Lisa E Liss, Age 65170 Steinway Ave, Staten Island, NY 10314

5647369, Jul 15, 1997

Apr 19, 1996

8/634974

Steven P. Petrucelli - Cranbury NJ
Walter Welkowitz - Metuchen NJ
Lisa K. Liss - Dunellen NJ
Alan M. Smith - East Brunswick NJ
Stephen A. Orbine - Bernardsville NJ

Rutgers University - New Brunswick NJ

A61B 500

128672

Apparatus and methods for noninvasively measuring cardiovascular system parameters. According to a first preferred embodiment, the apparatus generates a time varying electrical voltage waveform having voltages corresponding to systolic and diastolic arterial pressures of the subject, the parameters being modelled by a lumped element electric circuit model analogous to the living subject's cardiovascular system, said circuit model including a systolic capacitor analogous to arterial compliance during systole, said apparatus comprising means for computing the value of said systolic capacitor from a measurement of an elapsed time between two voltage levels within a portion of said voltage waveform corresponding to systole, according to a predetermined criteria; and means for computing at least one said cardiovascular system parameter from said capacitor value. According to a second embodiment, a time-varying systolic arterial compliance is measured by measuring an arterial pulse pressure waveform. A third embodiment discloses a method of measuring cardiac output noninvasively from a cuff measurement of a patient's systolic minus diastolic blood pressure and a heart rate measurement.

5535753, Jul 16, 1996

Oct 4, 1994

8/317927

Steven P. Petrucelli - Cranbury NJ
Walter Welkowitz - Metuchen NJ
Lisa K. Liss - Dunellen NJ
Alan M. Smith - East Brunswick NJ
Stephen A. Orbine - Bernardsville NJ

Rutgers University - New Brunswick NJ

A61B 500

128672

Apparatus and methods for noninvasively measuring cardiovascular system parameters. According to a first preferred embodiment, the apparatus generates a time varying electrical voltage waveform having voltages corresponding to systolic and diastolic arterial pressures of the subject, the parameters being modelled by a lumped element electric circuit model analogous to the living subject's cardiovascular system, said circuit model including a systolic capacitor analogous to arterial compliance during systole, said apparatus comprising means for computing the value of said systolic capacitor from a measurement of an elapsed time between two voltage levels within a portion of said voltage waveform corresponding to systole, according to a predetermined criteria; and means for computing at least one said cardiovascular system parameter from said capacitor value. According to a second embodiment, a time-varying systolic arterial compliance is measured by measuring an arterial pulse pressure waveform. A third embodiment discloses a method of measuring cardiac output noninvasively from a cuff measurement of a patient's systolic minus diastolic blood pressure and a heart rate measurement.