Richard J Deckelbaum, Age 828 Harvard Ave, Yonkers, NY 10706

8633253, Jan 21, 2014

Jul 29, 2013

13/953718

Richard J. Deckelbaum - Hastings on Hudson NY, US
Yvon Carpentier - Brussels, BE

The Trustees of Columbia University in the City of New York - New York NY

B01F 3/00

516 9

The present invention relates to omega-3 diglyceride emulsions characterized in that the lipid phase comprises at least about 40 wt. -% of diglycerides. Preferably about 70 wt. -% of the acyl-groups of said diglycerides, are eicoapentaenoic acid (EPA) groups and/or docasahexaenoic (DHA) groups. The invention further relates to methods of treatment using the omega-3 diglyceride emulsions.

2013017, Jul 11, 2013

Mar 4, 2013

13/783779

Richard J. DECKELBAUM - Hastings on Hudson NY, US
Yvon CARPENTIER - Brussels, BE

The Trustees of Columbia University in The City of New York - New York NY

A61K 31/231

514547

The present invention relates to omega-3 diglyceride emulsions characterized in that the lipid phase comprises at least about 40 wt.-% of diglycerides. Preferably about 70 wt.-% of the acyl-groups of said diglycerides, are eicoapentaenoic acid (EPA) groups and/or docasahexaenoic (DHA) groups. The invention further relates to methods of treatment using the omega-3 diglyceride emulsions.

2015027, Oct 1, 2015

Jun 12, 2015

14/738822

Richard J. Deckelbaum - Hastings on Hudson NY, US
Susan J. Vannucci - New York NY, US

The Trustees of Columbia University in the City of New York - New York NY

A61K 31/232
A61K 31/202
A61K 35/60
A61K 9/107

The present invention provides methods of limiting cell death resulting from hypoxic-ischemia comprising, administering an omega-3 lipid-based emulsion after a hypoxic-ischemia insult. The omega-3 lipid-based emulsion preferably comprises at least 20% omega-3 oil, by weight, and wherein the omega-3 oil comprises at least 20% omega-3 triglycerides and/or diglycerides, and wherein fatty acids of the omega-3 trigylceride and/or diglycerides comprise at least 40% EPA and/or DHA. The present invention also provides novel fish-oil compositions for administration after an ischemic insult to limit cell death in the organ that underwent an ischemic event.

2014028, Sep 25, 2014

Jun 9, 2014

14/299440

Richard J. Deckelbaum - Hastings on Hudson NY, US

The Trustees of Columbia University in the City of New York - New York NY

A61K 31/202
A61K 9/107

424400, 514560, 424523

The present invention provides methods of limiting cell death or damage or reperfusion damage resulting from hypoxic-ischemia, comprising administering an omega-3 triglyceride emulsion after a hypoxic-ischemia insult. The omega-3 triglyceride emulsion preferably comprises from about 7% to 35% omega-3 oil by weight in grams per 100 ml of emulsion; the omega-3 oil comprises about 20% to 100% triglyceride by weight per total weight of the omega-3 oil and about 20% wt.-% to 100% of the acyl-groups of the omega-3 triglycerides consist of DHA; the omega-3 oil comprises less than 10% omega-6 fatty acids; and the mean diameter of lipid droplets in the emulsion is less than about 5 microns.

2014009, Apr 10, 2014

Dec 10, 2013

14/102146

Richard J. Deckelbaum - Hastings on Hudson NY, US
Yvon Carpentier - Brussels, BE

The Trustees of Columbia University in the City of New York - New York NY

A61K 31/231

424400, 514547

The present invention relates to omega-3 diglyceride emulsions characterized in that the lipid phase comprises at least about 40 wt.-% of diglycerides. Preferably about 70 wt.-% of the acyl-groups of said diglycerides are eicoapentaenoic acid (EPA) groups and/or docasahexaenoic (DHA) groups. The invention further relates to methods of treatment using the omega-3 diglyceride emulsions.

2012009, Apr 19, 2012

Dec 23, 2011

13/336290

Richard J. DECKELBAUM - Hastings-on-Hudson NY, US
Susan J. VANNUCCI - New York NY, US

The Trustees of Columbia University in the City of New York - New York NY

A61K 31/232
A61P 9/10
A61P 29/00
A61P 25/00

514547

The present invention provides methods of limiting cell death resulting from hypoxic-ischemia comprising, administering an omega-3 lipid-based emulsion after a hypoxic-ischemia insult. The omega-3 lipid-based emulsion preferably comprises at least 20% omega-3 oil, by weight, and wherein the omega-3 oil comprises at least 20% omega-3 triglycerides and/or diglycerides, and wherein fatty acids of the omega-3 trigylceride and/or diglycerides comprise at least 40% EPA and/or DHA. The present invention also provides novel fish-oil compositions for administration after an ischemic insult to limit cell death in the organ that underwent an ischemic event.

2010009, Apr 15, 2010

Sep 19, 2007

12/441795

Richard J. Deckelbaum - Hastings-on-Hudson NY, US
Yvon Carpentier - Brussels, BE

A61K 31/225
A61P 43/00

514547

The present invention relates to omega- diglyceride emulsions characterized in that the lipid phase comprises at least about 40 wt.-% of diglycerides. Preferably about 70 wt. -% of the acyl-groups of said diglycerides, are eicosapentaenoic acid (EPA) groups and/or docosahexaenoic (DHA) groups. The invention further relates to methods of treatment using the omega-3 diglyceride emulsions.

2005000, Jan 13, 2005

Jul 27, 2004

10/900626

Richard Deckelbaum - Hastings-on-Hudson NY, US
Yvon Carpentier - Brussels, BE

A61K009/00
A61K031/205
A61K047/00

424400000, 514786000

This invention provides compositions in the form of emulsions comprising pharmaceutical agents, triglycerides and emulsifiers. This invention also provides methods for delivering pharmaceutical agents to predetermined tissues comprising administering the instant compositions. This invention also provides methods of making the instant compositions.