James R Potter, Age 61Riviera Beach, MD

8071304, Dec 6, 2011

Apr 5, 2004

10/818037

Steven R. Brant - Reisterstown MD, US
Amir Karban - Baltimore MD, US
Franklin Nouvet - Laurel MD, US
Theodore M. Bayless - Baltimore MD, US
James J. Potter - Baltimore MD, US
Esteban Mezey - Baltimore MD, US
Toshihiko Okazaki - Baltimore MD, US

The Johns Hopkins University - Baltimore MD

C12Q 1/68
C12P 19/34
C07H 21/02
C07H 21/04

435 611, 435 61, 435 612, 435 617, 435 912, 536 241, 536 2431, 536 2433

The present invention discloses a functional relationship between a recognized disease condition and a polymorphism in the nucleotide factor kappa B promoter (NFKB1). This relationship provides a platform for methods of altering promoter activity and for determining similar relationships between specific pathologies and identified polymorphisms. A statistically significant risk of developing ulcerative colitis was shown to be correlated with the presence of an ATTG insertion/deletion in the NFKB1 promoter and is likely to apply also to a variety of other inflammatory diseases.

2012012, May 17, 2012

Nov 7, 2011

13/290678

Steven R. Brant - Reisterstown MD, US
Amir Karban - Baltimore MD, US
Franklin Nouvet - Severn MD, US
Theodore M. Bayless - Baltimore MD, US
James J. Potter - Baltimore MD, US
Esteban Mezey - Baltimore MD, US
Toshihiko Okazaki - Baltimore MD, US

THE JOHNS HOPKINS UNIVERSITY - Baltimore MD

A61K 38/17
A61P 29/00
C07K 14/435
C07H 21/04
C12Q 1/68
G01N 33/566

514 11, 435 611, 436501, 530350, 536 241, 536 243

The present invention discloses a functional relationship between a recognized disease condition and a polymorphism in the nucleotide factor kappa B promoter (NFKB1). This relationship provides a platform for methods of altering promoter activity and for determining similar relationships between specific pathologies and identified polymorphisms. A statistically significant risk of developing ulcerative colitis was shown to be correlated with the presence of an ATTG insertion/deletion in the NFKB1 promoter and is likely to apply also to a variety of other inflammatory diseases.

6201355, Mar 13, 2001

Nov 8, 1999

9/436275

Gary L. Morgan - Elkridge MD
James M. Potter - Los Alamos NM

Triton Thalassic Technologies, Inc. - Ridgefield CT

H05B 4116

315248

The apparatus is a gas filled ultraviolet generating lamp for use as a liquid purifier. The lamp is powred by high voltage AC, but has no metallic electrodes within or in contact with the gas enclosure which is constructed as two concentric quartz cylinders sealed together at their ends with the gas fill between the cylinders. Cooling liquid is pumped through the volume inside the inner quartz cylinder where an electrically conductive pipe spaced from the inner cylinder is used to supply the cooling liquid and act as the high voltage electrode. The gas enclosure is enclosed within but spaced from a metal housing which is connected to operate as the ground electrode of the circuit and through which the treated fluid flows. Thus, the electrical circuit is from the central pipe, and through the cooling liquid, the gas enclosure, the treated liquid on the outside of the outer quartz cylinder, and to the housing. The high voltage electrode is electrically isolated from the source of cooling liquid by a length of insulated hose which also supplies the cooling liquid.

5834784, Nov 10, 1998

May 2, 1997

8/850143

Gary L. Morgan - Elkridge MD
James M. Potter - Los Alamos NM

Triton Thalassic Technologies, Inc. - Ridgefield CT

G01N 2100

250436

The apparatus is a gas filled ultraviolet generating lamp for use as a liquid purifier. The lamp is powered by high voltage AC, but has no metallic electrodes within or in contact with the gas enclosure which is constructed as two concentric quartz cylinders sealed together at their ends with the gas fill between the cylinders. Cooling liquid is pumped through the volume inside the inner quartz cylinder where an electrically conductive pipe spaced from the inner cylinder is used to supply the cooling liquid and act as the high voltage electrode. The gas enclosure is enclosed within but spaced from a metal housing which is connected to operate as the ground electrode of the circuit and through which the treated fluid flows. Thus, the electrical circuit is from the central pipe, and through the cooling liquid, the gas enclosure, the treated liquid on the outside of the outer quartz cylinder, and to the housing. The high voltage electrode is electrically isolated from the source of cooling liquid by a length of insulated hose which also supplies the cooling liquid.

2014024, Sep 4, 2014

Oct 4, 2013

14/046114

- Baltimore MD, US
Amir Karban - Baltimore MD, US
Franklin Nouvet - Severn MD, US
Theodore M. Bayless - Baltimore MD, US
James J. Potter - Baltimore MD, US
Esteban Mezey - Baltimore MD, US
Toshihiko Okazaki - Baltimore MD, US

THE JOHNS HOPKINS UNIVERSITY - Baltimore MD

C12Q 1/68
C12N 15/113

536 235, 536 2431, 536 241

The present invention discloses a functional relationship between a recognized disease condition and a polymorphism in the nucleotide factor kappa B promoter (NFKB1). This relationship provides a platform for methods of altering promoter activity and for determining similar relationships between specific pathologies and identified polymorphisms. A statistically significant risk of developing ulcerative colitis was shown to be correlated with the presence of an ATTG insertion/deletion in the NFKB1 promoter and is likely to apply also to a variety of other inflammatory diseases.