Pierre J Mallorga, Age 72272 Country Club Dr, Telford, PA 18969

Pierre Mallorga Phones & Addresses

272 Country Club Dr, Telford, PA 18969 (215) 723-4646

Montgomery, PA

304 Abbey Ln, Lansdale, PA 19446 (215) 362-6349

Sun City West, AZ

Lower Gwynedd, PA

304 Abbey Ln, Lansdale, PA 19446

Social networks

Pierre J Mallorga

Linkedin

Work

Company: Merck Position: Retired

Industries

Pharmaceuticals

Mentions for Pierre J Mallorga

Resumes and CV

Resumes

Pierre Mallorga Photo 1

Pierre Mallorga

Location:
Telford, PA
Industry:
Pharmaceuticals
Work:
Merck
Retired

Publications

Us Patents

Treatment Of Psychosis With A Muscarinic M1 Receptor Ectopic Activator

US Patent:
2006023, Oct 19, 2006
Filed:
Feb 17, 2004
Appl. No.:
10/545767
Inventors:
P. Conn - Brentwood TN, US
Marlene Jacobson - Melrose Park PA, US
Pierre Mallorga - Lansdale PA, US
Edward Scolnick - Wynniwood PA, US
Cyrille Sur - Harleysville PA, US
International Classification:
A61K 31/5415
A61K 31/4439
A61K 31/4745
A61K 9/00
US Classification:
424400000, 514225800, 514283000
Abstract:
A muscarinic M1 receptor ectopic activator, such as a muscarinic M1 receptor allosteric potentiator or a muscarinic M1 receptor ectopic agonist is useful, alone or in combination with other antipsychotic agents, for treating or preventing psychosis, such as a schizophrenic disorder or psychosis in Alzheimer's disease or bipolar disorder, for enhancing cognition and for neuropathic pain.

Muscarine Antagonists

US Patent:
5574044, Nov 12, 1996
Filed:
Oct 27, 1994
Appl. No.:
8/329757
Inventors:
Wayne J. Thompson - Lansdale PA
Michael F. Sugrue - Blue Bell PA
Richard W. Ransom - New Britian PA
Pierre J. Mallorga - Lansdale PA
Ian M. Bell - North Wales PA
Anthony M. Smith - Green Lane PA
Assignee:
Merck & Co., Inc. - Rahway NJ
International Classification:
A61K 31445
C07D40114
US Classification:
514316
Abstract:
Compounds, 1,3-dihydro-1-{1-[piperidin-4-yl]piperidin-4-yl}-2H-benzimidazol-2-ones and 1,3-dihydro-1-{4-amino-1-cyclohexyl}-2H-benzimidazol-2-ones and derivatives thereof, their preparation, method of use and pharmaceutical compositions are described. These compounds are endowed with antimuscarinic activity and are useful in the treatment and/or prevention of myopia (commonly known as nearsightedness).

Muscarine Agonists

US Patent:
5718912, Feb 17, 1998
Filed:
Oct 28, 1996
Appl. No.:
8/736705
Inventors:
Wayne J. Thomspon - Lansdale PA
Pierre Mallorga - Lansdale PA
Richard W. Ransom - New Britain PA
Ian M. Bell - Harleysville PA
Michael F. Sugrue - Blue Bell PA
Peter M. Munson - Harleysville PA
Assignee:
Merck & Co., Inc. - Rahway NJ
International Classification:
A61F 200
A01N 4340
A61K 31445
US Classification:
424427
Abstract:
This invention is concerned with novel 1-›cycloalkylpioeridin-4-yl!-2H benzimidazolones, their compositions and method of use. The novel compounds are selective muscarinic agonists of the m2 subtype with low activity at the m3 subtype. The compounds are effective for the treatment of glaucoma with fewer side effects than the pilocarpine therapy.

Muscarine Antagonists

US Patent:
5691323, Nov 25, 1997
Filed:
May 12, 1995
Appl. No.:
8/440153
Inventors:
Wayne J. Thompson - Lansdale PA
Michael F. Sugrue - Blue Bell PA
Richard W. Ransom - New Britian PA
Pierre J. Mallorga - Lansdale PA
Ian M. Bell - Harleysville PA
Anthony M. Smith - Green Lane PA
Assignee:
Merck & Co., Inc. - Rahway NJ
International Classification:
A61K 3138
A61K 3134
C07D40314
C07D40312
US Classification:
514 94
Abstract:
Compounds, 1,3-dihydro-1-{1-›piperidin-4-yl!piperidin-4-yl}-2H-benzimidazol-2-ones and 1,3-dihydro-1-{4-amino-1-cyclohexyl}-2H-benzimidazol-2-ones and derivatives thereof, their preparation, method of use and pharmaceutical compositions are described. These compounds are endowed with antimuscarinic activity and are useful in the treatment and/or prevention of myopia (commonly known as nearsightedness).

Muscarine Antagonists

US Patent:
5756508, May 26, 1998
Filed:
Oct 28, 1996
Appl. No.:
8/736704
Inventors:
Wayne J. Thompson - Lansdale PA
Richard W. Ransom - New Britain PA
Pierre Mallorga - Lansdale PA
Michael F. Sugrue - Blue Bell PA
Assignee:
Merck & Co., Inc. - Rahway NJ
International Classification:
C07D21114
C07D23526
C07D23926
A61K 31415
US Classification:
514256
Abstract:
This invention is concerned with novel 1,3-dihydro-1-›1-(1-heteroarylpiperidin-4-yl)piperidin-4-yl!-2H-benzimidaz olones, derivatives thereof, their preparation, method of use and pharmaceutical compositions. These compounds are endowed with antimuscarinic activity and are useful in the treatment and/or prevention of myopia (commonly known as nearsightedness).

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