Joseph A Scibona, Age 918340 Cochise Rd, Colorado Springs, CO 80908

7327443, Feb 5, 2008

Dec 29, 2004

10/905353

Joseph A. Scibona - Littleton CO, US
Shannon Durkee - Westminster CO, US

Gambro BCT, Inc - Lakewood CO

G01N 33/48

356 39

The invention relates to apparatus for controlling the processing of blood into blood components, particularly components for stroboscopic LED light sources for centrifuges. The stroboscopic apparatus comprises a first light source with reflective surfaces spaced around a central illumination axis, and light-emitting diodes spaced away from the axis radially outward from the reflective surfaces. An additional light source comprises a modified parabolic reflector surrounding a light emitting diode, the parabolic reflector having walls spaced outwardly from an axis of symmetry such that focal points fall radially outwardly from a center of the LED, forming a circular focal area. A controller that energizes the diodes for selected periods of time comprises a pair of switches connected in series, with an LED connected between the switches. One of the switches is connected to ground and is closed at the end of a period of illumination.

7355685, Apr 8, 2008

Oct 5, 2007

11/867816

Joseph A. Scibona - Littleton CO, US
Shannon Durkee - Phoenix AZ, US

Gambro BCT, Inc. - Lakewood CO

G01N 33/48

356 39

The invention relates to apparatus for controlling the processing of blood into blood components, particularly components for stroboscopic LED light sources for centrifuges. The stroboscopic apparatus comprises a first light source with reflective surfaces spaced around a central illumination axis, and light-emitting diodes spaced away from the axis radially outward from the reflective surfaces. An additional light source comprises a modified parabolic reflector surrounding a light emitting diode, the parabolic reflector having walls spaced outwardly from an axis of symmetry such that focal points fall radially outwardly from a center of the LED, forming a circular focal area. A controller that energizes the diodes for selected periods of time comprises a pair of switches connected in series, with an LED connected between the switches. One of the switches is connected to ground and is closed at the end of a period of illumination.

7422693, Sep 9, 2008

Jul 1, 2004

10/884877

Lee F. Carter - Lakewood CO, US
Jeremy P. Kolenbrander - Brighton CO, US
James R. Ladtkow - Broomfield CO, US
Joseph A. Scibona - Littleton CO, US
Jeffrey A. Steward - Lakewood CO, US
Chris Fletcher - Superior CO, US

Caridianbct, Inc. - Lakewood CO

B04B 9/10

210745, 210 94, 2105121, 210787, 250573, 250574, 494 1, 494 7, 494 10, 494 37

The invention relates generally to methods of monitoring and controlling the processing of blood and blood samples, particularly the separation of blood and blood samples into its components. In one aspect, the invention relates to optical methods, devices and device components for measuring two-dimensional distributions of transmitted light intensities, scattered light intensities or both from a separation chamber of a density centrifuge. In embodiment, two-dimensional distributions of transmitted light intensities, scattered light intensities or both measured by the methods of the present invention comprise images of a separation chamber or component thereof, such as an optical cell of a separation chamber. In another aspect, the present invention relates to multifunctional monitoring and control systems for blood processing, particularly blood processing via density centrifugation. Feedback control systems are provided wherein two-dimensional distributions of transmitted light intensities, scattered light intensities or both are measured, processed in real time and are used as the basis of output signals for controlling blood processing.

7605388, Oct 20, 2009

Jul 7, 2008

12/168192

Lee F. Carter - Lakewood CO, US
Jeremy P. Kolenbrander - Brighton CO, US
James R. Ladtkow - Broomfield CO, US
Joseph A. Scibona - Littleton CO, US
Jeffrey A. Steward - Lakewood CO, US
Chris Fletcher - Superior CO, US

CaridianBCT, Inc. - Lakewood CO

G01N 15/06
G01N 21/49
G01N 21/85

250573, 2502222, 356 39, 73 6148

The invention relates to an optical cell for a separation chamber of a density centrifuge blood processing system for separating fluid components comprising an extraction chamber having a first external optical surface for transmitting at least a portion of an incident optical beam; and an extraction port having an axial bore for passing fluid components and a first external optical surface for transmitting at least a portion of the incident optical beam; wherein said first external optical surface of said extraction chamber and said first external optical surface of said extraction port are both positioned within the depth of field of a light collection element.

7906771, Mar 15, 2011

Sep 17, 2009

12/561419

Lee F. Carter - Lakewood CO, US
Jeremy P. Kolenbrander - Brighton CO, US
James R. Ladtkow - Broomfield CO, US
Joseph A. Scibona - Littleton CO, US
Jeffrey A. Steward - Lakewood CO, US
Chris Fletcher - Superior CO, US

CaridianBCT, Inc. - Lakewood CO

B04B 13/00

250573, 494 1, 210745

The invention relates generally to methods of monitoring and controlling the processing of blood and blood samples, particularly the separation of blood and blood samples into its components. In one aspect, the invention relates to optical methods for measuring two-dimensional distributions of transmitted light intensities, scattered light intensities or both from a separation chamber of a density centrifuge. The method may include performing first and second measurements of an operating condition; analyzing the first and second measurements using a predictive data analysis algorithm; comparing the predicted operating condition to a desired operating condition; and adjusting at least one setting.

7943916, May 17, 2011

Sep 17, 2009

12/561479

Lee F. Carter - Lakewood CO, US
Jeremy P. Kolenbrander - Brighton CO, US
James R. Ladtkow - Broomfield CO, US
Joseph A. Scibona - Littleton CO, US
Jeffrey A. Steward - Lakewood CO, US
Chris Fletcher - Superior CO, US

CaridianBCT, Inc. - Lakewood CO

B01D 37/04

250573, 2502222, 356 39, 73 48

The invention relates generally to methods of monitoring and controlling the processing of blood and blood samples, particularly the separation of blood and blood samples into its components with a two-dimensional optical measurement and control device. The method may comprise the steps of providing a blood processing system comprising a density centrifuge blood processing system and an elutriation blood processing system; filling the elutriation blood processing system with a desired component; measuring a cellular flux of cells entering the elutriation blood processing system with a two-dimensional optical control system; and flushing the elutriation blood processing system.

8057376, Nov 15, 2011

Sep 30, 2008

12/241441

James R. Ladtkow - Broomfield CO, US
Joseph A. Scibona - Littleton CO, US
Jeremy Kolenbrander - Brighton CO, US

CaridianBCT, Inc. - Lakewood CO

B04B 15/00
G02B 5/02

494 10, 359599, 359613

A centrifugal blood separation apparatus having an optical camera control system with a focused, stationary light source. A diffusion plate mounted on a rotor, rather than on or near the light source, allows an intense light beam to be transmitted from the light source to the rotor and then diffused at the rotor across an observation region. Different characteristics of a diffusion surface allow different lighting regions within the observation region. The diffusion plate has upper and lower plates with a diffusion surface sealed between the plates. This prevents degradation or contamination of the diffusion surface by abrasion, dirt, blood components or other materials that might incidentally contact the diffusion surface.

8241196, Aug 14, 2012

Dec 4, 2009

12/631289

Joseph A. Scibona - Littleton CO, US

Terumo BCT, Inc. - Lakewood CO

B04B 15/00

494 10, 494 43

The invention relates to apparatus for controlling the processing of blood into blood components, particularly components for stroboscopic LED light sources for centrifuges. A digital control circuit controls a high amperage linear voltage regulator. The voltage regulator charges a capacitor bank, which in turn powers LED light sources. The digital control circuit comprises an N-channel switched mode FET. The switched mode FET receives a pulsed digital signal from the microprocessor controlling the blood processing apparatus. A by-pass resistor in parallel with the FET allows most of the current to flow past the FET, thus minimizes heating of the FET. The performance of the FET, therefore, remains stable despite extended use of the apparatus.