Inventors:
- Wooster OH, US
Stacey L. DEAN - Broadview Heights OH, US
International Classification:
C08G 77/52
C08G 77/18
B01J 13/00
A61K 8/02
A61K 8/11
A61Q 13/00
A61Q 19/00
Abstract:
Disclosed is encapsulated active material product comprising: an active material encapsulated in a sol-gel derived material, the sol-gel derived material including a plurality of alkylsiloxy substituents and the sol-gel derived material obtained from:(a) at least one first alkoxysilane precursor having the formula:where n and m are individually an integer from 1 to 8, Ar is a single-, fused-, or poly-aromatic ring, and each R′ is independently a Cto Calkyl group and(b) optionally, at least one second precursor having the formula:where x is 1, 2, 3 or 4; y is 0, 1, 2, 3; z is 0, 1; the total of x+y+z is 4; each R is independently an organic functional group; each an R′ is independently a Cto Calkyl group and R″ is an organic bridging group, where the sol-gel derived material is the volume of acetone per mass of the dry sol-gel derived composition, when placed in excess acetone and the sol-gel derived material swellable to at least five times its dry mass, when placed in excess acetone, and where the amount of active material encapsulated by the porous sol-gel composition is from about 150 to about 1100% w/w.
