Melissa A Kacena, Age 516584 Regents Park Dr, Zionsville, IN 46077
Melissa Kacena Phones & Addresses
6584 Regents Park Dr, Zionsville, IN 46077
Rockville, IN
Brighton, MA
110 Bishop St, New Haven, CT 06511
Barrington, RI
Littleton, CO
Brookline, MA
Work
Position:
Professional/Technical
Education
Degree:
High school graduate or higher
Mentions for Melissa A Kacena
Publications & IP owners
Us Patents
Composition And Method For Maintenance, Differentiation, And Proliferation Of Stem Cells
US Patent:
2012011, May 10, 2012
Filed:
Jul 16, 2010
Appl. No.:
13/383796
Inventors:
Edward F. Srour - Indianapolis IN, US
Melissa A. Kacena - Zionsville IN, US
Melissa A. Kacena - Zionsville IN, US
Assignee:
PURDUE RESEARCH FOUNDATION - West Lafayette IN
International Classification:
C12N 5/077
C12N 5/02
C12N 5/07
C12N 5/02
C12N 5/07
US Classification:
435347, 435325, 435373, 435375
Abstract:
Compositions and methods for the proliferation, differentiation, and maintenance of stem cells are described. Preferred are the use of hematopoietic stem cells in combination with a collagen matrix.
Use Of Compounds With Thrombopoietic Activity To Promote Bone Growth And Healing
US Patent:
2013014, Jun 13, 2013
Filed:
Jun 3, 2011
Appl. No.:
13/700904
Inventors:
Melissa A. Kacena - Zionsville IN, US
Tien-Min Gabriel Chu - Carmel IN, US
Tien-Min Gabriel Chu - Carmel IN, US
Assignee:
INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION - INDIANAPOLIS
International Classification:
A61L 27/54
US Classification:
424400, 514 78, 4241341, 435375
Abstract:
TPO was used to promote the growth of bone in both rats and in mice. Gaps in both mouse and in rat bones were treated with a scaffold sized to fit the gap. Scaffolds that included TPO promoted better outcomes than scaffolds that included BMP-2 or scaffolds that did not include either TPO or BMP-2. These data indicate that compounds that exhibit thrombopoietic activity such a recombinant TPO can be used to promote bone growth and healing in mammals.
Materials And Methods For Treating Critically Sized Defects In Mouse Bone
US Patent:
2011028, Nov 24, 2011
Filed:
May 20, 2011
Appl. No.:
13/112820
Inventors:
Melissa A. Kacena - Zionsville IN, US
Tien-Min Gabriel Chu - Carmel IN, US
Daniel Alge - Longmont CO, US
Tien-Min Gabriel Chu - Carmel IN, US
Daniel Alge - Longmont CO, US
Assignee:
Indiana University Research & Technology Corporation - Indianapolis IN
International Classification:
A61F 2/28
US Classification:
623 2361
Abstract:
Scaffolds equipped to include biologically active reagents such as proteins sized and engineered specifically for use in a mouse were made and implanted into mice. The scaffold was specifically designed for use in a mouse femoral critical sized defect Scaffolds. Special care was taken when casting these scaffolds to ensure that the material used to form the body of the scaffold did not include defects such as a large number of macroscopic holes that could compromise the structural integrity of these very small devices. Some of these scaffolds include a hollow center that accommodate a rod that ran the longitudinal length of the scaffold extending into the adjacent bone to anchor the scaffold to the bone. Scaffold also include at least one channel that extended from the outside of the structure towards its center and could be hold a liquid or paste comprising for example exogenous BMP-2.
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