Richard H KreamNorwood, MA

Richard Kream Phones & Addresses

Norwood, MA

Work

Address: 536 Broad Street Suite 5 Post Office Box 890117, East Weymouth, MA 02189

Ranks

Licence: Massachusetts - Active Date: 1972

Mentions for Richard H Kream

Career records & work history

Lawyers & Attorneys

Richard Kream Photo 1

Richard H. Kream, East Weymouth MA - Lawyer

Address:
536 Broad Street Suite 5 Post Office Box 890117, East Weymouth, MA 02189
(781) 331-9333 (Office)
Licenses:
Massachusetts - Active 1972
Richard Kream Photo 2

Richard H. Kream, Weymouth MA - Lawyer

Office:
Kream & Kream
536 Broad St., Suite 5, P.o. Box 117, Weymouth, MA
Specialties:
Collections, Estates Law, Trusts Law
ISLN:
905740537
Admitted:
1972
University:
University of Pittsburgh, B.A.
Law School:
New England School of Law, J.D.

Publications & IP owners

Us Patents

Chimeric Analgesic Peptides

US Patent:
6759520, Jul 6, 2004
Filed:
Oct 28, 1999
Appl. No.:
09/428692
Inventors:
Daniel B. Carr - Chestnut Hill MA
Andrzej W. Lipkowski - Warsaw, PL
Richard Kream - Roslindale MA
Aleksandra Misicka-Kesik - Piastow, PL
Assignee:
The New England Medical Center Hospitals, Inc. - Boston MA
International Classification:
C07K 100
US Classification:
530402, 530300, 514 2
Abstract:
The present invention provides a novel chimeric peptide containing an opioid peptide moiety and a nociceptive peptide moiety for producing analgesia.

Novel Chimeric Analgesic Peptides

US Patent:
2006010, May 18, 2006
Filed:
Apr 21, 2004
Appl. No.:
10/828623
Inventors:
Daniel Carr - Chestnut Hill MA, US
Andrzej Lipkowski - Warsaw, PL
Richard Kream - Roslindale MA, US
Aleksandra Misicka-Kesik - Piastow, PL
International Classification:
C07K 14/675
A61K 38/22
US Classification:
514012000, 530399000
Abstract:
The present invention provides a novel chimeric peptide containing an opioid peptide moiety and a nociceptive peptide moiety for producing analgesia

Novel Chimeric Analgesic Peptides

US Patent:
2009029, Dec 3, 2009
Filed:
Mar 28, 2007
Appl. No.:
11/692872
Inventors:
Daniel B. Carr - Chestnut Hill MA, US
Andrzej W. Lipkowski - Warsaw, PL
Richard Kream - Roslindale MA, US
Aleksandra Misicka-Kesik - Piastow, PL
International Classification:
A61K 38/17
A61K 38/02
A61K 38/08
A61K 38/07
A61P 25/00
US Classification:
514 12, 514 2, 514 18, 514 16
Abstract:
The present invention provides a novel chimeric peptide containing an opioid peptide moiety and a nociceptive peptide moiety for producing analgesia.

Methodology For Eliciting An Analgesic Response In A Living Subject

US Patent:
5891842, Apr 6, 1999
Filed:
Apr 12, 1996
Appl. No.:
8/631434
Inventors:
Richard M. Kream - Wollaston MA
Assignee:
Trustees of Tufts College - Medford MA
International Classification:
A61K 3804
US Classification:
514 2
Abstract:
The present invention provides a method for eliciting an opioidal analgesia in a living subject using two classes of chemical compositions previously thought to have directly contradictory and physiologically antagonistic roles in the spinal analgesic process. The present methodology relies upon a concurrent administration of an opioid in marginal concentrations in combination with marginal doses of substance P or its related entities which function in a synergistic relationship and mechanism of action. The methodology relies upon a powerful potentiation and enhancement of an opioid-mediated response by the enhancing action of substance P to modulate or eliminate pain and other nociceptive responses, as well as inducing anesthesia.

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