Mark A Krasnow, Age 67801 San Francisco Ct, Palo Alto, CA 94305

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801 San Francisco Ct, Stanford, CA 94305 (650) 494-1314

Palo Alto, CA

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Position: Professional/Technical

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Degree: Graduate or professional degree

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Us Patents

Sprouty Protein And Coding Sequence

US Patent:
6060275, May 9, 2000
Filed:
Nov 7, 1997
Appl. No.:
8/965903
Inventors:
Nir Hacohen - Cambridge MA
Mark A. Krasnow - Stanford CA
Assignee:
The Board of Trustees of the Leland Standord Junior University - Stanford CA
International Classification:
C12N 510
C12N 1512
C12N 1579
C12P 2102
US Classification:
435 691
Abstract:
A new class of mammalian sprouty proteins is disclosed. The proteins are characterized by an amino acid sequence whose cysteine-rich region has at least 40% sequence identity with SEQ ID NO:17 in the human sprouty 2 protein whose full length sequence is identified by SEQ ID NO:8. Also disclosed are (i) a pharmaceutical preparation containing a sprouty protein, (ii) a DNA sequence encoding the protein, (iii) vector and gene therapy compositions containing the DNA coding sequence, and (iv) methods of detecting a condition characterized by, or risk factor associated with, abnormal levels of active mammalian sprouty protein in a mammalian subject.

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