Roger H Pak, Age 58765 Liberty Square Rd, Acton, MA 01719

Roger Pak Phones & Addresses

765 Liberty Square Rd, Boxborough, MA 01719 (978) 266-9779

Boxboro, MA

59 Russet Ln, Southington, CT 06489 (860) 620-1115

Middletown, CT

Sherman Oaks, CA

Davis, CA

Los Angeles, CA

Waltham, MA

59 Russet Ln, Southington, CT 06489

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Roger H Pak

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Position: Sales Occupations

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Degree: Graduate or professional degree

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Roger Pak

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Us Patents

Analogs Of Benzoquinone-Containing Ansamycins And Methods Of Use Thereof

US Patent:
7282493, Oct 16, 2007
Filed:
Dec 23, 2004
Appl. No.:
11/022057
Inventors:
Julian Adams - Boston MA, US
Yun Gao - Southborough MA, US
Asimina T. Georges Evangelinos - Chestnut Hill MA, US
Louis Grenier - Brookline MA, US
Roger H. Pak - Boxborough MA, US
James R. Porter - Brighton MA, US
James L. Wright - Lexington MA, US
Assignee:
Infinity Pharmaceuticals, Inc. - Cambridge MA
International Classification:
C07D 225/06
C07D 211/60
C07D 498/08
A61K 31/395
A61K 35/00
US Classification:
514183, 5142298, 514375, 540456, 540461, 540462
Abstract:
The present invention provides analogs of benzoquinone-containing ansamycins and uses thereof for treating and modulating disorders associated with hyperproliferation, such as cancer. The present invention provides analogs of benzoquinone-containing ansamycins where the benzoquinone is reduced to a hydroquinone and trapped by reaction with a suitable acid, preferably ones that increase the solubility and air stability of the resulting 17-ammonium hydroquinone ansamycin analog.

Analogs Of Benzoquinone-Containing Ansamycins And Methods Of Use Thereof

US Patent:
7375217, May 20, 2008
Filed:
Apr 14, 2005
Appl. No.:
11/108165
Inventors:
Julian Adams - Boston MA, US
Yun Gao - Southborough MA, US
Asimina T. Georges Evangelinos - Chestnut Hill MA, US
Louis Grenier - Brookline MA, US
Roger H. Pak - Boxborough MA, US
James R. Porter - Brighton MA, US
James L. Wright - Lexington MA, US
Assignee:
Infinity Pharmaceuticals, Inc. - Cambridge MA
International Classification:
C07D 225/06
US Classification:
540456, 540461, 540462
Abstract:
The present invention provides analogs of benzoquinone-containing ansamycins and uses thereof for treating and modulating disorders associated with hyperproliferation, such as cancer. The present invention provides analogs of benzoquinone-containing ansamycins where the benzoquinone is reduced to a hydroquinone and trapped by reaction with a suitable acid, preferably ones that increase the solubility and air stability of the resulting 17-ammonium hydroquinone ansamycin analog.

Analogs Of Benzoquinone-Containing Ansamycins And Methods Of Use Thereof

US Patent:
7566706, Jul 28, 2009
Filed:
Apr 13, 2005
Appl. No.:
11/105203
Inventors:
Julian Adams - Boston MA, US
Yun Gao - Southborough MA, US
Asimina T. Georges Evangelinos - Chestnut Hill MA, US
Louis Grenier - Brookline MA, US
Roger H. Pak - Boxborough MA, US
James R. Porter - Brighton MA, US
James L. Wright - Lexington MA, US
Assignee:
Infinity Pharmaceuticals, Inc. - Cambridge MA
International Classification:
A61P 35/00
US Classification:
514183, 5142298, 514375
Abstract:
The present invention provides analogs of benzoquinone-containing ansamycins and uses thereof for treating and modulating disorders associated with hyperproliferation, such as cancer. The present invention provides analogs of benzoquinone-containing ansamycins where the benzoquinone is reduced to a hydroquinone and trapped by reaction with a suitable acid, preferably ones that increase the solubility and air stability of the resulting 17-ammonium hydroquinone ansamycin analog.

Analogs Of Benzoquinone-Containing Ansamycins And Methods Of Use Thereof

US Patent:
7579337, Aug 25, 2009
Filed:
Aug 27, 2008
Appl. No.:
12/199415
Inventors:
Julian Adams - Boston MA, US
Yun Gao - Southborough MA, US
Asimina T. Georges Evangelinos - Chestnut Hill MA, US
Louis Grenier - Newton MA, US
Roger H. Pak - Boxborough MA, US
James R. Porter - Rowley MA, US
James L. Wright - Lexington MA, US
Assignee:
Infinity Pharmaceuticals, Inc. - Cambridge MA
International Classification:
C07D 225/06
A61K 31/395
A61P 35/00
US Classification:
514183, 540456
Abstract:
The present invention provides analogs of benzoquinone-containing ansamycins and uses thereof for treating and modulating disorders associated with hyperproliferation, such as cancer. The present invention provides analogs of benzoquinone-containing ansamycins where the benzoquinone is reduced to a hydroquinone and trapped by reaction with a suitable acid, preferably ones that increase the solubility and air stability of the resulting 17-ammonium hydroquinone ansamycin analog.

Analogs Of Benzoquinone-Containing Ansamycins And Methods Of Use Thereof

US Patent:
7608613, Oct 27, 2009
Filed:
Aug 27, 2008
Appl. No.:
12/199211
Inventors:
Julian Adams - Boston MA, US
Yun Gao - Southborough MA, US
Asimina T. Georges Evangelinos - Chestnut Hill MA, US
Louis Grenier - Newton MA, US
Roger H. Pak - Boxborough MA, US
James R. Porter - Rowley MA, US
James L. Wright - Lexington MA, US
Assignee:
Infinity Pharmaceuticals, Inc. - Cambridge MA
International Classification:
C07D 225/04
A61K 31/395
A61K 31/7016
US Classification:
514183, 5142298, 514375, 540456, 540461, 540462
Abstract:
The present invention provides analogs of benzoquinone-containing ansamycins and uses thereof for treating and modulating disorders associated with hyperproliferation, such as cancer. The present invention provides analogs of benzoquinone-containing ansamycins where the benzoquinone is reduced to a hydroquinone and trapped by reaction with a suitable acid, preferably ones that increase the solubility and air stability of the resulting 17-ammonium hydroquinone ansamycin analog.

Analogs Of Benzoquinone-Containing Ansamycins And Methods Of Use Thereof

US Patent:
7691840, Apr 6, 2010
Filed:
Feb 11, 2009
Appl. No.:
12/369549
Inventors:
Julian Adams - Boston MA, US
Yun Gao - Southborough MA, US
Asimina T. Georges Evangelinos - Chestnut Hill MA, US
Louis Grenier - Newton MA, US
Roger H. Pak - Boxborough MA, US
James R. Porter - Rowley MA, US
James L. Wright - Lexington MA, US
Assignee:
Infinity Pharmaceuticals, Inc. - Cambridge MA
International Classification:
A61P 35/00
US Classification:
514183
Abstract:
The present invention provides analogs of benzoquinone-containing ansamycins and uses thereof for treating and modulating disorders associated with hyperproliferation, such as cancer. The present invention provides analogs of benzoquinone-containing ansamycins where the benzoquinone is reduced to a hydroquinone and trapped by reaction with a suitable acid, preferably ones that increase the solubility and air stability of the resulting 17-ammonium hydroquinone ansamycin analog.

Analogs Of Benzoquinone-Containing Ansamycins And Methods Of Use Thereof

US Patent:
7767662, Aug 3, 2010
Filed:
Aug 27, 2008
Appl. No.:
12/199356
Inventors:
Julian Adams - Boston MA, US
Yun Gao - Southborough MA, US
Asimina T. Georges Evangelinos - Chestnut Hill MA, US
Louis Grenier - Newton MA, US
Roger H. Pak - Boxborough MA, US
James R. Porter - Rowley MA, US
James L. Wright - Lexington MA, US
Assignee:
Infinity Pharmaceuticals, Inc. - Cambridge MA
International Classification:
A61K 31/395
A61K 35/00
C07D 225/06
C07D 211/60
C07D 498/08
US Classification:
514183, 540456
Abstract:
The present invention provides analogs of benzoquinone-containing ansamycins and uses thereof for treating and modulating disorders associated with hyperproliferation, such as cancer. The present invention provides analogs of benzoquinone-containing ansamycins where the benzoquinone is reduced to a hydroquinone and trapped by reaction with a suitable acid, preferably ones that increase the solubility and air stability of the resulting 17-ammonium hydroquinone ansamycin analog.

Analogs Of Benzoquinone-Containing Ansamycins And Methods Of Use Thereof

US Patent:
7767663, Aug 3, 2010
Filed:
Feb 11, 2009
Appl. No.:
12/369545
Inventors:
Julian Adams - Boston MA, US
Yun Gao - Southborough MA, US
Asimina T. Georges Evangelinos - Chestnut Hill MA, US
Louis Grenier - Newton MA, US
Roger H. Pak - Boxborough MA, US
James R. Porter - Rowley MA, US
James L. Wright - Lexington MA, US
Assignee:
Infinity Pharmaceuticals, Inc. - Cambridge MA
International Classification:
A61P 35/00
US Classification:
514183
Abstract:
The present invention provides analogs of benzoquinone-containing ansamycins and uses thereof for treating and modulating disorders associated with hyperproliferation, such as cancer. The present invention provides analogs of benzoquinone-containing ansamycins where the benzoquinone is reduced to a hydroquinone and trapped by reaction with a suitable acid, preferably ones that increase the solubility and air stability of the resulting 17-ammonium hydroquinone ansamycin analog.

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