Leslie B Naggiar, Age 70479 Iroquois Ct, Suffern, NY 10901
Leslie Naggiar Phones & Addresses
479 Iroquois Ct, Suffern, NY 10901 (845) 368-1505
Monroe Township, NJ
Hackensack, NJ
Yolo, CA
Work
Position:
Clerical/White Collar
Education
Degree:
Associate degree or higher
Mentions for Leslie B Naggiar
Publications & IP owners
Us Patents
Methods For Producing Biological Substances In Pigment-Deficient Mutants Of Bacillus Cells
US Patent:
2010033, Dec 30, 2010
Filed:
Feb 10, 2010
Appl. No.:
12/703550
Inventors:
Maria Tang - Fairfield CA, US
Alan Sloma - Davis CA, US
Leslie Naggiar - Suffern NY, US
David Sternberg - Davis CA, US
Linda Sternberg - Davis CA, US
Regine Behr - Roseville CA, US
Alan Sloma - Davis CA, US
Leslie Naggiar - Suffern NY, US
David Sternberg - Davis CA, US
Linda Sternberg - Davis CA, US
Regine Behr - Roseville CA, US
Assignee:
Novozymes, Inc. - Davis CA
International Classification:
C12P 21/00
C12N 1/21
C12N 15/74
C12N 1/21
C12N 15/74
US Classification:
435 691, 43525231, 435471
Abstract:
The present invention relates to methods of producing a heterologous biological substance, comprising: (a) cultivating a mutant of a parent cell under conditions conducive for the production of the heterologous biological substance, wherein (i) the mutant cell comprises a first nucleic acid sequence directing synthesis of the heterologous biological substance and a second nucleic acid sequence comprising a modification of at least one of the genes cypX and yvmC, which are involved in the production of a red pigment, and (ii) the mutant cell is deficient in the production of the red pigment compared to the parent cell when cultivated under the same conditions; and (b) recovering the heterologous biological substance from the cultivation medium. The present invention also relates to mutants of cells and methods for producing the mutants.
Methods For Producing Hyaluronan In A Recombinant Host Cell
US Patent:
2011001, Jan 20, 2011
Filed:
Sep 27, 2010
Appl. No.:
12/891548
Inventors:
Alan Sloma - Davis CA, US
Leslie Naggiar - Suffern NY, US
Regine Behr - Roseville CA, US
William Widner - Davis CA, US
Maria Tang - Fairfield CA, US
David Sternberg - Davis CA, US
Linda Sternberg - Davis CA, US
Stephen Brown - Davis CA, US
Leslie Naggiar - Suffern NY, US
Regine Behr - Roseville CA, US
William Widner - Davis CA, US
Maria Tang - Fairfield CA, US
David Sternberg - Davis CA, US
Linda Sternberg - Davis CA, US
Stephen Brown - Davis CA, US
Assignee:
Novozymes, Inc. - Davis CA
International Classification:
C12P 19/04
US Classification:
435101
Abstract:
The present invention relates to methods for producing a hyaluronic acid, comprising: (a) cultivating a host cell under conditions suitable for production of the hyaluronic acid, wherein the host cell comprises a nucleic acid construct comprising a hyaluronan synthase encoding sequence operably linked to a promoter sequence foreign to the hyaluronan synthase encoding sequence; and (b) recovering the hyaluronic acid from the cultivation medium. The present invention also relates to an isolated nucleic acid sequence encoding a hyaluronan synthase operon comprising a hyaluronan synthase gene and a UDP-glucose 6-dehydrogenase gene, and optionally one or more genes selected from the group consisting of a UDP-glucose pyrophosphorylase gene, UDP-N-acetylglucosamine pyrophosphorylase gene, and glucose-6-phosphate isomerase gene. The present invention also relates to isolated nucleic acid sequences encoding a UDP-glucose 6-dehydrogenase, UDP-glucose pyrophosphorylase, and UDP-N-acetylglucosamine pyrophosphorylase
Methods For Producing Hyaluronan In A Recombinant Host Cell
US Patent:
2011018, Aug 4, 2011
Filed:
Apr 11, 2011
Appl. No.:
13/084230
Inventors:
Alan Sloma - Davis CA, US
Regine Behr - Roseville CA, US
William Widner - Davis CA, US
Maria Tang - Fairfield CA, US
David Sternberg - Davis CA, US
Stephen Brown - Davis CA, US
Leslie Naggiar - Suffern NY, US
Linda Sternberg - Davis CA, US
Regine Behr - Roseville CA, US
William Widner - Davis CA, US
Maria Tang - Fairfield CA, US
David Sternberg - Davis CA, US
Stephen Brown - Davis CA, US
Leslie Naggiar - Suffern NY, US
Linda Sternberg - Davis CA, US
Assignee:
Novozymes, Inc. - Davis CA
International Classification:
C12P 19/04
US Classification:
435101
Abstract:
The present invention relates to methods for producing a hyaluronic acid, comprising: (a) cultivating a host cell under conditions suitable for production of the hyaluronic acid, wherein the host cell comprises a nucleic acid construct comprising a hyaluronan synthase encoding sequence operably linked to a promoter sequence foreign to the hyaluronan synthase encoding sequence; and (b) recovering the hyaluronic acid from the cultivation medium. The present invention also relates to an isolated nucleic acid sequence encoding a hyaluronan synthase operon comprising a hyaluronan synthase gene and a UDP-glucose 6-dehydrogenase gene, and optionally one or more genes selected from the group consisting of a UDP-glucose pyrophosphorylase gene, UDP-N-acetylglucosamine pyrophosphorylase gene, and glucose-6-phosphate isomerase gene. The present invention also relates to isolated nucleic acid sequences encoding a UDP-glucose 6-dehydrogenase, UDP-glucose pyrophosphorylase, and UDP-N-acetylglucosamine pyrophosphorylase
Methods For Producing Hyaluronan In A Recombinant Host Cell
US Patent:
2012014, Jun 14, 2012
Filed:
Feb 21, 2012
Appl. No.:
13/401663
Inventors:
Alan Sloma - Davis CA, US
Leslie Naggiar - Suffern NY, US
Regine Behr - Roseville CA, US
William Widner - Davis CA, US
Maria Tang - Fairfield CA, US
David Sternberg - Davis CA, US
Linda Sternberg - Davis CA, US
Stephen Brown - Davis CA, US
Leslie Naggiar - Suffern NY, US
Regine Behr - Roseville CA, US
William Widner - Davis CA, US
Maria Tang - Fairfield CA, US
David Sternberg - Davis CA, US
Linda Sternberg - Davis CA, US
Stephen Brown - Davis CA, US
Assignee:
Novozymes, Inc. - Davis CA
International Classification:
C12P 19/28
US Classification:
435 85
Abstract:
The present invention relates to methods for producing a hyaluronic acid, comprising: (a) cultivating a host cell under conditions suitable for production of the hyaluronic acid, wherein the host cell comprises a nucleic acid construct comprising a hyaluronan synthase encoding sequence operably linked to a promoter sequence foreign to the hyaluronan synthase encoding sequence; and (b) recovering the hyaluronic acid from the cultivation medium. The present invention also relates to an isolated nucleic acid sequence encoding a hyaluronan synthase operon comprising a hyaluronan synthase gene and a UDP-glucose 6-dehydrogenase gene, and optionally one or more genes selected from the group consisting of a UDP-glucose pyrophosphorylase gene, UDP-N-acetylglucosamine pyrophosphorylase gene, and glucose-6-phosphate isomerase gene. The present invention also relates to isolated nucleic acid sequences encoding a UDP-glucose 6-dehydrogenase, UDP-glucose pyrophosphorylase, and UDP-N-acetylglucosamine pyrophosphorylase
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