Lin TaoChicago, IL

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Chicago, IL

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Lin Tao

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Lin Tao

Location:
United States

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Us Patents

Novel Systems, Vectors, And Methods For Delivery Of Biomolecules To Eukaryotic Cells

US Patent:
2013007, Mar 28, 2013
Filed:
May 25, 2011
Appl. No.:
13/699593
Inventors:
Lin Tao - Chicago IL, US
Assignee:
The Board of Trustees of the University of Illinois - Urbana IL
International Classification:
A61K 47/46
US Classification:
4242041, 4241841, 424 934, 4351736, 435375, 4352521, 4353201
Abstract:
Embodiments described herein provide novel bacterial-based methods, systems, and delivery vehicles capable of delivering DNA, RNA, proteins, and other cargo into targeted mammalian cells, both in vitro and in vivo, with high efficiency. Delivery vehicles may be used to deliver molecules such as prophylactic or therapeutic proteins, DNA, shRNA, DNA vaccines, mucosal vaccines, modified viruses or viral components, and other bioactive molecules. Potential applications include gene therapy, wound healing therapies, cancer therapy, immune modulation, and research applications for which delivery of DNA, RNA, proteins, or other cargo into mammalian cells and tissues is required.

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