Ronald T Yamamoto, Age 851270 Hawes St, Redwood City, CA 94061

6458140, Oct 1, 2002

Jan 26, 2001

09/771007

Jodi Akin - Alamo CA
Amr Salahieh - Campbell CA
Michael Mack - Dallas TX
Hani Shennib - Quebec, CA
Jackson Demond - Santa Cruz CA
Ronald K. Yamamoto - San Francisco CA
Stanley R. Conston - San Carlos CA

Vasconnect, Inc. - Walnut Creek CA

A61B 1704

606153, 606154, 606155

The present invention provides implantable devices and associated methods forinterconnecting human vessels in a side-to-side or an end-to-side arrangement rapidly, safely and in a minimally invasive manner. The devices comprises at least a first segment, a second component, and a flow opening between the at least one segment and the second component when operatively used. The first segment is flexible and has physical and mechanical properties which allow it to be easily inserted into a vessel, to conformably seal with the inside wall of the vessel and to be resistant to dislodging from the vessel. The second component may comprise a second segment having the same or a similar configuration as the first segment or may be a tubular member which extends from the first segment. The first and second segments are flexible for easy insertion into an incision made within the side of each vessel. Upon release from a constricted state, each flexible segment subsequently conforms to the interior walls of a vessel to provide a sealing contact along the contact surface of the segment inserted within.

6524608, Feb 25, 2003

Mar 27, 2001

09/819117

Thomas B. Ottoboni - Belmont CA
Ronald K. Yamamoto - San Francisco CA
Stanley R. Conston - San Carlos CA

Point Biomedical Corporation - San Carlos CA

A61F 202

424426, 424430, 5147723

Bioerodible, sustained release preparations are provided for placement into the bladder through the urethra which provided sustained release of drugs. Configurations are provided which are insertable through a catheter, such as a coiled filament, patch or a flowable gel. The device is bioeroded during or after the sustained release of the drug such that there is no blockage of the urinary tract while the device is in place within the bladder.

6764517, Jul 20, 2004

Feb 22, 2002

10/086225

Ronald K. Yamamoto - San Francisco CA
Michael K. Kwan - Cupertino CA
Stephen D. Pacetti - San Jose CA

DePuy AcroMed, Inc. - Raynham MA

A61F 228

623 2351, 623 2361, 623 2375, 424423, 424424, 424425

A porous three-dimensional tissue repair matrix is provided which is biodegradable. The matrix is preferably formed from mineralized collagen where the mineral comprises particulate calcium phosphate immobilized in the matrix.

6776761, Aug 17, 2004

Aug 20, 2002

10/225252

Thomas B. Ottoboni - Belmont CA
E. Glenn Tickner - Watsonville CA
Robert E. Short - Los Gatos CA
Ronald K. Yamamoto - San Francisco CA

Point Biomedical Corporation - San Carlos CA

A61B 814

600458, 600437, 600454, 424 951, 424 952

A composition for ultrasonic imaging is described having a microbubble population of controlled fragility. The microbubbles comprise an outer shell and a hollow core. The ratio of shell thickness to microbubble diameter is substantially similar across the population of microbubbles. A method of using such composition for imaging a fluid filled cavity, vessel or tissue is described.

6896659, May 24, 2005

Oct 22, 2001

10/028738

Stanley R. Conston - San Carlos CA, US
Ronald Yamamoto - San Francisco CA, US
Thomas B. Ottoboni - Belmont CA, US
E. Glenn Tickner - Watsonville CA, US

Point Biomedical Corporation - San Carlos CA

A61B008/14

600458

A method is provided for site specific delivering therapeutic or diagnostic agents to a region in a fluid-filled cavity, vessel or tissue using an agent-loaded microbubble population. The population has controlled fragility characterized by a uniform wall thickness to diameter ratio which defines the discrete threshold intensity value of ultrasonic power where microbubble rupture occurs in the population. The location of the microbubble population may be monitored by ultrasound to determine its presence at the region prior to application of the ultrasonic power to rupture to microbubbles.

6902584, Jun 7, 2005

Feb 13, 2001

09/782794

Michael K. Kwan - Cupertino CA, US
Stephen D. Pacetti - Sunnyvale CA, US
Ronald K. Yamamoto - San Francisco CA, US

Depuy Spine, Inc. - Raynham MA

A61F002/28

623 2351, 623 2361, 623 2375, 424426

A porous three-dimensional bone grafting matrix is provided which is biodegradable. The matrix is preferably formed from mineralized collagen where the mineral comprises particulate calcium phosphate immobilized in the matrix and having a particle size of 5 microns or less.

7229440, Jun 12, 2007

Feb 20, 2004

10/783714

Huddee Jacob Ho - San Jose CA, US
Roberta Lee - Redwood City CA, US
Samuel E. Zuckswert - San Jose CA, US
Stanley R. Conston - San Carlos CA, US
Ronald Yamamoto - San Francisco CA, US
Don Alden - Sunnyvale CA, US

Manoa Medical, Inc. - Redwood City CA

A61B 18/14

606 47, 606113, 606114

Devices and methods for a minimally invasive procedure for cutting tissue are disclosed. The device generally includes a probe with a distal exit at an exit angle relative to the probe, a cutting loop with shape memory having a preconfigured shape, and a loop securing mechanism to secure the cutting loop in a penetrating configuration and to release the cutting loop into a cutting configuration. The cutting loop is generally within a profile of the probe in the penetrating configuration. In the cutting configuration, the cutting loop extends through the cutting loop exit and generally returns to the preconfigured shape at a cutting angle generally defined by the exit angle. The cutting loop securing mechanism may be, for example, a cover slidable over the probe, a slidable member extending from a distal tip of the probe, or a groove defined in the probe proximal to the cutting loop exit.

7699882, Apr 20, 2010

Sep 17, 2003

10/528276

Robert Stamper - Berkeley CA, US
Stanley R. Conston - San Carlos CA, US
Ronald K. Yamamoto - San Francisco CA, US

iScience Interventional Corporation - Menlo Park CA

A61F 2/06
A61F 9/00

623 111

The invention provides minimally invasive microsurgical tools and methods to form an aqueous humor shunt or bypass for the treatment of glaucoma. The invention enables surgical creation of a tissue tract () within the tissues of the eye to directly connect a source of aqueous humor such as the anterior chamber (), to an ocular vein (). The tissue tract () from the vein () may be connected to any source of aqueous humor, including the anterior chamber (), an aqueous collector channel, Schlemm's canal (), or a drainage bleb. Since the aqueous humor passes directly into the venous system, the normal drainage process for aqueous humor is restored. Furthermore, the invention discloses devices and materials that can be implanted in the tissue tract to maintain the tissue space and fluid flow.