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Ruth A Gjerset, Age 757812 Camino Noguera, San Diego, CA 92122

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Known as:
Ruth Gjerset Agreement Ruth A G Parello
Related to:
Keith Arthur Boyd Herbert Hastings

Ruth Gjerset Phones & Addresses

7812 Camino Noguera, San Diego, CA 92122 (858) 452-0328

4322 Hill St, San Diego, CA 92107 (619) 222-7564

9675 Easter Way, San Diego, CA 92121

La Jolla, CA

Social networks

Ruth A Gjerset

Linkedin

Work

Company: Torrey pines institute for molecular studies Mar 2009 to Jun 2014 Position: Member and head of cancer cell biology

Education

School / High School: Uc San Diego 1986 to 1990

Languages

French • English

Industries

Biotechnology

Mentions for Ruth A Gjerset

Ruth Gjerset resumes & CV records

Resumes

Ruth Gjerset Photo 1

Chief Executive Officer

Location:
3550 General Atomics Ct, San Diego, CA 92121
Industry:
Biotechnology
Work:
Torrey Pines Institute For Molecular Studies Mar 2009 - Jun 2014
Member and Head of Cancer Cell Biology Rg Biopharma Mar 2009 - Jun 2014
Chief Executive Officer Sidney Kimmel Cancer Center Aug 1991 - Mar 2009
Associate Professor
Education:
Uc San Diego 1986 - 1990
University of California, San Francisco
Doctorates, Doctor of Philosophy, Biochemistry, Biophysics, Philosophy Uc San Diego
Bachelors, Bachelor of Arts, Biology
Languages:
French
English

Publications & IP owners

Us Patents

Methods And Compositions For Topoisomerase I Modulated Tumor Suppression

US Patent:
8431353, Apr 30, 2013
Filed:
Oct 6, 2010
Appl. No.:
12/898872
Inventors:
Ruth A. Gjerset - San Diego CA, US
Keya Bandyopadhyay - San Diego CA, US
Assignee:
RG Biopharma LLC - San Diego CA
International Classification:
G01N 33/574
C12Q 1/00
A01N 43/42
US Classification:
435 723, 435 4, 514283
Abstract:
Disclosed herein are methods and compositions for determining the sensitivity or enhancing the sensitivity of cells to the effects of topoisomerase I inhibitors. Also disclosed are methods and compositions for inducing cell death, apoptosis and/or growth arrest which may be used for tumor suppression.

Enhancing The Sensitivity Of Tumor Cells To Therapies

US Patent:
2002000, Jan 17, 2002
Filed:
Jan 26, 2001
Appl. No.:
09/769752
Inventors:
Robert Sobol - Rancho Santa Fe CA, US
Ruth Gjerset - San Diego CA, US
International Classification:
A61K048/00
US Classification:
514/044000
Abstract:
A method for enhancing the effect of a cancer therapy by introducing wild-type therapy-sensitizing gene activity into tumor cells having mutant therapy-sensitizing gene activity and subjecting the tumor cells to a cancer therapy such as chemotherapy, radiotherapy, biological therapy including immunotherapy, cryotherapy and hyperthermia.

Enhancing The Sensitivity Of Tumor Cells To Therapies

US Patent:
2002001, Jan 24, 2002
Filed:
Jan 10, 2001
Appl. No.:
09/758956
Inventors:
Robert Sobol - Rancho Santa Fe CA, US
Ruth Gjerset - San Diego CA, US
International Classification:
A61K048/00
US Classification:
514/044000
Abstract:
A method for enhancing the effect of a cancer therapy by introducing wild-type therapy-sensitizing gene activity into tumor cells having mutant therapy-sensitizing gene activity and subjecting the tumor cells to a cancer therapy such as chemotherapy, radiotherapy, biological therapy including immunotherapy, cryotherapy and hyperthermia.

Enhancing The Sensitivity Of Tumor Cells To Therapies

US Patent:
2004007, Apr 15, 2004
Filed:
Feb 25, 2003
Appl. No.:
10/374665
Inventors:
Robert Sobol - Rancho Santa Fe CA, US
Ruth Gjerset - San Diego CA, US
International Classification:
A61K048/00
US Classification:
514/044000
Abstract:
A method for enhancing the effect of a cancer therapy by introducing wild-type therapy-sensitizing gene activity into tumor cells having mutant therapy-sensitizing gene activity and subjecting the tumor cells to a cancer therapy such as chemotherapy, radiotherapy, biological therapy including immunotherapy, cryotherapy and hyperthermia.

Tumor Suppression Through Bicistronic Co-Expression Of P53 And P14Arf

US Patent:
2005003, Feb 10, 2005
Filed:
Nov 19, 2003
Appl. No.:
10/717845
Inventors:
Ruth Gjerset - San Diego CA, US
Yinghui Huang - San Diego CA, US
Neshat Saadatmandi - San Diego CA, US
International Classification:
A61K048/00
A61K009/127
C12N015/86
US Classification:
514044000, 424450000, 435320100, 435456000
Abstract:
A bicistronic construct of pand pARF, vectors and other delivery vehicles which include the bicistronic construct, and methods of treating cancer using the vectors and bicistronic construct.

Down-Regulation Of Dna Repair To Enhance Sensitivity To P53-Mediated Suppression

US Patent:
2005009, May 5, 2005
Filed:
May 10, 2004
Appl. No.:
10/842718
Inventors:
Ruth Gjerset - San Diego CA, US
International Classification:
A61K048/00
A61K038/17
C12N015/861
US Classification:
424093200, 435456000, 514012000
Abstract:
The present invention details methods for the treatment of cancer. In particular, it concerns the induction of apoptosis in cancer cells following treatment with inhibitors of DNA repair in combination with p53 gene therapy. Treatment of glioblastoma and breast tumor cells with inhibitors of DNA repair induced growth suppression that was a result of p53-mediated apoptosis. Thus it appears that inhibitors of DNA repair in combination with p53 gene therapy is involved in restoration of p53-mediated apoptosis.

Methods And Compositions For Topoisomerase I Modulated Tumor Suppression

US Patent:
2011002, Feb 3, 2011
Filed:
Aug 16, 2007
Appl. No.:
12/377498
Inventors:
Ruth A. Gjerset - San Diego CA, US
Keya Bandyopadhyay - San Diego CA, US
International Classification:
A61K 31/7088
C12N 5/071
A61K 31/4375
C12Q 1/68
C12N 5/09
A61P 35/00
US Classification:
514 44 R, 435325, 514283, 435 6
Abstract:
Disclosed herein are methods and compositions for enhancing the sensitivity of cells to the effects of topoisomerase I inhibitors. Also disclosed are methods and compositions for inducing apoptosis and/or growth arrest which may be used for tumor suppression.

Down-Regulation Of Dna Repair To Enhance Sensitivity To P53-Mediated Apoptosis

US Patent:
6054467, Apr 25, 2000
Filed:
Jul 5, 1996
Appl. No.:
8/675887
Inventors:
Ruth A. Gjerset - San Diego CA
Assignee:
Sidney Kimmel Cancer Center - San Diego CA
International Classification:
A01N 4342
A01N 3718
A61K 3147
A61K 31165
US Classification:
514309
Abstract:
The present invention details methods for the treatment of cancer. In particular it concerns the induction of apoptosis in cancer cells following treatment with inhibitors of DNA repair in combination with p53. Treatment of glioblastoma and breast tumor cells with inhibitors of DNA repair induced growth suppression that was a result of p53-mediated apoptosis. Thus it appears that inhibitors of DNA repair in combination with p53 is involved in restoration of p53-mediated apoptosis.

Possible Relatives

Ruth K Johnson  Ruth R Johnston  Ruth E Stanford  Ruth L Stang  Ruth C Stanley  Ruth G Stanton  Ruth E Stapleton  Ruth Stapp  Ruth H Whitehead  Ruth P Starke 

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