Larry Dean Overman, Age 781107 Summit St, Yankton, SD 57078

Larry Overman Phones & Addresses

Yankton, SD

Overland Park, KS

Corona del Mar, CA

Beatrice, NE

Lincoln, NE

Enfield, CT

Sparks, NV

Truckee, CA

Denver, CO

San Francisco, CA

Washoe, NV

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Resumes

Larry Overman Photo 23

Security Officer

Location:
815 Geary St, San Francisco, CA 94109
Industry:
Marketing And Advertising
Work:
Tahoe Donner Association
Security Officer
Languages:
English
Larry Overman Photo 24

Larry Overman

Publications & IP owners

Wikipedia

Larry Overman Photo 27

Larry E. Overman

Larry E. Overman is Distinguished Professor of Chemistry at the University of California, Irvine. He was born in Chicago in 1943. Overman obtained a B.A. ...

Us Patents

Method For Preparing Crambescidin Core Acid Intermediates And Their Use For Preparing Crambescidin Alkaloid Analogs As Therapeutic Agents

US Patent:
2003017, Sep 18, 2003
Filed:
Sep 24, 2002
Appl. No.:
10/255994
Inventors:
Larry Overman - Corona del Mar CA, US
Frank Stappenbeck - San Francisco CA, US
Andrew McDonald - San Francisco CA, US
Zachary Aron - Irvine CA, US
Assignee:
The Regents of the University of California
International Classification:
A61K031/519
C07D487/14
US Classification:
544/231000, 514/257000
Abstract:
The invention provides methods to synthesize zwitterionic pentacyclic crambescidin core intermediates having the carboxylate side chain in the natural axial orientation, and a range of crambescidin alkaloid analogs.

Method For Improved Chemical Synthesis Of Guanidinium Alkaloids

US Patent:
2005023, Oct 27, 2005
Filed:
Mar 30, 2004
Appl. No.:
10/815023
Inventors:
Larry Overman - Corona del Mar CA, US
Frank Stappenbeck - San Francisco CA, US
Andrew McDonald - Irvine CA, US
International Classification:
A61K031/519
C07D491/14
US Classification:
514257000, 544231000
Abstract:
Improved methods for convergent, total enantioselective synthesis of guanidinium alkaloid compounds including ones having cis- or -trans-1-oxo-and 1-iminohexahydropyrrolo [1,2c]pyrimidine units including, 13,14,15-isocrambescidin 800, crambescidin 800 and ptilomycalin A, for use as therapeutic agents having antifungal and/or antiviral and/or antitumor activity are provided. Methods for preparing novel pentacyclic intermediates for the preparation of the crambescidin/ptilomycalin family of guanidinium alkaloids and congeners are also disclosed.

Synthesis Of Indolizidines Related To The Carditonic Pumiliotoxin A Alkaloids

US Patent:
4675325, Jun 23, 1987
Filed:
Jun 21, 1984
Appl. No.:
6/622790
Inventors:
Larry E. Overman - Corona Del Mar CA
Fumitaka Ito - Sendai, JP
Assignee:
The Regents of the University of California - Berkeley CA
International Classification:
A61K 31475
C07D22102
US Classification:
514299
Abstract:
A method of making dendrobatid alkaloids with the formula ##STR1## in which A is either CH. sub. 3 or H, and n is an integer from 1-9, and R is CH. sub. 2 OH, CHO, ##STR2## and R. sub. 1 and R. sub. 2 are alkyl groups; and the use of such alkaloids to treat cardiovascular illness.

Selective Antagonists For Gaba.sub.rho Receptor

US Patent:
5627169, May 6, 1997
Filed:
Jul 20, 1994
Appl. No.:
8/277735
Inventors:
Ricardo Miledi - Irvine CA
Larry E. Overman - Corona del Mar CA
Yoshinori Murata - Irvine CA
Richard M. Woodward - Aliso Viejo CA
Assignee:
The Regents of The University of California - Oakland CA
International Classification:
C07F 958
A61K 31675
US Classification:
514 89
Abstract:
Novel phosphinic and phosphonic acid derivatives of pyridine, pyrrole and azepine with utility as antagonists of the GABA. sub. rho receptor are disclosed. These compounds have utility as modulators of the excitability of the central nervous system as mediated by their ability to specifically act on closed-channel binding sites of GABA. sub. rho receptors.

Use Of H3K9Me3 Modulation For Enhancing Cognitive Function

US Patent:
2023005, Feb 23, 2023
Filed:
Mar 17, 2022
Appl. No.:
17/697893
Inventors:
- OAKLAND CA, US
Larry E. OVERMAN - Corona del Mar CA, US
Shikha SNIGDHA - Long Beach CA, US
International Classification:
A61K 31/548
C07D 513/18
A61K 45/06
A61K 31/27
A61K 31/445
A61K 31/473
A61P 25/28
A61P 25/22
A61P 25/00
A61K 31/202
A61K 31/522
Abstract:
Use of H3K9me3 modulation for enhancing cognitive function and treating anxiety related disorders is presented. A composition is administered to the subject comprising a therapeutically effective amount of a SUV39H1 inhibitor comprising analogs of ETP69. The therapeutically effective amount is effective in treating cognitive dysfunction in aging and age-related disorders.

Dithio Etp Derivatives

US Patent:
2021011, Apr 22, 2021
Filed:
Sep 23, 2020
Appl. No.:
17/030073
Inventors:
- Duarte CA, US
- Oakland CA, US
Larry Eugene Overman - Corona Del Mar CA, US
Brad Loertscher - Portage MI, US
International Classification:
C07D 513/18
A61K 31/706
C07D 487/04
A61K 31/548
C07D 401/12
A61K 45/06
C07D 513/08
A61P 35/00
Abstract:
Disclosed herein, inter alia, are compositions and methods of using the same for the treatment of cancer.

Use Of H3K9Me3 Modulation For Enhancing Cognitive Function

US Patent:
2021010, Apr 15, 2021
Filed:
Oct 16, 2020
Appl. No.:
17/072539
Inventors:
- OAKLAND CA, US
Larry E. OVERMAN - Corona del Mar CA, US
Shikha SNIGDHA - Long Beach CA, US
International Classification:
A61K 31/548
C07D 513/18
A61K 45/06
A61K 31/27
A61K 31/445
A61K 31/473
A61P 25/28
A61P 25/22
A61P 25/00
A61K 31/202
A61K 31/522
Abstract:
Use of H3K9me3 modulation for enhancing cognitive function and treating anxiety related disorders is presented. A composition is administered to the subject comprising a therapeutically effective amount of a SUV39H1 inhibitor comprising analogs of ETP69. The therapeutically effective amount is effective in treating cognitive dysfunction in aging and age-related disorders.

Use Of H3K9Me3 Modulation For Enhancing Cognitive Function

US Patent:
2019020, Jul 11, 2019
Filed:
Mar 15, 2019
Appl. No.:
16/354996
Inventors:
- OAKLAND CA, US
Larry E. OVERMAN - Corona del Mar CA, US
Shikha SNIGDHA - Long Beach CA, US
International Classification:
A61K 31/548
A61P 25/28
A61K 31/473
A61K 31/445
A61K 31/27
A61P 25/00
A61K 31/522
A61K 31/202
A61P 25/22
C07D 513/18
A61K 45/06
Abstract:
Use of H3K9me3 modulation for enhancing cognitive function and treating anxiety related disorders is presented. A composition is administered to the subject comprising a therapeutically effective amount of a SUV39H1 inhibitor comprising analogs of ETP69. The therapeutically effective amount is effective in treating cognitive dysfunction in aging and age-related disorders.

Isbn (Books And Publications)

Organic Reactions

Author:
Larry E. Overman
ISBN #:
0470041455

Organic Reactions

Author:
Larry E. Overman
ISBN #:
0470041536

Organic Syntheses

Author:
Larry E. Overman
ISBN #:
0470095695

Organic Reactions

Author:
Larry E. Overman
ISBN #:
0470139633

Organic Reactions

Author:
Larry E. Overman
ISBN #:
0470223979

Organic Reactions

Author:
Larry E. Overman
ISBN #:
0471064459

Organic Reactions

Author:
Larry E. Overman
ISBN #:
0471105902

Organic Reactions

Author:
Larry E. Overman
ISBN #:
0471176559

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