Louis Begin DeceasedAlma, MI

Louis Begin Phones & Addresses

Alma, MI

Gaylord, MI

Rosemont, IL

Mentions for Louis Begin

Publications & IP owners

Us Patents

Substituted Phenylthioalkylamines And Compositions Thereof

US Patent:
4183927, Jan 15, 1980
Filed:
Sep 13, 1977
Appl. No.:
5/832848
Inventors:
Louis E. Begin - Midland MI
Robert J. Broersma - Noblesville IN
George D. Dickerson - Indianapolis IN
Joseph E. Dunbar - Midland MI
Assignee:
The Dow Chemical Company - Midland MI
International Classification:
C07D29510
A61K 31535
US Classification:
4242485
Abstract:
Novel substituted phenylthioalkylamines, salts and pharmaceutical compositions thereof wherein the sulfur may appear as a sulfide, sulfinyl or sulfonyl are disclosed as antithrombotic agents.

Method For Inhibiting Adp-Induced Platelet Aggregation Using Phenylthioalkylamines

US Patent:
4134996, Jan 16, 1979
Filed:
Sep 14, 1977
Appl. No.:
5/833125
Inventors:
Joseph E. Dunbar - Midland MI
Louis E. Begin - Midland MI
Robert J. Broersma - Midland MI
George D. Dickerson - Midland MI
Assignee:
The Dow Chemical Company - Midland MI
International Classification:
A61K 31135
A61K 3133
A61K 31535
A61K 31445
US Classification:
424330
Abstract:
A method for inhibiting blood platelet aggregation in a mammal by administering internally to the mammal an effective amount of a phenylthio(sulfinyl or sulfonyl)alkylamine compound or a pharmaceutically-acceptable salt thereof.

Method For Inhibiting Adp-Induced Platelet Aggregation Using Phenylthioalkylamines

US Patent:
4155907, May 22, 1979
Filed:
Aug 16, 1976
Appl. No.:
5/714950
Inventors:
Joseph E. Dunbar - Midland MI
Louis E. Begin - Midland MI
Robert J. Broersma - Midland MI
George D. Dickerson - Midland MI
Assignee:
The Dow Chemical Company - Midland MI
International Classification:
A61K 31535
A61K 3122
A61K 31195
A61K 31165
US Classification:
4242485
Abstract:
A method for inhibiting blood platelet aggregation in a mammal by administering internally to the mammal an effective amount of a phenylthio(sulfinyl or sulfonyl)alkylamine compound or a pharmaceutically-acceptable salt thereof.

Method For Inhibiting Adp-Induced Platelet Aggregation Using Phenylthioalkylamines

US Patent:
4141983, Feb 27, 1979
Filed:
Sep 14, 1977
Appl. No.:
5/833124
Inventors:
Joseph E. Dunbar - Midland MI
Louis E. Begin - Midland MI
Robert J. Broesma - Midland MI
George D. Dickerson - Midland MI
Assignee:
The Dow Chemical Company - Midland MI
International Classification:
A61K 31445
US Classification:
424267
Abstract:
A method for inhibiting blood platelet aggregation in a mammal by administering internally to the mammal an effective amount of a phenylthio(sulfinyl or sulfonyl)alkylamine compound or a pharmaceutically-acceptable salt thereof.

Morpholinoalkylthiopyridazine Compounds

US Patent:
4087605, May 2, 1978
Filed:
Jul 22, 1977
Appl. No.:
5/817936
Inventors:
Joseph E. Dunbar - Midland MI
Louis E. Begin - Midland MI
Assignee:
The Dow Chemical Company - Midland MI
International Classification:
C07D41306
US Classification:
544114
Abstract:
This invention concerns novel aminoalkylthiopyridazine compounds useful for inhibiting the aggregation of blood platelets in animals and a process for preparing the compounds from an isothiuronium salt generated in situ from an aminoalkyl halide and thiourea. The compounds also have fungicidal and nematocidal properties.

Aminoalkylsulfides, Aminoalkylsulfoxides, And Aminoalkylsulfones

US Patent:
4281118, Jul 28, 1981
Filed:
Jun 18, 1979
Appl. No.:
6/049029
Inventors:
Joseph E. Dunbar - Midland MI
Louis E. Begin - Midland MI
Assignee:
The Dow Chemical Company - Midland MI
International Classification:
C07D41312
C07D29508
A61K 31535
A61K 31445
US Classification:
544 85
Abstract:
Novel aminoalkylsulfides, aminoalkylsulfoxides and aminoalkylsulfones of the general formula ##STR1## wherein y and z independently represent the integer 0, 1 or 2; a represents the integer 0 or 2; n represents the integer 1, 2, 3 or 4; R. sub. 1 independently represent lower alkyl or hydrogen or alternatively R. sub. 1 and R. sub. 2 taken together with the adjacent nitrogen atom represent a 5 or 6 membered heterocyclic ring which may optionally contain an oxygen atom whereby a morpholino, piperidino, or pyrrolidino grouping is formed; R. sub. 3 represents halo such as chloro or bromo, lower alkylthio, arloweralkylthio, arylthio such as 4-methylphenylthio, 4-morpholinylloweralkylthio such as 4-morpholinylpropylthio, lower alkyl or arloweralkylamino such as 4-methoxybenzenemethanamino; R. sub. 4 represents hydrogen or lower alkyl. The invention also includes the pharmaceutically-acceptable salts of the compounds described herein.

Antithrombotic 1,3,4-Thiadiazole

US Patent:
4074049, Feb 14, 1978
Filed:
Nov 19, 1976
Appl. No.:
5/743200
Inventors:
Louis E. Begin - Midland MI
Joseph E. Dunbar - Midland MI
Assignee:
The Dow Chemical Company - Midland MI
International Classification:
C07D4134
US Classification:
544 82
Abstract:
A series of 1,3,4-thiadiazoles substituted in the 2,5-position with amino, dialkylaminoalkylthio, or heterocyclicalkylthio are useful as antithrombotic agents.

Aminoalkylthiopurines

US Patent:
4189579, Feb 19, 1980
Filed:
Nov 20, 1978
Appl. No.:
5/962525
Inventors:
Joseph E. Dunbar - Midland MI
Louis E. Begin - Midland MI
Assignee:
The Dow Chemical Company - Midland MI
International Classification:
C07D47338
US Classification:
544276
Abstract:
Novel aminoalkyl purine and pyrazolopyrimidine compounds useful in the inhibition of blood platelet aggregation in animals.

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