Mark T W Hsieh, Age 87Philadelphia, PA

Mark Hsieh Phones & Addresses

Philadelphia, PA

Palm Bay, FL

1001 Sharpless Rd, Elkins Park, PA 19027 (215) 635-1904

1101 Valley Glen Rd, Elkins Park, PA 19027

Melrose Park, PA

1001 Sharpless Rd, Elkins Park, PA 19027

Mentions for Mark T W Hsieh

Career records & work history

License Records

Mark Hsieh

Licenses:
License #: E054960 - Expired
Category: Emergency medical services
Issued Date: Nov 23, 2009
Expiration Date: Mar 31, 2010
Type: Los Angeles County EMS Agency

Resumes & CV records

Resumes

Mark Hsieh Photo 37

Mark Hsieh

Mark Hsieh Photo 38

Ww Services Sales Excellence At Microsoft

Position:
MACH MBA Services Project Manager at Microsoft, Founder at LYVE Products
Location:
Redmond, Washington
Industry:
Information Technology and Services
Work:
Microsoft - Beijing since May 2012
MACH MBA Services Project Manager
LYVE Products since Jan 2011
Founder
Efficient Lighting Jan 2010 - Jan 2012
Director of Sales
Aramark Uniform Services Oct 2007 - Jan 2010
Account Executive
Aramark Uniform Services May 2007 - Sep 2007
Sales Representative
Benchmark Mortgage Jul 2006 - May 2007
Loan Officer
United States Marine Corps Jan 2002 - Dec 2002
Lance Corporal
Education:
University of Southern California - Marshall School of Business 2009 - 2011
MBA, Entrepreneurship
University of California, Los Angeles 2002 - 2006
BS, Cognitive Science
Skills:
New Business Development, Contract Negotiations, Customer Acquisition, Retail, Research, Manufacturing, Sales Management, CRM software, Marketing Strategy, Business Strategy, Business Management, Business Development, Contract Negotiation, Account Management, Start-ups, Strategy, Team Leadership, Product Management, Cross-functional Team Leadership, Sales Presentations, Sales, Product Marketing, Team Building, E-commerce, Coaching, Competitive Analysis, Product Development, Management, Entrepreneurship, Strategic Planning, B2B, CRM, Leadership, Team Management
Interests:
Golf
Honor & Awards:
National Defense Medal (USMC)
Languages:
English
Chinese
Taiwanese
Mark Hsieh Photo 39

Mark Hsieh

Location:
Cambridge, United Kingdom
Industry:
Information Technology and Services

Publications & IP owners

Us Patents

Anti-Cd26 Antibodies And Methods Of Use Thereof

US Patent:
7462698, Dec 9, 2008
Filed:
Jul 24, 2006
Appl. No.:
11/492498
Inventors:
Teikichi Aoyagi - Saitama, JP
Peter Peizhi Luo - Lansdale PA, US
Pingyu Zhong - Blue Bell PA, US
Mark Hsieh - Jenkintown PA, US
Yan Li - Sunnyvale CA, US
Kevin Caili Wang - San Francisco CA, US
Chikao Morimoto - Setagaya-ku, JP
Assignee:
Y's Therapeutics Co., Ltd. - Tokyo
International Classification:
C12P 21/08
C07K 16/00
A61K 35/395
A61K 39/00
US Classification:
5303873, 5303871, 4241301, 4241331, 4241581, 4241721
Abstract:
The present invention provides novel anti-CD26 antibodies and other, related polypeptides, as well as novel polynucleotides encoding the antibodies and polypeptides. The invention also provides methods of making the antibodies and polypeptides. Compositions and cells comprising the antibodies or polypeptides are further provided. Methods of using the antibodies and/or polypeptides, such as to inhibit cell proliferation and in the treatment of conditions associated with CD26, are also provided.

Anti-Cd26 Antibodies And Methods Of Use Thereof

US Patent:
8030469, Oct 4, 2011
Filed:
Nov 3, 2008
Appl. No.:
12/263919
Inventors:
Teikichi Aoyagi - Saitama, JP
Peter Peizhi Luo - Lansdale PA, US
Pingyu Zhong - Blue Bell PA, US
Mark Hsieh - Jenkintown PA, US
Yan Li - San Jose CA, US
Kevin Caili Wang - Lansdale PA, US
Chikao Morimoto - Setagaya-ku, JP
Assignee:
SBI Incubation Co., Ltd. - Tokyo
International Classification:
C07H 21/02
C07H 21/04
A61K 39/395
A61K 39/00
US Classification:
536 2353, 536 231, 4241301, 4241331, 4241581, 4241721
Abstract:
The present invention provides novel anti-CD26 antibodies and other, related polypeptides, as well as novel polynucleotides encoding the antibodies and polypeptides. The invention also provides methods of making the antibodies and polypeptides. Compositions and cells comprising the antibodies or polypeptides are further provided. Methods of using the antibodies and/or polypeptides, such as to inhibit cell proliferation and in the treatment of conditions associated with CD26, are also provided.

Generation And Affinity Maturation Of Antibody Library In Silico

US Patent:
2011012, May 26, 2011
Filed:
Oct 29, 2010
Appl. No.:
12/916077
Inventors:
Peizhi Luo - Lansdale PA, US
Mark Hsieh - San Mateo CA, US
Pingyu Zhong - Blue Bell PA, US
Caili Wang - San Francisco CA, US
Yicheng Cao - Sunnyvale CA, US
Shengjiang Liu - Mountain View CA, US
International Classification:
C40B 50/02
US Classification:
506 24
Abstract:
The present invention provides a methodology for efficiently generating and screening protein libraries for optimized proteins with desirable biological functions, such as improved binding affinity towards biologically and/or therapeutically important target molecules. The process is carried out computationally in a high throughput manner by mining the ever-expanding databases of protein sequences of all organisms, especially human. In one embodiment, a method for constructing a library of designed proteins, comprising the steps of: providing an amino acid sequence derived from a lead protein, the amino acid sequence being designated as a lead sequence; comparing the lead sequence with a plurality of tester protein sequences; and selecting from the plurality of tester protein sequences at least two peptide segments that have at least 15% sequence identity with the lead sequence, the selected peptide segments forming a hit library; and forming a library of designed proteins by substituting the lead sequence with the hit library. The library of designed proteins can be expressed in vitro or in vivo to produce a library of recombinant proteins that can be screened for novel or improved function(s) over the lead protein, such as an antibody against therapeutically important target.

Structure-Based Selection And Affinity Maturation Of Antibody Library

US Patent:
2012012, May 24, 2012
Filed:
Oct 28, 2010
Appl. No.:
12/914105
Inventors:
Peizhi Luo - Lansdale PA, US
Mark Hsieh - San Mateo CA, US
Pingyu Zhong - Blue Bell PA, US
Caili Wang - San Francisco CA, US
International Classification:
C40B 10/00
US Classification:
506 1
Abstract:
The present invention provides a structure-based methodology for efficiently generating and screening a library of recombinant antibodies for optimized antibodies with desirable functions, such as higher binding affinity or low immunogenicity. In one embodiment, a method is provided for constructing a library of antibody sequences based on a three dimensional structure of a lead antibody. The method comprises: providing a lead structural template comprising the amino acid sequence of the variable region of the heavy chain (V) or light chain (V) of a lead antibody, comparing the lead template sequence with a plurality of tester protein sequences; selecting a hit library from the tester protein sequences; determining if a member of the hit library is structurally compatible with the lead structural template using a scoring function; selecting members for the hit library that score equal to or better than the lead sequence and screening members for improved function(s).

Ax213 And Ax132 Psck9 Antagonists And Variants

US Patent:
2012021, Aug 23, 2012
Filed:
Oct 29, 2010
Appl. No.:
13/503729
Inventors:
Peter Peizhi Luo - Lansdale PA, US
Pingyu Zhong - Blue Bell PA, US
Mark Hsieh - Jenkintown PA, US
Yan Li - San Jose CA, US
Xinwei Wang - Germantown MD, US
Feng Dong - Lansdale PA, US
Andrei Golosov - Cambridge MA, US
Yan Ni - Westfield NJ, US
Weirong Wang - Harleysville PA, US
Laurence B. Peterson - Westfield NJ, US
Rose Cubbon - Fanwood NJ, US
Sujata Sharma - Eagleville PA, US
Jon Condra - Doylestown PA, US
Jun Lu - Lansdale PA, US
Gopalakrishnan Parthasarathy - Hillsborough NJ, US
Stephen Soisson - Hillsborough NJ, US
Noel Byrne - Doylestown PA, US
International Classification:
A61K 39/395
C12N 15/13
C12P 21/02
A61P 3/06
C12N 5/10
C12N 1/19
C12N 1/21
C07K 16/40
C12N 15/63
US Classification:
4241461, 53038826, 536 2353, 435 696, 4353201, 435338, 43525423, 435419, 43525233, 43525231, 43525235
Abstract:
Antagonists of human proprotein convertase subtilisin-kexin type 9 (“PCSK9”) are disclosed. The disclosed antagonists are effective in the inhibition of PCSK9 function and, accordingly, present desirable antagonists for use in the treatment of conditions associated with PCSK9 activity. The present invention also discloses nucleic acid encoding said antagonists, vectors, host cells, and compositions comprising the antagonists. Methods of making PCSK9-specific antagonists as well as methods of using the antagonists for inhibiting or antagonizing PCSK9 function are also disclosed and form important additional aspects of the present disclosure.

Public records

Vehicle Records

Mark Hsieh

Address:
1001 Sharpless Rd, Melrose Park, PA 19027
Phone:
(215) 635-1904
VIN:
4S3BMBJ65C3011297
Make:
SUBARU
Model:
LEGACY
Year:
2012

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