Milan N Stojanovic, Age 58366 Franklin Ave, Ridgewood, NJ 07450

7381531, Jun 3, 2008

May 6, 2005

11/123648

Milan N. Stojanovic - Fort Lee NJ, US
Donald W. Landry - New York NY, US

The Trustees of Columbia University in the City of New York - New York NY

C12Q 1/68

435 6

Complex of an anti-cocaine aptamer and the dye diethylthiotricarbocyanine behaves as a calorimetric sensor with attenuation in absorbance at 760 nm for cocaine in the concentration range of 2-5000 μM. Mechanistic studies indicate an intermolecular displacement of the dye as the mechanism of action of the sensor. As the dye is insoluble in buffer, cocaine binding can be detected as displaced dye precipitates and supernatant decolorizes.

7470516, Dec 30, 2008

Oct 14, 2005

11/251496

Milan N. Stojanovic - Fort Lee NJ, US
Donald Landry - New York NY, US
Dragan B. Nikic - Belgrade, YU

The Trustees of Columbia University in the City of New York - New York NY

C12Q 1/68
C12P 19/34
C07H 21/02
C07H 21/00

435 6, 435 911, 536 231, 536 2532

This invention provides analyte sensitive oligonucleotide compositions for detecting and analyzing analytes in solution, including complex solutions using cross reactive arrays of analyte sensitive oligonucleotide compositions.

7550619, Jun 23, 2009

Dec 19, 2005

11/311598

Yadagiri R. Pendri - South Glastonbury CT, US
Chung-Pin H. Chen - Madison CT, US
Jing Liang - Princeton NJ, US
Shaopeng Wang - King of Prussia PA, US
Milan Stojanovic - Fort Lee NJ, US
Richard P. Polniaszek - Redwood City CA, US
John Thottathil - Ivanhoe IL, US

Bristol-Myers Squibb Company - Princeton NJ

C07F 7/04
C07F 7/08

556441, 556436, 556473, 556465, 556413, 556443, 556482, 556489, 562126, 568660

Intermediates useful in the preparation of the antiviral agent entecavir are disclosed. A resin adsorption process for the isolation and purification of entecavir is also disclosed. Various processes useful in the preparation of entecavir are also disclosed.

8084204, Dec 27, 2011

Apr 24, 2008

12/148999

Milan N. Stojanovic - Fort Lee NJ, US
Donald W. Landry - New York NY, US

The Trustees of Columbia University in the City of New York - New York NY

C12Q 1/68

435 61

Complex of an anti-cocaine aptamer and the dye diethylthiotricarbocyanine behaves as a calorimetric sensor with attenuation in absorbance at 760 nm for cocaine in the concentration range of 2-5000 μM. Mechanistic studies indicate an intermolecular displacement of the dye as the mechanism of action of the sensor. As the dye is insoluble in buffer, cocaine binding can be detected as displaced dye precipitates and supernatant decolorizes.

8119782, Feb 21, 2012

Jan 12, 2009

12/319835

Joanne MacDonald - New York NY, US
Milan N. Stojanovic - Fort Lee NJ, US
Darko Stefanovic - Albuquerque NM, US

The Trustees of Columbia University in the City of New York - New York NY

C07H 21/04

536 231

The development of the first solution-phase molecular assembly comprising over 100 molecular logic gates, which more than quadruples the complexity performed by any previous system. “MAYA-II” is a second generation molecular automaton capable of playing a complete game of tic-tac-toe against a human opponent, and encompasses 76 permissible game plays. MAYA-II is more user-friendly than MAYA-I, as it signals both players move in a two-color output system and imposes no constraints on the position of the human player's first move. MAYA-II is constructed from three classes of stem-loop controlled deoxyribozyme-based logic gates that are allosterically modulated by input oligonucleotides to produce fluorescent output signals.

2003019, Oct 23, 2003

Apr 19, 2002

10/126727

Milan Stojanovic - Fort Lee NJ, US
Donald Landry - New York NY, US

C12Q001/68
C12M001/34

435/006000, 435/287200

Complex of an anti-cocaine aptamer and the dye diethylthiotricarbocyanine behaves as a colorimetric sensor with attenuation in absorbance at 760 nm for cocaine in the concentration range of 2-5000 M. Mechanistic studies indicate an intermolecular displacement of the dye as the mechanism of action of the sensor. As the dye is insoluble in buffer, cocaine binding can be detected as displaced dye precipitates and supernatant decolorizes.

2004000, Jan 8, 2004

Jul 3, 2002

10/189103

Milan Stojanovic - Fort Lee NJ, US

C12Q001/68
C07H021/04

435/006000, 536/023100

A macromolecular assembly has a body and at least four catalytic leg units having nucleic acids and is adapted to travel across a layer of oligonucleotide fuel substrate molecules by having each leg unit recognize and bind to a fuel substrate, cleave the fuel substrate and search for a new fuel substrate, said leg units alternately binding and cleaving out of phase to keep at least one leg unit bound to a fuel substrate. The fuel molecules may be arranged to provide a gradient, whereby the assembly travels along the gradient.

2004007, Apr 15, 2004

Feb 21, 2003

10/371550

Milan Stojanovic - Fort Lee NJ, US

H03K019/00

326/136000

A set of deoxyribozyme-based logic gates are capable of generating any Boolean function. The gates include basic NOT and AND gates, and the more complex XOR gate. These gates were constructed through modular design that combines molecular beacon stem-loops with hammerhead-type deoxyribozymes. The gates have oligonucleotides as both inputs and output, thereby communication between various computation elements in solution. The operation of these gates is conveniently connected to a fluorescent readout.