253010, 514/255010, 544/386000, 544/360000
Abstract:
Compounds which function as melanocortin receptor ligands and having utility in the treatment of melanocortin receptor-based disorders. The compounds have the following structure (I): including stereoisomers, prodrugs, and pharmaceutically acceptable salts thereof, wherein A, m, n, R, R, R, R, R, R, RW, W, W, W, Y, Y, Yand Yare as defined herein. Pharmaceutical compositions containing a compound of structure (I), as well as methods relating to the use thereof, are also disclosed.