Inventors:
Hassan Sahouani - Hastings MN, US
Robert A. Scherrer - White Bear Lake MN, US
Kim M. Vogel - Lake Elmo MN, US
Dennis E. Vogel - Lake Elmo MN, US
Stephen W. Stein - Lino Lakes MN, US
Brian J. Gabrio - Hugo MN, US
Stephanie F. Bernatchez - Woodbury MN, US
Richard H. Ferber - Fridley MN, US
Wei Zou - Woodbury MN, US
International Classification:
A61K 9/16
A61K 47/12
Abstract:
The invention comprises compositions and methods useful for encapsulation and controlled release of guest molecules, such as drugs. Compositions of the present invention comprise a matrix comprising molecules that are non-covalently crosslinked by multi-valent cations, wherein the molecules that are non-covalently crosslinked are non-polymeric, have more than one carboxy functional group, and have at least partial aromatic or heteroaromatic character The compositions are characterized in that a guest molecule may be encapsulated within the matrix and subsequently released.