Roy A Swaringen, Age 82824 Sandlewood Dr, Durham, NC 27712

Roy Swaringen Phones & Addresses

824 Sandlewood Dr, Durham, NC 27712 (919) 477-0371 (919) 477-2227

882 Sandlewood Dr, Durham, NC 27712 (919) 477-2227

824 Sandlewood Dr, Durham, NC 27712 (919) 477-0371

Social networks

Roy A Swaringen

Linkedin

Work

Company: Roy a. swaringen consulting Jul 1995 Position: Owner

Education

Degree: PhD School / High School: University of Illinois at Urbana-Champaign 1964 to 1969 Specialities: Organic Chemistry

Skills

Gmp • Fda • Pharmaceutical Industry • Validation • Chemistry • Technology Transfer • Regulatory Submissions • R&D • Sop • Biotechnology • Process Simulation • Clinical Trials • Laboratory • Drug Development • Life Sciences • Quality Assurance • Cro • Regulatory Affairs • Clinical Development • Patents • V&V • Optimization • Manufacturing • Lifesciences • Pharmaceutics • Quality Control • Process Validation • Due Diligence • Ind • Oncology • U.s. Food and Drug Administration • Standard Operating Procedure • Process Development • Process Chemistry • Cgmp

Industries

Pharmaceuticals

Mentions for Roy A Swaringen

Roy Swaringen resumes & CV records

Resumes

Roy Swaringen Photo 9

Owner

Location:
824 Sandlewood Dr, Durham, NC 27712
Industry:
Pharmaceuticals
Work:
Roy A. Swaringen Consulting since Jul 1995
Owner
Institution since Jan 1995
s
Burroughs Wellcome Co Sep 1970 - Jul 1995
Director of Chemical Development
Education:
University of Illinois at Urbana-Champaign 1964 - 1969
PhD, Organic Chemistry
University of Illinois 1966
M.S, Organic Chemistry
Skills:
Gmp, Fda, Pharmaceutical Industry, Validation, Chemistry, Technology Transfer, Regulatory Submissions, R&D, Sop, Biotechnology, Process Simulation, Clinical Trials, Laboratory, Drug Development, Life Sciences, Quality Assurance, Cro, Regulatory Affairs, Clinical Development, Patents, V&V, Optimization, Manufacturing, Lifesciences, Pharmaceutics, Quality Control, Process Validation, Due Diligence, Ind, Oncology, U.s. Food and Drug Administration, Standard Operating Procedure, Process Development, Process Chemistry, Cgmp

Publications & IP owners

Us Patents

Preparation Of Pharmaceutical Salts Of 3-O-(3',3'-Dimethylsuccinyl)Betulinic Acid

US Patent:
2007020, Aug 30, 2007
Filed:
Dec 18, 2006
Appl. No.:
11/640488
Inventors:
Christian Hemp - Bacharach, DE
Arndt Hausherr - Mainz, DE
Theodore Nitz - Boyds MD, US
Roy Swaringen - Durham NC, US
International Classification:
A61K 31/56
C07J 53/00
US Classification:
514169000, 552511000
Abstract:
This invention relates to a novel process for making 3-O-(3′,3′-dimethylsuccinyl)betulinic acid (“DSB”). This invention also relates to methods of treating HIV and related diseases using pharmaceutical compositions comprising salt forms of DSB prepared according to the process of the present invention. The invention further relates to dosage forms of pharmaceutical compositions comprising salts of DSB made using the process of this invention.

Preparation Of Bile Acids And Intermediates Thereof

US Patent:
2010017, Jul 15, 2010
Filed:
May 16, 2008
Appl. No.:
12/153446
Inventors:
Achampeta Prasad - Hyderabad, IN
Roy Swaringen - Durham NC, US
John Reid - Niskayuma NY, US
Robert Moriarty - Michiana Shores IN, US
Akhila Sahoo - Bhubaneswar, Orissa, IN
Assignee:
Kythera Biopharmaceuticals, Inc. - CALABASAS CA
International Classification:
C07J 75/00
C07J 1/00
C07J 7/00
US Classification:
552553000, 552623000, 552599000
Abstract:
Synthetic methods for preparing deoxycholic acid and intermediates thereof are provided.

Preparation Of Pharmaceutical Salts Of 3-0-(3',3'-Dimethylsuccinyl) Betulinic Acid

US Patent:
2011031, Dec 22, 2011
Filed:
Jul 5, 2011
Appl. No.:
13/176592
Inventors:
Christian Hemp - Bacharach, DE
Arndt Hausherr - Mainz, DE
Theodore John Nitz - Boyds MD, US
Roy Swaringen - Durham NC, US
Assignee:
Myrexis, Inc. - Salt Lake City UT
International Classification:
C07C 69/73
US Classification:
560176
Abstract:
This invention relates to a novel process for making 3-O-(3′,3′-dimethylsuccinyl)betulinic acid (“DSB”). This invention also relates to methods of treating HIV and related diseases using pharmaceutical compositions comprising salt forms of DSB prepared according to the process of the present invention. The invention further relates to dosage forms of pharmaceutical compositions comprising salts of DSB made using the process of this invention.

Method Of Preparing Isomers Of Bis Isoquinolinium Compounds

US Patent:
4491665, Jan 1, 1985
Filed:
Apr 13, 1981
Appl. No.:
6/253299
Inventors:
Hassan A. El-Sayad - Chapel Hill NC
Roy A. Swaringen - Durham NC
David A. Yeowell - Chapel Hill NC
Assignee:
Burroughs Wellcome Co. - Research Triangle Park NC
International Classification:
C07D40110
A61K 3147
US Classification:
546140
Abstract:
This invention provides the neuromuscular blocking agents of formula (I): ##STR1## where B and C are each a group of formula (II) and are meta or para to one another: ##STR2## wherein D is CH. sub. 2 CH. sub. 2 or CH. dbd. CH (preferably trans); Y is alkyl of 1-4 carbon atoms (methyl, ethyl, propyl or butyl); E and F and H or OCH. sub. 3 ; X. sup. - is an anion, preferably pharmaceutically acceptable; and the substituted benzyl and substituted propyl groups are in a trans relationship relative to each other in the nitrogen-containing ring. Methods for preparing the compounds, pharmaceutical formulations containing the compounds, and their use are also described.

Synthesis Of 2,4-Diamino-5-Benzylpyrimidines Using Benzyl Cyanoacetal Intermediates

US Patent:
4216319, Aug 5, 1980
Filed:
Nov 24, 1978
Appl. No.:
5/963399
Inventors:
David A. Yeowell - Chapel Hill NC
Roy A. Swaringen - Durham NC
Assignee:
Burroughs Wellcome Co. - Research Triangle Park NC
International Classification:
C07D23948
US Classification:
544325
Abstract:
Benzyl cyanoacetals of formula: ##STR1## wherein R. sup. 1, R. sup. 2 and R. sup. 3 are the same or different and each is a halogen or a hydrogen atom, an alkoxy group, an alkyl group, or a dialkylamino group; R. sup. 4 is an alkoxycarbonyl group, or an aldehyde group; and R. sup. 5 is an alkyl group; the alkyl or alkoxy groups each having from 1 to 4 carbon atoms, and their use as intermediates in the preparation of antibacterial 2,4-diamino-5-benzylpyrimidines. They are prepared from a reaction between an orthoester and an. alpha. -substituted-. beta. -benzylpropionitrile and then the resulting cyanoacetal is converted to the benzylpyrimidine by reaction with guanidine.

Synthesis Of Leucovorin

US Patent:
4500711, Feb 19, 1985
Filed:
Dec 22, 1980
Appl. No.:
6/218554
Inventors:
James C. Wisowaty - Chapel Hill NC
Roy A. Swaringen - Durham NC
David A. Yeowell - Chapel Hill NC
Assignee:
Burroughs Wellcome Co. - Research Triangle Park NC
International Classification:
C07D47504
US Classification:
544258
Abstract:
In the synthesis of calcium leucovorin (calcium 5-formyl-5,6,7,8-tetrahydrofolate), the use of an amine base in the conversion of anhydroleucovorin (5,10-methenyl-5,6,7,8-tetrahydrofolic acid) to leucovorin unexpectedly results in a pure (USP) product directly from the reaction mixture.

Novel Compounds

US Patent:
4761418, Aug 2, 1988
Filed:
Jul 17, 1985
Appl. No.:
6/756025
Inventors:
Roy A. Swaringen - Durham NC
Hassan A. El-Sayad - Nasr City, EG
David A. Yeowell - Chapel Hill NC
John J. Savarese - Boxford MA
Assignee:
Burroughs Wellcome Co. - Research Triangle Park NC
General Hospital Corporation - Boston MA
International Classification:
A61K 3147
C07C40114
US Classification:
514308
Abstract:
Neuromuscular blocking agents of formula (1) which are useful as skeletal muscle relaxants during surgery are disclosed. ##STR1## and X is an anion, preferably pharmaceutically acceptable.

Long Duration Neuromuscular Blocking Agents

US Patent:
4701460, Oct 20, 1987
Filed:
Jan 25, 1985
Appl. No.:
6/694908
Inventors:
Hassan A. El-Sayad - Chapel Hill NC
Roy A. Swaringen - Durham NC
David A. Yeowell - Chapel Hill NC
Assignee:
Burroughs Wellcome Co. - Research Triangle Park NC
International Classification:
A61K 3147
C07D40112
US Classification:
514308
Abstract:
Long duration muscle relaxant compound of formula (I) ##STR1## and its use in producing muscle relaxation in mammals including man.

Public records

Vehicle Records

Roy Swaringen

Address:
824 Sandlewood Dr, Durham, NC 27712
Phone:
(919) 477-0371
VIN:
1G1YY26E475108251
Make:
CHEVROLET
Model:
CORVETTE
Year:
2007

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